Dr. David Alan Frank MD
Oncologist | Medical Oncology
44 Binney St Medical Oncology, Ma Boston MA, 02115About
Dr. David Frank is an oncologist practicing in Boston, MA. Dr. Frank specializes in the care and treatment of patients with cancer. As an oncologist, Dr. Frank manages and oversees the treatment of a cancer patient after he or she has been diagnosed with the disease. Oncologists will care for their patients throughout the course of the disease. Types of oncologists include medical oncologists, surgical oncologists, radiation oncologists, gynecologic oncologists, pediatric oncologists and hematologist oncologists.
Education and Training
Yale Univ Sch of Med, New Haven Ct 1986
Yale School of Medicine 1984
Board Certification
Internal MedicineAmerican Board of Internal MedicineABIM- Medical Oncology
Provider Details
Expert Publications
Data provided by the National Library of Medicine- StAT signaling in cancer: insights into pathogenesis and treatment strategies.
- Interleukin-13 induction of 15-lipoxygenase gene expression requires p38 mitogen-activated protein kinase-mediated serine 727 phosphorylation of Stat1 and Stat3.
- In vivo activation of signal transducer and activator of transcription 1 after CD154 gene therapy for chronic lymphocytic leukemia is associated with clinical and immunologic response.
- STAT1 mediates differentiation of chronic lymphocytic leukemia cells in response to Bryostatin 1.
- Oral fludarabine has significant activity in patients with previously untreated chronic lymphocytic leukemia, and leads to increased STAT1 levels in vivo.
- IL-6-induced survival of colorectal carcinoma cells is inhibited by butyrate through down-regulation of the IL-6 receptor.
- Isolation of unique STAT5 targets by chromatin immunoprecipitation-based gene identification.
- Genome-wide analysis of STAT target genes: elucidating the mechanism of STAT-mediated oncogenesis.
- The natural product honokiol induces caspase-dependent apoptosis in B-cell chronic lymphocytic leukemia (B-CLL) cells.
- Identification of a genetic signature of activated signal transducer and activator of transcription 3 in human tumors.
- A recombinant IL-4-Pseudomonas exotoxin inhibits protein synthesis and overcomes apoptosis resistance in human CLL B cells.
- Signal transducer and activator of transcription 3 is required for the oncogenic effects of non-small-cell lung cancer-associated mutations of the epidermal growth factor receptor.
- Signal transducer and activator of transcription 1 activation in endothelial cells is a negative regulator of angiogenesis.
- Tyrosine phosphorylation is required for functional activation of disulfide-containing constitutively active STAT mutants.
Treatments
- Extra Corporeal Shockwave Therapy
Dr. David Alan Frank MD's Practice location
David Frank, Md
44 Binney St Medical Oncology, Ma -Boston, MA 02115Get Direction
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Nearest Hospitals
BRIGHAM AND WOMEN'S HOSPITALl
75 FRANCIS STREET BOSTON MA 2115BOSTON CHILDREN'S HOSPITALl
300 LONGWOOD AVENUE BOSTON MA 2115EMORY UNIVERSITY HOSPITALl
1364 CLIFTON ROAD, NE ATLANTA GA 30322WELLSTAR ATLANTA MEDICAL CENTERl
303 PARKWAY DRIVE, NE ATLANTA GA 30312CHILDREN'S HEALTHCARE OF ATLANTA AT EGLESTONl
1405 CLIFTON ROAD, NE ATLANTA GA 30322