Dr. Cathy K. Naughton, MD, FACS

Expert Publications

• Pain and morbidity of transrectal ultrasound guided prostate biopsy: a prospective randomized trial of 6 versus 12 cores.
• Retrograde endopyelotomy in association with active distal ureteral dilation: a contraindication for the use of the 7F ureteral "tail" stent.
• A prospective randomized trial comparing 6 versus 12 prostate biopsy cores: impact on cancer detection.
• Impact of transrectal ultrasound guided prostate biopsy on quality of life: a prospective randomized trial comparing 6 versus 12 cores.
• Optimizing laboratory use of human vas deferens specimens for microsurgical practice.
• Development of an inexpensive artificial vagina for semen collection from rabbits.
• The use of URYX for reversible vasectomy in a rabbit model.
• Does varicocele grade predict vein number and size at microsurgical subinguinal repair?
• Mice expressing a dominant-negative Ret mutation phenocopy human Hirschsprung disease and delineate a direct role of Ret in spermatogenesis.
• Increased seminal reactive oxygen species levels in patients with varicoceles correlate with varicocele grade but not with testis size.
• Status of women in urology: based on a report to the Society of University Urologists.
• Tslc1 (nectin-like molecule-2) is essential for spermatozoa motility and male fertility.
• Does the number and size of veins ligated at left-sided microsurgical subinguinal varicocelectomy affect semen analysis outcomes?

Media Releases

Get to know Urologist Dr. Cathy K. Naughton, who serves patients in Missouri.

A well-educated urologist, Dr. Naughton is in practice with Urology Specialists of St. Luke’s, LLC. She is on staff at St. Luke’s Des Peres Hospital in St. Louis & St. Luke’s Hospital in Chesterfield.

Specializing in all the treatment options of male erectile dysfunction, she has received specialized training in minimally invasive penile implant surgery. She also evaluates and treats the female partner to optimize sexual health for the couple. 

Prior to her current endeavours, Dr. Naughton served as an Assistant Professor of Urologic Surgery & as Director of Male Infertility and Microsurgery within the Department of Surgery, Division of Urologic Surgery at the Washington University School of Medicine from 7/1/2001 – 8/31/2006. She then served as Director of the Center for Sexual Health at Metropolitan Urological Specialists, P.C. from 9/1/2006 – 6/30/2020.  She joined Urology Specialist of St. Luke’s on 7/1/2020.  

She has one the largest experiences in Missouri with neuromodulation therapy including Interstim® and Axonics® nerve treatment for overactive bladder. She offers other advanced treatment options for overactive bladder including Botox injections and Percutaneous Tibial Nerve Stimulation (PTNS) in addition to physical therapy and medical management. She also has specialized training with the Urolift System, a minimally invasive procedure for enlarged prostate (BPH).

Dr. Naughton obtained her Bachelor of Science degree in Biological Life Sciences from the Massachusetts Institute of Technology in 1988. She then graduated Magna Cum Laude with her medical degree from the State University of New York at Buffalo in 1993. 

Furthering her training, she performed her internship and residency in general surgery, and completed her residency in urology at the Washington University School of Medicine in 1999. She then completed a research fellowship of The American Foundation for Urologic Disease at Washington University School of Medicine in 2000, and a subsequent clinical fellowship in male infertility and microsurgery at the Glickman Urological Institute at The Cleveland Clinic Foundation in 2001.

Licensed to practice medicine in Missouri and Illinois, Dr. Naughton is board-certified in urology by the American Board of Urology (ABU). The mission of the ABU is to act for the benefit of the public by establishing and maintaining standards of certification for urologists, and working with certified urologists to achieve lifelong learning to ensure the delivery of high quality, safe, and ethical urologic care. 

Dr. Naughton is a member of the American Urological Association, the American Society for Reproductive Medicine, the Society for the Study of Male Reproduction, and the Society of Women in Urology (serving as President; 5/2006).  Dr. Naugton was inducted a Fellow of the American College of Surgeons (FACS) in 2015.  

Throughout her career, she has published extensively in peer-reviewed journals, including Human Reproduction, the Journal of Endourology, the Journal of Andrology, the Journal of Urology, Urology, and Urologia Intemationalis. In 2008 and 2010, she served on the Editorial Board of the Journal of Andrology and the Journal of Endourology.

Among her citations and consultations, Dr. Naughton serves as a Consultant for Astellas Pharmaceuticals: Vesicare, Myrbetriq (2010 – present), Consultant for Seraphim Life Sciences: Medical Advisor/Consultant for Vasogel (2011), Consultant for St. Louis Women’s Surgery Center Incontinence Institute (2013), and as a Best Doctors Expert Consultant reviewing submitted cases and providing recommendations (2014). 

An authority in her field, she has served as an expert witness, has conducted radio interviews and webcasts, has done television interviews, as well as has taught instructional courses (including lecturing to medical students and serving as an advisor / mentor). She has also conducted numerous presentations and lectures (locally, regionally, and nationally), and has served as an author / editor for multiple books, abstracts, and invited articles. 

Urology, also known as genitourinary surgery, is the branch of medicine that focuses on surgical and medical diseases of the male and female urinary-tract system and the male reproductive organs. Urologists specialize in diseases of the urinary tract and the male reproductive system. Patients may be referred to a urologist if their physician suspects they may need treatment for a condition relating to the bladder, prostate, urethra, testicles, penis, ureters, kidneys, and adrenal glands. 

An avid promoter of plant-based whole foods nutrition and lifestyle changes for general health and weight loss/maintenance, Dr. Naughton was voted by her peers as one of “St. Louis’ Best Doctors of America” for 10 consecutive years (2006-2016) as featured in St. Louis Magazine. She was also awarded the Patients’ Choice Award (2014, 2012, 2011, 2010), On-Time Doctor Award (2016, 2015, 2014, 2009), and Compassionate Doctor Recognition (2015, 2012, 2010).

Among her other most notable achievements include National Kidney Foundation Research Fellowship, St. Louis, MO. 1996-97; AUA Summer Research Conference: Molecular Biology of Male Reproduction, invited as junior investigator, Houston, TX, August 8-10, 1997; Finalist in Resident Essay Competition at 77th Annual Meeting of South Central Section of AUA, Cancun Mexico, Podium Presentation 1/1999; St. Louis Urological Society Justin J. Cordonnier Presentation Contest – 2nd Place, 5/99; The Pfizer Scholarship in Urology Award, 1998; Elisabeth Pickett Research Award, Society of Women in Urology, 1999-2000; The American Foundation for Urologic Disease (AFUD) Research Award Scholar, 1999-2000; The Pfizer Scholarship in Urology Award, 1999; Posters-On-Disk Project, selection for Top 130 posters accepted for presentation at 95th AUA Annual Meeting, 5/2000; Society for Male Reproduction and Urology (SMRU) Travel Award to 56th Annual Meeting of the American Society for Reproductive Medicine (ASRM), October, 2000; American College of Surgeons Faculty Research Fellowship, Washington University, St. Louis, MO, 7/2001-7/2003; Society for the Study of Male Reproduction (SSMR) Traveling Fellowship Award to 96th Annual AUA Meeting, June 1-7, 2001; and Association of American Medical Colleges (AAMC) Early Career Women Faculty Professional Development Seminar, Washington DC, July 8-12, 2006. 

On a more personal note, Dr. Naughton’s special interests include running marathons and triathlons, practicing Tae Kwon Do – Began (currently a black belt), swimming (Masters Swimming, Center of Clayton), and doing Bikram Yoga and Sumits Hot Yoga.

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