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Dr. Edward Leslie Cole MD, Pain Management Specialist
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Dr. Edward Leslie Cole MD

Preventative Medicine Specialist | Public Health & General Preventive Medicine

517 Northlake Blvd North Palm Beach FL, 33408

About

At St. Petersburg Health & Wellness, we believe in patient centered, individualized care. We believe in keeping you healthy by helping you understand what contributes to your wellness. Our team combines Functional, Anti-Aging, Preventive, Regenerative and Integrative Medicine to provide you the best possible outcome. Rooting out the cause of your symptoms and correcting those; optimizing your hormone, nutrition and microbiome balance; eliminating toxins and stress; etc. are your best tools. There is a better way to maintain your health & wellness with Micronutrient, Genetic, Toxin, Heavy Metal, Microbiome, Intestinal Permeability and other testing. Taking your test results together with your symptoms we use multiple modalities including diet, IV therapy, supplements, detoxification chelation, bio-identical hormone replacement, etc. to rebalance your body to its optimal function. Located in the heart of St. Petersburg, we service the entire Tampa Bay area and beyond.

Education and Training

University of Florida College of Medicien MD 1981

Board Certification

American Board Of Anti-Aging & Regenerative Medicine

American Board of Integrative Holistic Medicine

American Board of Ophthalmology

Provider Details

Male English
Dr. Edward Leslie Cole MD
Dr. Edward Leslie Cole MD's Expert Contributions
  • Is there any preventive medicine for arthritis?

    Most autoimmune arthritis conditions (Rheumatoid Arthritis, Systemic Lupus Arthritis, Psoriatic Arthritis, etc.) have at their core a deficiency of vitamin D. The current "normal" lab levels of 30-100 are inadequate to determine if you have enough vitamin D. First, the lower limit of 30 is just enough to prevent rickets in a child. It is far from the individuals optimal level, which is just that - individual. Multiple studies show that various vitamin D levels below 60 have a significant association with both autoimmune disease and cancer risk. Michael Holick, MD, who is the #2 reference on vitamin D tests done by Labcorp, has just published a paper in 2017 that recommends vitamin D intake of 5000 IU - 15,000 IU daily in normal healthy individuals with blood levels well above 100. Most patients with autoimmune disease have lower levels of vitamin D. Much research has been done on autoimmunity and vitamin D, which has revealed that many autoimmune patients have one or more mutations in their vitamin D processing proteins so they don't utilize vitamin D adequately in their immune system even with "normal" levels. Vitamin D plays a profound role in the immune system, both making it work better to attack invading organisms, but also in decreasing it from causing increased inflammation, autoimmunity & cancer risk. In addition most people with autoimmune disease, including arthritis, have high Epstein-Barr Virus (EBV) antibodies.Turns out EBV virus blocks vitamin D receptors! Get your vitamin D levels & EBV antibody levels tested. There are currently tests for vitamin D receptor gene mutations. If you can find a test for alpha-1-hydroxylase (also called CYP27b1) - the enzyme that converts your inactive vitamin D3 (the kind you take) to the active form, have it tested. Finally, have your doctor read the research about vitamin D, vitamin D processing protein mutations (SNPs), EBV and autoimmune arthritis. Les Cole, MD READ MORE

  • I have been a chain smoker for 20 years and I have recently quit. How can I prevent lung diseases?

    The Natural Killer (NK) cells of your immune system are the cells that find & kill cancer cells before they can turn into tumors. They work best under the conditions that make all cells work best. Eat a minimum of 2/3 vegetables at every meal to maximize micro-nutrients. Take a pharmaceutical grade nutriceutical multivitamin, fish oil & probiotic. Exercize 1 hour daily (turns on approximately 400 healthy genes). And most of all as per Dr. Michael Hollick, MD take up to 15,000 IU of vitamin D (make sure it has vitamin K2 with it). If you have frequent UTIs or kidney stones take less. Vitamin D has profound effects on your immune system increasing the function of your NK cells and killing early cancer. There are also NK cell activator supplements you can add after the vitamin D. 15,000 IU of vitamin D will not cause vitamin D toxicity according to Dr. Hollick. READ MORE

  • Every winter my son ends up with a nasty cold. Are there any preventive measures he can do?

    Colds are common in children. I get good results by keeping them on 5,000 IU of vitamin D daily along with a good multivitamin daily, year round. Then at the first sign of a cold I have their parents give them 10,000 IU ov vitamin A 15 mg of zinc, and Silver Hydrosol nasal spray 4 times daily at the onset of symptoms. After the first day or 2, you can usually stop, as by then the cold has generally been averted. READ MORE

  • Can cancer be prevented?

    There are many research studies that show people with low vitamin D have a higher risk of cancer as well as autoimmune disease. To prevent this increased cancer risk vitamin D is better kept near the higher range than the lower range. If there is a high frequency of cancer in your family, there may be genetic mutations in one of more of their vitamin D processing proteins such as alpha-1-hydroxylase, which converts inactive vitamin D to active vitamin D, vitamin binding protein carrying vitamin D to the cells, and the vitamin D receptor. READ MORE

Areas of expertise and specialization

Functional Medicine, Root Cause, Thyroid, Adrenal, Bio-Identical Hormones, PMS, PMDD, Multiple Sclerosis, Autoimmune, Nutritional Therapy, Cancer Support, Intravenous Therapy, IBS, IBD, Microbiome, Detoxification, Chelation for Heavy Metals, Heart Disease

Professional Memberships

  • American Academy of Anti-Aging Medicine  

Areas of research

Multiple Sclerosis, Autoimmunity, PMDD and Neurohormones, Genetic Mutations - Methylation, Vitamin D

Dr. Edward Leslie Cole MD's Practice location

St. Petersburg Health & Wellness

2100 MLK St. N. -
St. Petersburg, Fl 33704
Get Direction
New patients: 727-202-6807
Fax: 727-498-6642

1ST CHOICE PHARMACY

517 Northlake Blvd -
North Palm Beach, FL 33408
Get Direction
New patients: 561-340-3838
Fax: 270-472-8155

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ST ANTHONYS HOSPITALl

1200 SEVENTH AVE N SAINT PETERSBURG FL 33705

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ALL CHILDREN'S HOSPITAL, INCl

501 SIXTH AVENUE SOUTH SAINT PETERSBURG FL 33701

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BAYFRONT HEALTH - ST PETERSBURGl

701 6TH ST S SAINT PETERSBURG FL 33701

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PALM BEACH GARDENS MEDICAL CENTERl

3360 BURNS RD PALM BEACH GARDENS FL 33410

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WEST PALM HOSPITALl

2201 45TH ST WEST PALM BEACH FL 33407

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ST MARY'S MEDICAL CENTERl

901 45TH ST WEST PALM BEACH FL 33407

Head west on Northlake Boulevard (CR 809A) 623 ft
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