Dr. Andrew R Hoffman M.D.
Endocrinology-Diabetes | Endocrinology, Diabetes & Metabolism
3801 Miranda Ave (111) Palo Alto CA, 94304Rating
3/5
About
Dr. Andrew Hoffman practices Endocrinology in Palo Alto, CA. Dr. Hoffman specializes in preventing, diagnosing, and treating diseases related to hormone imbalance, and the bodys glands in the endocrine system. Endocrinologists are trained and certified to treat a variety of conditions, including menopause, diabetes, infertility, and thyroid disorders, among many others. Dr. Hoffman examines patients, determines means of testing, diagnoses, and decides the best treatment methods.
Education and Training
Stanford Univ Sch Of Med- Stanford Ca 1976
Stanford University School of Medicine 1976
Board Certification
Internal MedicineAmerican Board of Internal MedicineABIM- Endocrinology and Metabolism
Internal MedicineAmerican Board of Internal MedicineABIM- 1979
Provider Details
Expert Publications
Data provided by the National Library of Medicine- An imprinted PEG1/MEST antisense expressed predominantly in human testis and in mature spermatozoa.
- A methylated oligonucleotide inhibits IGF2 expression and enhances survival in a model of hepatocellular carcinoma.
- Loss of imprinting of IGF2 and H19 in osteosarcoma is accompanied by reciprocal methylation changes of a CTCF-binding site.
- Absence of a telomere maintenance mechanism as a favorable prognostic factor in patients with osteosarcoma.
- Loss of imprinting of IGF2 sense and antisense transcripts in Wilms' tumor.
- A novel orthotopic tumor model to study growth factors and oncogenes in hepatocarcinogenesis.
- CTCF binding at the insulin-like growth factor-II (IGF2)/H19 imprinting control region is insufficient to regulate IGF2/H19 expression in human tissues.
- The histone code regulating expression of the imprinted mouse Igf2r gene.
- Five weeks of insulin-like growth factor-I treatment does not alter glucose kinetics or insulin sensitivity during a hyperglycemic clamp in older women.
- Epigenetic regulation of Igf2/H19 imprinting at CTCF insulator binding sites.
- Activating and silencing histone modifications form independent allelic switch regions in the imprinted Gnas gene.
- Epigenetic regulation of the taxol resistance-associated gene TRAG-3 in human tumors.
- IGFs and aging: is there a rationale for hormone replacement therapy?
- Efficacy and tolerability of an individualized dosing regimen for adult growth hormone replacement therapy in comparison with fixed body weight-based dosing.
- Divergent patterns of telomere maintenance mechanisms among human sarcomas: sharply contrasting prevalence of the alternative lengthening of telomeres mechanism in Ewing's sarcomas and osteosarcomas.
Treatments
- Neuroendocrinology, Endocrinology
Fellowships
- Massachusetts General Hospital MA 1982
- National Institutes of Health MD 1980
Publications
- JOURL OF CELL BIOLOGYLong noncoding R-mediated intrachromosomal interactions promote imprinting at the Kcnq1 locus2014
- Nucleus (Austin, Tex.)Implications of COMT long2013
- PLOS ONEGenomic Interaction Profiles in Breast Cancer Reveal Altered Chromatin Architecture2013
- CELL STEM CELLIntrachromosomal Looping Is Required for Activation of Endogenous Pluripotency Genes during2013
- JOURL OF CELL BIOLOGYInterruption of intrachromosomal looping by CCCTC binding factor decoy proteins abrogates genomic2011
- ANLS OF INTERL MEDICINESystematic review: The safety and efficacy of growth hormone in the healthy elderly2007
- SCIENCECTCF mediates interchromosomal colocalization between Igf2/H19 and Wsb1/Nf12006
- JOURL OF CLINICAL INVESTIGATIONA methylated oligonucleotide inhibits IGF2 expression2003
- TURE GENETICSImprinting of the Angelman syndrome gene, UBE3A, is restricted to brain1997
- TUREPROMOTER-SPECIFIC IMPRINTING OF THE HUMAN INSULIN-LIKE GROWTH FACTOR-II GENE1994
- INTERTIOL JOURL OF CANCEREpigenetic reprogramming reverses the malignt epigenotype of the MMP/TIMP axis genes in tumor cells2014
- Cell cycleChromatin looping is needed for iPSC induction.2014
- PloS oneRapid and Efficient Conversion of Integration-Free Human Induced Pluripotent Stem Cells to GMP2014
- HUMAN MOLECULAR GENETICSPromoter histone H3K27 methylation in the control of IGF2 imprinting in human tumor cell lines2014
- OBESITYAbdomil Myosteatosis Is Independently Associated with Hyperinsulinemia2013
- HIGH ALTITUDE MEDICINE & BIOLOGYCyclic Hypobaric Hypoxia Improves Markers of Glucose Metabolism in Middle-Aged Men2013
- MOLECULAR CANCERGene therapy for colorectal cancer by an oncolytic adenovirus that targets loss of the insulin2012
- JOURL OF BONE AND MINERAL RESEARCHThe Association of Concurrent Vitamin D and Sex Hormone Deficiency With Bone Loss2012
- Endocrine practiceSuccessful long-term treatment of Cushing disease with mifepristone (RU486).2012
- BIOMATERIALSPromotion of the induction of cell pluripotency through metabolic remodeling by thyroid hormone2012
- JOURL OF CLINICAL DENSITOMETRYValidation of FRC, a Fracture Risk Assessment Tool2012
- JOURL OF CLINICAL ENDOCRINOLOGY & METABOLISMThyroid Function and Mortality in Older Men: A Prospective Study2012
- JOURL OF CLINICAL ENDOCRINOLOGY & METABOLISMLong-Term Surveillance of Growth Hormone Therapy2012
- JOURL OF CLINICAL ENDOCRINOLOGY & METABOLISMHigher Testosterone Levels Are Associated with Less Loss of Lean Body Mass in Older Men2011
- ENDOCRINOLOGYIGFBP-2 Enhances VEGF Gene Promoter Activity2011
- PROCEEDINGS OF THE TIOL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMOptimized clinical performance of growth hormone with an expanded genetic code2011
- JOURL OF THE AMERICAN GERIATRICS SOCIETYMortality Risk in Older Men Associated with Changes in Weight, Lean Mass, and Fat Mass2011
- CANCERPutative Tumor Suppressor miR2011
- CANCER CAUSES & CONTROLSerum 25-OH vitamin D levels and risk of developing prostate cancer in older men2010
- CANCER BIOLOGY & THERAPYTargeted tumor gene therapy based on loss of IGF2 imprinting2010
- INTERTIOL JOURL OF CANCERTargeted knockdown of Bcl2 in tumor cells using a synthetic TRAIL 3 '-UTR microR2010
- BIOMATERIALSTransient in vitro epigenetic reprogramming of skin fibroblasts into multipotent cells2010
- HUMAN MOLECULAR GENETICSLoss of IGF2 imprinting is associated with abrogation of long2010
- JOURL OF BONE AND MINERAL RESEARCHBone Mass and Strength in Older Men With Type 2 Diabetes: The Osteoporotic Fractures in Men Study2010
- ARCHIVES OF INTERL MEDICINENocturl Arrhythmias Across a Spectrum of Obstructive2009
- MOLECULAR AND CELLULAR BIOLOGYCTCF regulates allelic expression of Igf2 by orchestrating a promoter2008
- MOLECULAR ENDOCRINOLOGYA complex deoxyribonucleic acid looping configuration2008
- ANLS OF INTERL MEDICINESystematic review: The effects of growth hormone on athletic performance2008
- PLOS CLINICAL TRIALSEffects of growth hormone2007
- EMBO JOURLCorrection of aberrant imprinting of IGF2 in human tumors by nuclear transfer2006
- AMERICAN JOURL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISMEndocrine responses to acute and chronic high-altitude exposure (4,300 meters)2006
- JOURL OF CLINICAL ENDOCRINOLOGY & METABOLISMEfficacy of a long-acting growth hormone (GH) preparation in patients with adult GH deficiency2005
- HUMAN MOLECULAR GENETICSPromoter-restricted histone code2004
- HUMAN MOLECULAR GENETICSActivating and silencing histone modifications form independent allelic switch regions in the2004
- JOURL OF BIOLOGICAL CHEMISTRYAn imprinted PEG1/MEST antisense expressed predomintly in human testis and in mature spermatozoa2002
- JOURL OF CLINICAL ENDOCRINOLOGY & METABOLISMOne year of insulin-like growth factor I treatment does not affect bone density, body composition2001
- LIFE SCIENCESDELAYED INCREASE OF ADREL TH AND PNMT ACTIVITIES FOLLOWING COLD STRESS IN MOUSE1975
Experience & Accolades
- Vice Chair2004 - 2014 Academic Affairs, Department of Medicine, Stanford
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