Dr. Isaac William Browder MD
Surgeon
325 N State Of Franklin Rd 3rd Floor Johnson City TN, 37604About
Dr. Isaac Browder is a general surgeon practicing in Johnson City, TN. Dr. Browder specializes in abdominal contents including the esophagus, stomach, liver, gallbladder, pancreas and often thyroid glands. General surgeons are able to deal with almost any surgical or critical care emergency, also involving the skin or soft tissue trauma. Dr. Browder provides quality surgical service for gravely ill or injured patients and is able to respond quickly due to knowledge of various surgical procedures.
Education and Training
Tulane Univ Sch of Med, New Orleans La 1971
Tulane University of Louisiana 1971
Tulane University School of Medicine 1971
Louisiana State University School of Medicine in New Orleans
Board Certification
SurgeryAmerican Board of SurgeryABS
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Early activation of IKKbeta during in vivo myocardial ischemia.
- Glucans exhibit weak antioxidant activity, but stimulate macrophage free radical activity.
- Normal human fibroblasts express pattern recognition receptors for fungal (1-->3)-beta-D-glucans.
- Human vascular endothelial cells express pattern recognition receptors for fungal glucans which stimulates nuclear factor kappaB activation and interleukin 8 production. Winner of the Best Paper Award from the Gold Medal Forum.
- Glucan stimulates human dermal fibroblast collagen biosynthesis through a nuclear factor-1 dependent mechanism.
- Human monocyte scavenger receptors are pattern recognition receptors for (1-->3)-beta-D-glucans.
- Primary aortogastric fistula after nissen fundoplication: a case report and review of pertinent literature.
- Modulation of tissue Toll-like receptor 2 and 4 during the early phases of
- Murine models of intestinal anastomoses.
- Development of a water-soluble, sulfated (1-->3)-beta-D-glucan biological response modifier derived from Saccharomyces cerevisiae.
- NF-kappaB activation is required for the development of cardiac hypertrophy in vivo.
- At low serum glucan concentrations there is an inverse correlation between serum glucan and serum cytokine levels in ICU patients with infections.
- Blockade of MyD88 attenuates cardiac hypertrophy and decreases cardiac myocyte apoptosis in pressure overload-induced cardiac hypertrophy in vivo.
- Overexpression of TLR2 and TLR4 susceptibility to serum deprivation-induced apoptosis in CHO cells.
- Blocking the MyD88-dependent pathway protects the myocardium from ischemia/reperfusion injury in rat hearts.
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