Dr. Gregory G Germino M.D.
Nephrologist (Kidney Specialist) | Nephrology
1800 Orleans St Baltimore MD, 21287About
Dr. Gregory Germino is a nephrologist practicing in Baltimore, MD. Dr. Germino specializes in the care and treatment of the kidneys. As a nephrologist, Dr. Germino most typically treats conditions like kidney stones, chronic kidney disease, acute renal failure, polycystuc kidney disease, high blood pressure and more. Nephrologists are also experts on kidney transplantation and dialysis. They are usually referred to by primary care physicians for problems related to the kidneys, and while they can perform tests to diagnose kidney disorders, they do not perform surgeries.
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Expert Publications
Data provided by the National Library of Medicine- A 1-Mb BAC/PAC-based physical map of the autosomal recessive polycystic kidney disease gene (PKHD1) region on chromosome 6.
- Molecular basis of autosomal dominant polycystic kidney disease.
- Aberrant splicing in the PKD2 gene as a cause of polycystic kidney disease.
- Mutation detection of PKD1 identifies a novel mutation common to three families with aneurysms and/or very-early-onset disease.
- Genomic organization of the KIAA0057 gene that encodes a TRAM-like protein and its exclusion as a polycystic kidney and hepatic disease 1 (PKHD1) candidate gene.
- Genomic structure of the gene for the human P1 protein (MCM3) and its exclusion as a candidate for autosomal recessive polycystic kidney disease.
- Thirteen novel mutations of the replicated region of PKD1 in an Asian population.
- Polycystin-1, the gene product of PKD1, induces resistance to apoptosis and spontaneous tubulogenesis in MDCK cells.
- Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents.
- Bilineal disease and trans-heterozygotes in autosomal dominant polycystic kidney disease.
- Mutation analysis of the entire replicated portion of PKD1 using genomic DNA
- Biochemical characterization of bona fide polycystin-1 in vitro and in vivo.
- Expression of PKD1 and PKD2 transcripts and proteins in human embryo and during normal kidney development.
- PKHD1, the polycystic kidney and hepatic disease 1 gene, encodes a novel large protein containing multiple immunoglobulin-like plexin-transcription-factor domains and parallel beta-helix 1 repeats.
- PKD1 induces p21(waf1) and regulation of the cell cycle via direct activation of the JAK-STAT signaling pathway in a process requiring PKD2.
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