Dr. Wafik El-Deiry, MD, PhD, FACP
Oncologist | Hematology & Oncology
Brown University Providence RI, 02912About
Dr. Wafik El-Deiry is a medical oncologist licensded in Pennsylvania and Rhode Island. Dr. El-Deiry specializes in colorectal cancer, precision oncology and inherited susceptibility to cancer. Medical Oncologists work with other specialists such as surgeons, radiation therapists, pathologists and gynecologists in order to get a better understanding on the cases. Often, patients are asked to participate in clinical research that could result in more efficient treatment methods.
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Education and Training
Univ of Miami Sch of Med, Miami Fl MD 1987
Univ of Miami Sch of Med PhD 1987
Board Certification
American Board of Internal Medicine
Medical Oncology (Internal Medicine)
Provider Details
Areas of expertise and specialization
Faculty Titles & Positions
- Associate Dean for Oncologic Sciences Warren Alpert Medical School 2019 - Present
- Director, Cancer Center at Brown University Brown University 2020 - Present
- Attending Medical Oncologist Lifespan Health System 2019 - Present
- Mencoff Family University Professor Brown University 2019 - Present
- William Wikoff Smith Endowed Chair in Cancer Research Fox Chase Cancer Center 2016 - 2018
- Deputy Director for Translational Research Fox Chase Cancer Center, Philadelphia 2014 - 2018
- Professor of Medical Oncology Fox Chase Cancer Center 2014 - 2018
- Division Chief, Hematology/Oncology Penn State University 2010 - 2014
- Rose Dunlap Division Chair in Hematology/Oncology Penn State University 2014 - 2018
- Professor of Medicine (Hematology Oncology) Penn State University 2014 - 2018
- Chair WIN Consortium 2023 - Present
- American Cancer Society Research Professor -
Awards
- Excellence in Mentoring Award 2013 Department of Medicine, Penn State University
- America's Top Oncologists 2009 Consumer’s Research Council of America
- America's Top Oncologists 2008 Consumer’s Research Council of America
Professional Memberships
- American Society of Clinical Oncology
- American Association for Cancer Research
- Association of American Physicians
- American Society for Clinical Investigation
- American College of Physicians
- Johns Hopkins University Society of Scholars
Fellowships
- Johns Hopkins Hospital and the Johns Hopkins Oncology Center Medical Oncology
Charities and Philanthropic Endeavors
- American Cancer Society
- The Miriam Hospital Gala
- Tour De Rhody
- The Joan DeCotis Foundation
Areas of research
El-Deiry discovered p21(WAF1) as p53 target gene, and cell cycle inhibitor that explained the mammalian DNA-damage cellular growth-arrest response. He discovered TRAIL receptor DR5, its regulation by p53, and discovered ONC201/TIC10 as cancer therapeutic. ONC201/TIC10 has clinical efficacy in H3K27M-mutated diffuse midline-gliomas and tumors without H3K27M including neuroendocrine tumors, prostate and endometrial cancers. El-Deiry has >500 peer-reviewed publications, 6 edited-books, and his 2023 H-index=127 with >101,000 citations in Google Scholar. He is among 2023 top Molecular Biology Scientists in US (#81; https://research.com/scientists-rankings/molecular-biology/us).
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Dr. El-Deiry, a Leading Authority in Oncology, Continues to Revolutionize Cancer Treatment Strategies and Patient Care
An esteemed figure in the medical world, Dr. El-Deiry has garnered recognition for his outstanding contributions to the field of oncology. As the Associate Dean for Oncologic Sciences at the Warren Alpert Medical School and the Director of the Cancer Center at Brown University, he plays a pivotal role in shaping the future of cancer research and patient care. His leadership extends to overseeing the Joint Program in Cancer Biology, a collaborative initiative involving Brown University and affiliated hospitals, aimed at fostering interdisciplinary research and enhancing clinical outcomes.
With a distinguished background that combines medical expertise and significant research achievements, he has made remarkable strides in understanding cancer biology and developing innovative treatment approaches. Specializing in the care of patients with colorectal cancer and rare genetic drivers of other tumor types, he is a driving force in advancing oncologic sciences.
Boasting an impressive educational background that includes MD and PhD degrees from the University of Miami School of Medicine, Dr. El-Deiry completed his medical training at prestigious institutions such as the Johns Hopkins Hospital and the Johns Hopkins Oncology Center. His expertise has been further recognized through his appointment as an American Cancer Society Research Professor, solidifying his reputation as a leading expert in the oncology field.
His impactful research has led to groundbreaking discoveries in cancer biology, notably his pioneering work in defining the genomic DNA-binding consensus sequence for the p53 tumor suppressor protein. His identification of p53 target genes and the CDK inhibitor p21(WAF1) has significantly advanced our understanding of tumor suppression mechanisms and cell cycle regulation, leading to the development of FDA-approved CDK inhibitor drugs that have revolutionized cancer therapy.
Throughout his illustrious career, Dr. El-Deiry has held key positions at esteemed institutions, including the University of Pennsylvania School of Medicine, where he served as a Professor of Medicine, Pharmacology, and Genetics. His tenure as a Howard Hughes Medical Institute Investigator further underscores his exceptional contributions to biomedical research, inspiring the next generation of oncologists and researchers.
Dr. El-Deiry's relentless dedication to translating cutting-edge research into tangible clinical outcomes continues to shape the landscape of oncology, offering hope to patients and driving progress in the fight against cancer.
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