Dr. Jake Alden Kushner M.D.
Endocronologist (Pediatric) | Pediatric Endocrinology
3615 Civic Center Blvd Chop Endocrine, Arc Philadelphia PA, 19104About
Dr. Jake Kushner is leading the efforts in Diabetes and Endocrinology at Texas Children's Hospital. Dr. Kushner is a McNair Medical Institute Scholar at the Baylor College of Medicine. As the Chief of ...
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Expert Publications
Data provided by the National Library of Medicine- Pdx1 restores beta cell function in Irs2 knockout mice.
- Insulin receptor substrate-2 deficiency impairs brain growth and promotes tau phosphorylation.
- Effects of dietary glycaemic index on adiposity, glucose homoeostasis, and plasma lipids in animals.
- Dysregulation of insulin receptor substrate 2 in beta cells and brain causes obesity and diabetes.
- Insulin receptor substrate 2 is essential for maturation and survival of photoreceptor cells.
- Cyclins D2 and D1 are essential for postnatal pancreatic beta-cell growth.
- Very slow turnover of beta-cells in aged adult mice.
- Phosphatase and tensin homolog regulation of islet growth and glucose homeostasis.
- Beta-cell growth: an unusual paradigm of organogenesis that is cyclin D2/Cdk4 dependent.
- Growth and regeneration of adult beta cells does not involve specialized progenitors.
- Identification of a WD40 repeat-containing isoform of PHIP as a novel regulator of beta-cell growth and survival.
- Haematopoietic stem cells do not asymmetrically segregate chromosomes or retain BrdU.
- Irs2 inactivation suppresses tumor progression in Pten+/- mice.
- Adaptive beta-cell proliferation is severely restricted with advanced age.
- Cyclin D2 protein stability is regulated in pancreatic beta-cells.
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