![Dr. Sylvia S. Bottomley, MD, Internist](/doctor_images/5/5c/2888217.jpg?v=4d6f)
Dr. Sylvia S. Bottomley, MD
Hematologist (Blood Specialist) | Hematology
921 Ne 13th St Oklahoma City OK, 73104About
Dr. Sylvia Bottomley is a hematology internist practicing in Oklahoma City, OK. Dr. Bottomley specializes in cases of suspected blood disorders when a diagnosis is unclear and further medical care is needed. Hematology internists work with other specialists such as surgeons, radiation therapists and gynecologists in order to get a better understanding on the cases. Often, patients are asked to participate in clinical research that could result in more efficient treatment methods.
Education and Training
Univ of Ok Coll of Med, Oklahoma City Ok 1958
Board Certification
Hematology (Internal Medicine)
Internal MedicineAmerican Board of Internal MedicineABIM
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Iron deficiency due to excessive therapeutic phlebotomy in hemochromatosis.
- Diminished erythroid ferrochelatase activity in protoporphyria.
- CNS demyelination associated with copper deficiency and hyperzincemia.
- Anemia: diagnosis and therapy.
- 5-Aminolevulinic acid synthase: mechanism, mutations and medicine.
- Pyridoxine-responsive anemia.
- Refractory anemias with siderosis.
- PATHOGENESIS OF COMMON ANEMIAS.
- The major splice variant of human 5-aminolevulinate synthase-2 contributes significantly to erythroid heme biosynthesis.
- Myelopathy due to copper deficiency.
- Congenital sideroblastic anemias.
- X-linked sideroblastic anemia associated with a novel ALAS2 mutation and unfortunate skewed X-chromosome inactivation patterns.
- Iron overload and prolonged ingestion of iron supplements: clinical features and mutation analysis of hemochromatosis-associated genes in four cases.
- Analysis of mitochondrial DNA in 104 patients with myelodysplastic syndromes.
- Mutations in mitochondrial carrier family gene SLC25A38 cause nonsyndromic autosomal recessive congenital sideroblastic anemia.
Areas of expertise and specialization
Awards
- Physician of the Year in Academic Medicine 1987 University of Oklahoma College of Medicine Alumni Association
- James F. Hammarsten Physician of Excellence Award 1995 Oklahoma City VA Medical Center
- Research Lifetime Achievement Award 2003 Oklahoma City VA Medical Center
Professional Memberships
- Phi Kappa Phi
Fellowships
- Hematology Fellowship at University of Oklahoma Heaalth Sciences Center
What do you attribute your success to?
- Hard work, good luck, family support
Areas of research
- Sideroblastic anemias, iron overload disorders, porphyrias
Favorite Place to Vacation
- Colorado
Hobbies / Sports
- Skiing, listening to music, reading
Favorite professional publications
- Chapters in Wintrobe's Clinical Hematology text - in 6 editions
Areas of research
Sideroblastic anemias
Iron overload disorders
Porphyrias
Dr. Sylvia S. Bottomley, MD's Practice location
Practice At 921 Ne 13th St
921 Ne 13th St -Oklahoma City, OK 73104Get Direction
Dr. Sylvia S. Bottomley, MD's reviews
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Nearest Hospitals
O U MEDICAL CENTERl
700 NE 13TH STREET OKLAHOMA CITY OK 73104ST ANTHONY HOSPITALl
1000 NORTH LEE AVENUE OKLAHOMA CITY OK 73101INTEGRIS SOUTHWEST MEDICAL CENTERl
4401 SOUTH WESTERN AVENUE OKLAHOMA CITY OK 73109O U MEDICAL CENTERl
700 NE 13TH STREET OKLAHOMA CITY OK 73104ST ANTHONY HOSPITALl
1000 NORTH LEE AVENUE OKLAHOMA CITY OK 73101INTEGRIS SOUTHWEST MEDICAL CENTERl
4401 SOUTH WESTERN AVENUE OKLAHOMA CITY OK 73109