Albert Russell La spada
Pathologist | Anatomic Pathology & Clinical Pathology
7920 Frost St Suite 200 San Diego CA, 92123About
Dr. Albert La spada is a pathologist practicing in San Diego, CA. Dr. La spada is a doctor who specializes in the study of bodily fluids and tissues. As a pathologist, Dr. La spada can help your primary care doctor make a diagnosis about your medical condition. Dr. La spada may perform a tissue biopsy to determine if a patient has cancer, practice genetic testing, and complete a number of laboratory examinations. Pathologists can also perform autopsies which can determine a persons cause of death and gain information about genetic progression of a disease.
Education and Training
Perelman School of Medicine University of Pennsylvania 1993
Perelman School of Medicine at the University of Pennsylvania 1993
Board Certification
Medical GeneticsAmerican Board of Medical GeneticsABMG
PathologyAmerican Board of PathologyABP
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Late-onset SCA2: 33 CAG repeats are sufficient to cause disease.
- In vivo expansion of trinucleotide repeats yields plasmid and YAC constructs for targeting and transgenesis.
- Genomic organization, chromosome location, and expression analysis of mouse beta-synuclein, a candidate for involvement in neurodegeneration.
- Polyglutamine-expanded ataxin-7 antagonizes CRX function and induces cone-rod dystrophy in a mouse model of SCA7.
- Purkinje cell degeneration (pcd) phenotypes caused by mutations in the axotomy-induced gene, Nna1.
- Polyglutamine-expanded ataxin-7 promotes non-cell-autonomous purkinje cell degeneration and displays proteolytic cleavage in ataxic transgenic mice.
- Polyglutamine and transcription: gene expression changes shared by DRPLA and Huntington's disease mouse models reveal context-independent effects.
- Genomic context drives SCA7 CAG repeat instability, while expressed SCA7 cDNAs are intergenerationally and somatically stable in transgenic mice.
- Polyglutamines placed into context.
- Insights into the molecular basis of polyglutamine neurodegeneration from studies of a spinocerebellar ataxia type 7 mouse model.
- Polyglutamines stop traffic: axonal transport as a common target in neurodegenerative diseases.
- Interference of Crx-dependent transcription by ataxin-7 involves interaction between the glutamine regions and requires the ataxin-7 carboxy-terminal region for nuclear localization.
- Androgen receptor YAC transgenic mice recapitulate SBMA motor neuronopathy and implicate VEGF164 in the motor neuron degeneration.
- Dynamic mutations on the move in Banff.
- Beta-synuclein gene alterations in dementia with Lewy bodies.
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