Dr. Jonathan Patrick Wiebe M.D.
Internist
11303 W WASHINGTON BLVD STE 100 LOS ANGELES CA, 90066About
Dr. Jonathan Wiebe is an internist practicing in Los Angeles, CA. Dr. Wiebe specializes in the medical treatment of adults. Internists can act as a primary physician or a consultant to a primary physician. They manage both common and rare diseases. Dr. Wiebe provides comprehensive care and manages treatment with surgeons as well. Internists establish long-term relationships with their patients and incorporate disease prevention and mental health care into their practice.
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Antinociceptive effects of the neuroactive steroid, 3alpha-hydroxy-5alpha-pregnan-20-one and progesterone in the land snail, Cepaea nemoralis.
- The 4-pregnene and 5alpha-pregnane progesterone metabolites formed in nontumorous
- Plasma membrane receptors for the cancer-regulating progesterone metabolites, 5alpha-pregnane-3,20-dione and 3alpha-hydroxy-4-pregnen-20-one in MCF-7 breast cancer cells.
- The endogenous progesterone metabolite, 5a-pregnane-3,20-dione, decreases cell-substrate attachment, adhesion plaques, vinculin expression, and polymerized F-actin in MCF-7 breast cancer cells.
- Sertoli cells from immature rats : in vitro stimulation of steroid metabolism by FSH.
- Steroidogenesis in rat leydig cells: changes in activity of 5-ane and 5-ene 3beta-hydroxysteroid dehydrogenases during sexual maturation.
- Steroidogenesis in rat leydig cells: changes in activity of 5-ane and 5-ene 3beta-hydroxysteroid dehydrogenases during sexual maturation.
- Glycerol alters cytoskeleton and cell adhesion while inhibiting cell proliferation.
- The role of progesterone metabolites in breast cancer: potential for new diagnostics and therapeutics.
- Membrane 5alpha-pregnane-3,20-dione (5alphaP) receptors in MCF-7 and MCF-10A breast cancer cells are up-regulated by estradiol and 5alphaP and down-regulated by the progesterone metabolites, 3alpha-dihydroprogesterone and 20alpha-dihydroprogesterone,
- Rat sertoli cells: a rapid method for obtaining viable cells.
- Rat sertoli cells: a rapid method for obtaining viable cells.
- Dutasteride affects progesterone metabolizing enzyme activity/expression in human breast cell lines resulting in suppression of cell proliferation and detachment.
- Regulation of estrogen receptor (ER) levels in MCF-7 cells by progesterone metabolites.
- Inhibition of cell proliferation by glycerol.
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