Dr. Matthew Kent Topham M.D.
Internist
2000 Circle Of Hope Dr Room 5363 Salt Lake City UT, 84112About
Dr. Matthew Topham is an internist practicing in Salt Lake City, UT. Dr. Topham specializes in the medical treatment of adults. Internists can act as a primary physician or a consultant to a primary physician. They manage both common and rare diseases. Dr. Topham provides comprehensive care and manages treatment with surgeons as well. Internists establish long-term relationships with their patients and incorporate disease prevention and mental health care into their practice.
Education and Training
Univ of Ut Sch of Med, Salt Lake Cty Ut 1992
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Mammalian diacylglycerol kinases, a family of lipid kinases with signaling functions.
- Diacylglycerol kinase zeta regulates Ras activation by a novel mechanism.
- Interaction of gamma 1-syntrophin with diacylglycerol kinase-zeta. Regulation of nuclear localization by PDZ interactions.
- Physiological implications of the contrasting modulation of the activities of the epsilon- and zeta-isoforms of diacylglycerol kinase.
- Regulation of T cell receptor-induced activation of the Ras-ERK pathway by diacylglycerol kinase zeta.
- Association of diacylglycerol kinase zeta with protein kinase C alpha: spatial regulation of diacylglycerol signaling.
- Protein kinase C alpha phosphorylates and negatively regulates diacylglycerol kinase zeta.
- Diacylglycerol kinase-zeta localization in skeletal muscle is regulated by phosphorylation and interaction with syntrophins.
- Diacylglycerol kinase zeta regulates phosphatidylinositol 4-phosphate 5-kinase Ialpha by a novel mechanism.
- Diacylglycerol kinases.
- Lipid modulation of the activity of diacylglycerol kinase alpha- and zeta-isoforms: activation by phosphatidylethanolamine and cholesterol.
- The alpha isoform of diacylglycerol kinase exhibits arachidonoyl specificity with alkylacylglycerol.
- Diacylglycerol kinase iota regulates Ras guanyl-releasing protein 3 and inhibits Rap1 signaling.
- Regulation of neurite outgrowth in N1E-115 cells through PDZ-mediated recruitment of diacylglycerol kinase zeta.
- The retinoblastoma family proteins bind to and activate diacylglycerol kinase zeta.
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