Dr. Thomas R Kleyman MD
Doctor
3550 Terrace Street Scaife Hall, Suite A Pittsburgh PA, 15261About
Dr. Thomas R Kleyman MD is a top Doctor in Pittsburgh, PA. With a passion for the field and an unwavering commitment to their specialty, Dr. Thomas R Kleyman MD is an expert in changing the lives of their patients for the better. Through their designated cause and expertise in the field, Dr. Thomas R Kleyman MD is a prime example of a true leader in health care. As a leader and expert in their field, Dr. Thomas R Kleyman MD is passionate about enhancing patient quality of life. They embody the values of communication, safety, and trust when dealing directly with patients. In Pittsburgh, PA, Dr. Thomas R Kleyman MD is a true asset to their field and dedicated to the profession of medicine.
Education and Training
Washington Univ Sch Of Med- St Louis Mo 1978
Board Certification
Internal MedicineAmerican Board of Internal MedicineABIM
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Antiidiotypic antibody recognizes an amiloride binding domain within the alpha subunit of the epithelial Na+ channel.
- Cloning and functional expression of the mouse epithelial sodium channel.
- Association of the epithelial sodium channel with Apx and alpha-spectrin in A6 renal epithelial cells.
- Mechanism of action of amiloride: a molecular prospective.
- Characterization of the selectivity filter of the epithelial sodium channel.
- Epithelial sodium channels regulate cystic fibrosis transmembrane conductance regulator chloride channels in Xenopus oocytes.
- Epithelial sodium channel pore region. structure and role in gating.
- Flow-dependent K+ secretion in the cortical collecting duct is mediated by a maxi-K channel.
- Epithelial Na(+) channels are regulated by flow.
- Second transmembrane domains of ENaC subunits contribute to ion permeation and selectivity.
- Genistein restores functional interactions between Delta F508-CFTR and ENaC in Xenopus oocytes.
- Functional effects of a monoclonal antibody on mechanoelectrical transduction in outer hair cells.
- Phosphatase inhibitors increase the open probability of ENaC in A6 cells.
- External nickel inhibits epithelial sodium channel by binding to histidine residues within the extracellular domains of alpha and gamma subunits and reducing channel open probability.
- Asymmetric organization of the pore region of the epithelial sodium channel.
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