Dr. Curtis J. Wray, MD, MS
Surgical Oncologist | Surgical Oncology
6500 W. Loop South 200-E Houston TX, 77401About
Curtis J. Wray, MD, MS, FACS, attended the University of Louisville and received an undergraduate degree in Chemistry. He received his medical degree from the University of Kentucky College of Medicine in 1998. Dr. Wray completed the general surgery residency program at the University of Cincinnati in 2005. While at Cincinnati, he received an NIH T32 postdoctoral research fellowship. From 2005-2008, Dr. Wray completed a surgical oncology fellowship at the University of Texas M.D. Anderson Cancer Center.
In 2008, Dr. Wray was appointed Assistant Professor of Surgery at McGovern Medical School at UTHealth Houston. His research interests include clinical outcomes for gastrointestinal cancers as well as cancer-related healthcare disparities. These research efforts have led to 52 peer-reviewed publications. This work led to a successful application and grant funding from the American Cancer Society to investigate clinical outcomes for Hepatocellular Cancer patients. In 2013, Dr. Wray was promoted to Associate Professor of Surgery at McGovern Medical School at UTHealth Houston. He recently received a Masters’s Degree in Clinical Research from McGovern Medical School at UTHealth Houston.
Dr. Wray belongs to numerous professional organizations, including the Society of Surgical Oncology, American College of Surgeons, American Association of Cancer Research, Society of University Surgeons, American Society of Clinical Oncology, Society for Surgery of the Alimentary Tract, Association for Academic Surgery and the American Hepatico-Pancreatico-Biliary Association. Dr. Wray has served as Cancer Liaison Physician for Harris Health System and was recently appointed to the American College of Surgeons Commission on Cancer. Currently, he is President of the Houston Surgical Society. Areas of clinical expertise include traditional open as well as minimally invasive surgery for gastric, liver, pancreas, and colorectal cancers.
Education and Training
University of Kentucky MD 1998
McGovern Medical School MS 2016
Board Certification
SurgeryAmerican Board of SurgeryABS
Provider Details
Dr. Curtis J. Wray, MD, MS's Expert Contributions
Pancreatic Cancer Treatment
Pancreatic cancer remains a lethal diagnosis. The 5-year survival rate is less than 15%. For patients with resectable disease, neoadjuvant chemotherapy (e.g. chemotherapy before surgery) is associated with improved survival. Current chemotherapy protocols include modified Folfirinox or...
Adrenal Tumor?
The answer depends upon the size of the adrenal tumor. If less than 4 cm, most often these are monitored with ct scan or MRI over several months. If the adrenal tumor is functional (e.g. it is secreting too much of a specific hormone) than it should be considered for removal. READ MORE
Is liver resection done under general anesthesia?
Yes. Liver surgery is performed with the patient under general anesthesia. READ MORE
How serious is pancreas surgery?
Pancreas surgery is a major abdominal operation and is challenging due to locations and proximity to other structures. It it located behind the stomach and in close proximity to several key vascular structures. However, surgery with an experienced surgeon and hospital system can lessen the risk associated with pancreas surgery. READ MORE
What treatment is best for stage 1 colon cancer?
Surgery to remove the affected portion of the colon is the most effective for early, stage 1 colon cancer. READ MORE
Expert Publications
Data provided by the National Library of Medicine- Expression and binding activity of the glucocorticoid receptor are upregulated in septic muscle.
- Interposition of a jejunal segment as an alternative one-stage operation for acute left colon obstruction.
- Insulin-like growth factor-I inhibits lysosomal and proteasome-dependent proteolysis in skeletal muscle after burn injury.
- IL-1beta stimulates IL-6 production in cultured skeletal muscle cells through activation of MAP kinase signaling pathway and NF-kappa B.
- Superinduction of IL-6 by cycloheximide is associated with mRNA stabilization and sustained activation of p38 map kinase and NF-kappaB in cultured caco-2 cells.
- Colon cancer angiogenesis and antiangiogenic therapy.
- Treatment of cultured myotubes with the calcium ionophore A23187 increases proteasome activity via a CaMK II-caspase-calpain-dependent mechanism.
- The relationship of lymph node dissection and colon cancer survival in the Veterans Affairs Central Cancer Registry.
- Pancreatic adenocarcinoma in a patient with situs inversus: a case report of this rare coincidence.
- Modified Makuuchi incision for foregut procedures.
- Hepatocellular carcinoma survival in uninsured and underinsured patients.
- Clinical implications of DNA methylation in hepatocellular carcinoma.
- Unretrieved gallstone mimicking an intra-abdominal soft tissue mass.
- Cytomegalovirus enteritis manifesting as recurrent bowel obstruction and jejunal perforation in patient with acquired immunodeficiency syndrome: rare report of survival and review of the literature.
- Relationship between documentation status and survival for medically underserved Hispanic breast cancer patients.
Areas of expertise and specialization
Faculty Titles & Positions
- Professor of Surgery UTHealth Houston 2021 - Present
Professional Memberships
- American College of Surgeons
Fellowships
- University of Texas M D Anderson Cancer Center
Areas of research
Pancreatic Cancer
Radiofrequency Ablation
Dr. Curtis J. Wray, MD, MS's Practice location
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Dr. Curtis J. Wray, MD, MS's reviews
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Get to know Surgical Oncologist Dr. Curtis J. Wray, who serves patients throughout the State of Texas.
A devoted surgical oncologist, Dr. Wray is affiliated with UT Physicians, working with patients at UTMIST – Bellaire Station, UT Memorial Hermann Cancer Center – Texas Medical Center, and UT Physicians – Sugar Land.
His expertise in surgical techniques is vast and diverse. He possesses expertise in both open and minimally invasive surgery for gastric, liver, pancreas, and colorectal cancers. Moreover, his commitment to utilizing cutting-edge technology is evident in his proficiency with robotic surgery for GI cancers. Notably, in 2018, he initiated a robotic pancreas surgery program at Memorial Hermann TMC, further enhancing the treatment options available to patients.
One of Dr. Wray’s significant achievements was the groundbreaking robotic Whipple (pancreaticoduodenectomy) procedure, which he and his colleagues performed in June 2019, using the daVinci Xi robotic surgical system at Memorial Hermann-Texas Medical Center.
Born with a passion for science, he pursued his academic journey at the University of Louisville, where he obtained an undergraduate degree in chemistry. However, his true calling lay in medicine, which led him to the University of Kentucky College of Medicine, where he earned his medical degree in 1998.
Following his medical studies, Dr. Wray embarked on a rigorous journey to refine his surgical skills. He completed the general surgery residency program at the prestigious University of Cincinnati in 2005, where his dedication and aptitude for research were rewarded with an NIH T32 postdoctoral research fellowship. It was during this time that his interest in cancer research began to flourish, inspiring him to pursue a surgical oncology fellowship at the esteemed University of Texas M.D. Anderson Cancer Center from 2005 to 2008.
Furthermore, he pursued his quest for knowledge by obtaining a master’s degree in clinical research from UTHealth, solidifying his expertise in cancer research and clinical outcomes.
With an unwavering commitment to his specialty, the doctor is board-certified in surgical oncology and general surgery by the American Board of Surgery (ABS). The ABS is an independent, non-profit organization located in Philadelphia, Pennsylvania, founded for the purpose of certifying surgeons who have met a defined standard of education, training, and knowledge.
Remaining up to date in his field, Dr. Wray is an active member of the Society of Surgical Oncology, the American College of Surgeons, the American Association of Cancer Research, the Society of University Surgeons, the American Society of Clinical Oncology, the Society for Surgery of the Alimentary Tract, the Association for Academic Surgery, and the American Hepato-Pancreato-Biliary Association.
Beyond his impressive academic and research endeavors, he has actively served in various capacities within healthcare institutions and organizations. In particular, he has been a cancer liaison physician for Harris Health System, actively contributing to the improvement of cancer care in the community. He was also appointed to the American College of Surgeons Commission on Cancer, where he continues to influence policy and practice in cancer care.
Surgical oncology is the branch of surgery applied to oncology. It focuses on the surgical management of tumors, especially cancerous tumors. A surgical oncologist removes the tumor and nearby tissue during surgery. He or she also performs certain types of biopsies to help diagnose cancer.
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