Dr. Joseph A. Bellanti, MD

Expert Publications

• A clinical perspective of cystic fibrosis and new genetic findings: relationship of CFTR mutations to genotype-phenotype manifestations.
• Developmental immunology: clinical application to allergy-immunology.
• IgE and non-IgE food allergy.
• Abnormalities of Th1 function in non-IgE food allergy, celiac disease, and ileal lymphonodular hyperplasia: a new relationship?
• Immunologic studies of specific mucosal and systemic immune responses in Mexican school children after booster aerosol or subcutaneous immunization with measles vaccine.
• Gastrointestinal immunopathology and food allergy.
• Current epidemiology of asthma: emerging patterns of asthma.
• A phase I study of the safety of honeybee venom extract as a possible treatment for patients with progressive forms of multiple sclerosis.
• Recurrent infections and joint pain.
• Literature review: the best new articles in the specialty of allergy, asthma, and immunology, 2004-2005.
• Immunization update and hot topics in clinical immunology: how does this relate to my practice?
• Atopic disease, immune system, and the environment.
• Clinical reactivity to ingestion challenge with mixed mold extract may be enhanced in subjects sensitized to molds.
• Adverse reactions to vaccines.
• Egg allergy and influenza vaccination.

Media Releases

Get to know Allergist / Immunologist Dr. Joseph A. Bellanti, who serves patients in Washington, D.C. 

Dr. Bellanti is a board-certified allergist and immunologist who serves as the Director of the International Center for Interdisciplinary Studies of Immunology (ICISI) at Georgetown University Medical Center and as a Professor of Pediatrics and Microbiology-Immunology, (Emeritus) at Georgetown University School of Medicine in Washington, D.C.

A native of Buffalo, Dr. Bellanti earned his medical degree from the Jacobs School of Medicine and Biomedical Sciences, University at Buffalo in 1958.  Following completion of a residency at the Children’s Hospital of Buffalo in 1961, he was accepted into a National Institutes of Health-supported postdoctoral fellowship in a developmental immunology training program at the University of Florida in 1961 under the direction of Richard T. Smith, MD, a pioneering pediatric immunologist and disciple of Robert A. Good, MD (1961-62). He later continued his postdoctoral studies as a Research Virologist at Walter Reed Army Institute of Research in Washington, D.C. (1962-65), where among his many research contributions with his colleagues was the seminal description of secretory IgA antiviral principle of respiratory secretions. In 1963, he joined the faculty of Georgetown University School of Medicine as an Assistant Professor of Pediatrics and Microbiology, where he rose to his current position of Professor of Pediatrics and Microbiology-Immunology in 1970.

Soon after arriving at Georgetown, Dr. Bellanti realized that his goal of generating new knowledge in immunology and translating it to clinical use would require adopting a multidisciplinary translational approach to immunology that would involve a horizontal matrix including both basic and clinical investigators, allied health professionals, statisticians, health educators, and the public. Accordingly, in 1975, he established and became the Director of the International Center for Interdisciplinary Studies of Immunology at Georgetown University Medical Center and later Director of the Division of Allergy-Immunology, Department of Pediatrics and the Division of Virology and Immunology in the Department of Laboratory Medicine of Georgetown University Hospital. 

With a passion for his field and an unwavering commitment to his specialty, the doctor has focused a major investigative effort on antimicrobial research, evaluation of new vaccine strategies, and developmental immunology. Together with other investigators, he has studied antibody and phagocytic cell function in the newborn human and in experimental model systems. He and his colleagues described the antiviral activity of the secretory IgA system in respiratory secretions and later cellular responses to viral infections following immunization or natural infection. A major collaborative effort with Mexican colleagues was directed to the study of protective immune responses to measles vaccine administration via the nasal route, a technique originally pioneered by Dr. Albert B. Sabin, one of Dr. Bellanti’s scientific teachers and collaborators.

Drawing upon his ground-breaking experience as an established clinical investigator in the field of translational research in immunology, Dr. Bellanti’s academic career has been nurtured by his previous research that has focused on the immunopathogenesis of infectious diseases and allergic and autoimmune disorders. His experience as a GUMC clinical investigator was established by a track record of successfully directing major R01, Center and Program Project awards, as well as training grants. In addition to teaching medical students and residents, he directed a postgraduate training program in developmental immunology from 1968-1996 and a clinical residency program in allergy and immunology from 1978 -1992from which over 270 graduates received training.

The most recent phase of Dr. Bellanti’s research has been directed to studies exploring the role of epigenetic mechanisms in the control of gene expression related to Treg function, an important governing mechanism of immune system function.  Together with active collaboration with basic science colleagues, he continues making scientific contributions in critical areas of DNA methylation as a controlling mechanism of gene expression which are finding clinical application in the allergic diseases, the autoimmune disorders and cancer. 

Dr, Bellanti’s leadership role is exemplified by the many professional and scientific positions on which he has served. These include the American Board of Allergy and Immunology, a conjoint board of the American Board of Internal Medicine and the American Board of Pediatrics, from 1975 to 1980. He also served as the Board’s president from 1979 to 1980. He is past-President of the Society for Pediatric Research (1980), InterAsma (1987-90), the American College of Allergy, Asthma & Immunology (ACAAI, 1991-92), and the Association of Medical Laboratory Immunologists (AMLI, 1992-93). His editorial positions include Editor-in-Chief of Pediatric Research from 1975 -1983, Editor-in-Chief of Annals of Allergy from 1982-1990, and Editor-in-Chief Allergy, Asthma Proceedings from 2004 until present.

Frequently, Dr. Bellanti lectures abroad in Europe and South America, sometimes in fluent Spanish or Italian. He is the recipient of numerous honors and awards, including the E. Mead Johnson Award for Excellence in Pediatric Research (1970); the Outstanding Educators of America Award of the William Peck Society (1972), the Humanitarian Award from the American College of Allergy and Immunology for “excellence and service and teaching of clinical immunology” in 1974; and the Distinguished Fellow Award in 1981. In 1998, he received the Distinguished Medical Alumnus Award from the State University of Buffalo. He is also the recipient of three honorary degrees: Honoris causa degrees from the University of Palermo (1992) and Georgetown University (2002), and the CEA Universidad San Pablo, Madrid, Spain (2015).

Among his many accolades, Dr. Bellanti has published more than 500 scientific articles and abstracts, as well as numerous textbook chapters. His widely acclaimed textbooks in immunology include the fourth edition, “Immunology IV: Clinical Applications in Health and Disease”, which was published in English in 2012 and in Spanish in 2016. In addition to the printed version, both are available online with creative illustrations, animations, and interactive Q&As in every chapter and both are available on the following hyperlink: https://www.immunologycenter.org/en/special-pricing 

The field of allergy and immunology involves the management of disorders related to the immune system. These conditions range from the very common to the very rare, spanning all ages and encompassing various organ systems. An allergist and immunologist is a physician specially trained to diagnose, treat, and manage allergies, asthma, and immunologic disorders, including primary immunodeficiency.

Recommended Articles

• What is Lyme Disease? A General Overview of the Disease

  Lyme disease is a tick-borne infectious disease. It is caused by a spiral shaped bacterium known as borrelia burgdorferi sensu lato. A common tick is the carrier of this bacterium.The first incidence of lyme disease was reported in 1975 in a town called Old Lyme in Connecticut. Lyme disease is the...

• Top 12 Natural Home Remedies for Urinary Tract Infection (UTI)

  What is a urinary tract infection (UTI)?A urinary tract infection (UTI) is an infection in the urinary system, which includes the kidneys, bladder, urethra, and ureters. Usually, UTIs happen in the lower urinary tract, which consists of the bladder and urethra.Women are more prone to developing...

• Treatments for Asthma

  Asthma has somehow evaded the most probing research ever conducted, and still defies a permanent cure. What we can do is manage its symptoms as efficiently as possible and prevent the condition from ruining our lives....

• What Is Pyrexia: Causes, Symptoms, and Treatment

  Introduction Pyrexia is the medical term for fever, in which the human body temperature rises above the average normal (37 degrees Celsius or 98.6 degrees Fahrenheit). Pyrexia is one of the most common symptoms of numerous medical conditions.There are multiple factors can affect the normal body...

• Questions You Should Be Asking Your Doctor

  IntroductionAlthough doctors have the best intentions, it does not always mean that they will perfectly recognize their patient’s greatest need. For this reason, patients also need to take an active role when it comes to communicating with their doctor.One of the best ways to make sure that...

• Anemia Symptoms

  What is anemia?Anemia occurs when there are low levels of red blood cells (RBCs) in the body. Red blood cells are the ones that carry oxygen all over the body. So when a person's RBC count is lower than normal, it means that there is not enough oxygen in the blood, causing symptoms of anemia, such...