Dr. Ignacio R Rodriguez MD
Neurologist | Neurology
8757 Georgia Avenue 430 Silver Spring MD, 20910About
Dr. Ignacio Rodriguez is a distinguished Neurologist in Silver Spring, MD. Dr. Rodriguez specializes in diagnosing, treating, and managing disorders of the brain and nervous system. With expertise in handling complex conditions like epilepsy, multiple sclerosis, and migraines, Dr. Rodriguez employs advanced techniques and personalized treatment plans to improve patient outcomes. As a neurologist, Dr. Rodriguez is committed to staying abreast of the latest developments in neurological research and therapies.
Education and Training
U of Tx Med Sch At Houston, Houston Tx 1976
University Of Texas Medical School at Houston 1976
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Rapid analysis of oxysterols by HPLC and UV spectroscopy.
- RPE cells internalize low-density lipoprotein (LDL) and oxidized LDL (oxLDL) in large quantities in vitro and in vivo.
- Cytotoxicity of oxidized low-density lipoprotein in cultured RPE cells is dependent on the formation of 7-ketocholesterol.
- Expression and localization of sterol 27-hydroxylase (CYP27A1) in monkey retina.
- Uptake of cholesterol by the retina occurs primarily via a low density lipoprotein receptor-mediated process.
- Intraretinal lipid transport is dependent on high density lipoprotein-like particles and class B scavenger receptors.
- Peroxiredoxin 3 (PDRX3) is highly expressed in the primate retina especially in blue cones.
- Retinoic acid regulates the human methionine sulfoxide reductase A (MSRA) gene via two distinct promoters.
- Photodamage generates 7-keto- and 7-hydroxycholesterol in the rat retina via a free radical-mediated mechanism.
- Methionine sulfoxide reductase B2 is highly expressed in the retina and protects retinal pigmented epithelium cells from oxidative damage.
- Sterculic acid antagonizes 7-ketocholesterol-mediated inflammation and inhibits choroidal neovascularization.
- 7-Ketocholesterol-induced inflammation signals mostly through the TLR4 receptor both in vitro and in vivo.
- Extra-hepatic metabolism of 7-ketocholesterol occurs by esterification to fatty acids via cPLA2α and SOAT1 followed by selective efflux to HDL.
- Inflammasomes Induced by 7-Ketocholesterol and Other Stimuli in RPE and in Bone Marrow-Derived Cells Differ Markedly in Their Production of IL-1β and IL-18.
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