Dr. Mark M Moasser M.D.
Oncologist | Medical Oncology
1600 Divisadero St 2nd Floor, Box 1710 San Francisco CA, 94115About
Dr. Mark Moasser is a medical oncologist specializing in breast cancer treatment and research. In the laboratory, he works to develop more effective therapies for the treatment of breast cancer and designs ...
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Inhibition of heat shock protein 90 function by ansamycins causes the morphological and functional differentiation of breast cancer cells.
- Oral gossypol in the treatment of patients with refractory metastatic breast cancer: a phase I/II clinical trial.
- The tyrosine kinase inhibitor ZD1839 ("Iressa") inhibits HER2-driven signaling and suppresses the growth of HER2-overexpressing tumor cells.
- The use of molecular markers in farnesyltransferase inhibitor (FTI) therapy of breast cancer.
- A novel pyridopyrimidine inhibitor of abl kinase is a picomolar inhibitor of Bcr-abl-driven K562 cells and is effective against STI571-resistant Bcr-abl mutants.
- Resistance to gefitinib in PTEN-null HER-overexpressing tumor cells can be overcome through restoration of PTEN function or pharmacologic modulation of constitutive phosphatidylinositol 3'-kinase/Akt pathway signaling.
- S-phase inhibition of cell cycle progression by a novel class of pyridopyrimidine tyrosine kinase inhibitors.
- Adhesion signaling by a novel mitotic substrate of src kinases.
- Escape from HER-family tyrosine kinase inhibitor therapy by the kinase-inactive HER3.
- The oncogene HER2: its signaling and transforming functions and its role in human cancer pathogenesis.
- Targeting the function of the HER2 oncogene in human cancer therapeutics.
- Targeting HER proteins in cancer therapy and the role of the non-target HER3.
- Improved tumor vascular function following high-dose epidermal growth factor receptor tyrosine kinase inhibitor therapy.
- The HER family and cancer: emerging molecular mechanisms and therapeutic targets.
- The epidermal growth factor receptor family: biology driving targeted therapeutics.
Clinical Trials
Fellowships
- Memorial Sloan - Kettering Cancer Center 1995
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