Dr. Fadi George Lakkis M.D.
Nephrologist (Kidney Specialist) | Nephrology
W1548 Biomedical Science Tower 200 Lothrop Street Pittsburgh PA, 15261Rating
4/5
About
Dr. Fadi Lakkis is a nephrologist practicing in Pittsburgh, PA. Dr. Lakkis specializes in the care and treatment of the kidneys. As a nephrologist, Dr. Lakkis most typically treats conditions like kidney stones, chronic kidney disease, acute renal failure, polycystuc kidney disease, high blood pressure and more. Nephrologists are also experts on kidney transplantation and dialysis. They are usually referred to by primary care physicians for problems related to the kidneys, and while they can perform tests to diagnose kidney disorders, they do not perform surgeries.
Board Certification
Internal MedicineAmerican Board of Internal MedicineABIM
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Interferon-gamma is necessary for initiating the acute rejection of major histocompatibility complex class II-disparate skin allografts.
- Regulation of alloantigen-mediated T-cell proliferation by endogenous interferon-gamma: implications for long-term allograft acceptance.
- Increased susceptibility to immunologically mediated glomerulonephritis in IFN-gamma-deficient mice.
- The role of the common cytokine receptor gamma-chain in regulating IL-2-dependent, activation-induced CD8+ T cell death.
- The role of cytokines, CTLA-4 and costimulation in transplant tolerance and rejection.
- Interleukin-4 and interleukin-13 act on glomerular visceral epithelial cells.
- The alloimmune response and effector mechanisms of allograft rejection.
- Immunologic 'ignorance' of vascularized organ transplants in the absence of secondary lymphoid tissue.
- Alloantigen-driven T cell death mediated by Fas ligand and tumor necrosis factor-alpha is not essential for the induction of allograft acceptance.
- The dual role of IL-2 in the generation and maintenance of CD8+ memory T cells.
- A scenic overlook on the road to clinical tolerance.
- Failure to induce neonatal tolerance in mice that lack both IL-4 and IL-13 but not in those that lack IL-4 alone.
- Gene expression analysis in human renal allograft biopsy samples using high-density oligoarray technology.
- Cutting edge: Secondary lymphoid organs are essential for maintaining the CD4, but not CD8, naive T cell pool.
- Recall and propagation of allospecific memory T cells independent of secondary lymphoid organs.
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