Dr. Rajesh R Nair M.D
Hematologist-Oncologist | Hematology & Oncology
2115 S Fremont Ave Suite 1000 Springfield MO, 65804About
Dr. Rajesh Nair is a hematologist oncologist practicing in Springfield, MO. Dr. Nair specializes in the diagnosis, treatment and prevention of blood diseases such as anemia, hemophilia, sickle-cell disease, leukemia and lymphoma. Hematologist Oncologists are also trained in the study of cancer and its attack on other organs.
Board Certification
Internal MedicineAmerican Board of Internal MedicineABIM
Provider Details
Expert Publications
Data provided by the National Library of Medicine- A bisanthracycline (WP631) represses uPAR gene expression and cell migration of RKO colon cancer cells by interfering with transcription factor binding to a chromatin-accessible -148/-124 promoter region.
- Expression cloning identifies transgelin (SM22) as a novel repressor of 92-kDa type IV collagenase (MMP-9) expression.
- A novel high-throughput screening system identifies a small molecule repressive for matrix metalloproteinase-9 expression.
- Stat3 contributes to resistance toward BCR-ABL inhibitors in a bone marrow microenvironment model of drug resistance.
- Signaling networks associated with BCR-ABL-dependent transformation.
- HYD1-induced increase in reactive oxygen species leads to autophagy and necrotic cell death in multiple myeloma cells.
- The bone marrow microenvironment as a sanctuary for minimal residual disease in CML.
- Acquisition of resistance toward HYD1 correlates with a reduction in cleaved α4 integrin expression and a compromised CAM-DR phenotype.
- Potentiation of Nilotinib-mediated cell death in the context of the bone marrow microenvironment requires a promiscuous JAK inhibitor in CML.
- Role of STAT3 in Transformation and Drug Resistance in CML.
- MTI-101 (cyclized HYD1) binds a CD44 containing complex and induces necrotic cell death in multiple myeloma.
- Nail-patella syndrome-a novel mutation in the LMX1B gene.
- Stable and Potent Selenomab-Drug Conjugates.
- Actinomycin D Down-regulates SOX2 Expression and Induces Death in Breast Cancer Stem Cells.
Treatments
- Prostate Cancer
- Melanoma
- Anemia
- Osteoporosis
- Breast Cancer
- Kidney Cancer
- Lung Cancer
- Colon Cancer
- Acute Myeloid Leukemia (aml)
- Lymphoma
- Multiple Myeloma
- Leukemia
- Extra Corporeal Shockwave Therapy
Fellowships
- Saint Louis University Hospital - Hematology/Oncology
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