Dr. Dean D. Metcalfe M.D.
Rheumatologist | Rheumatology
Nih 10 Center Dr 10/11c207 Bethesda MD, 20892About
Dr. Dean Metcalfe is a rheumatologist practicing in Bethesda, MD. Dr. Metcalfe specializes in the treatment of musculoskeletal diseases and systematic autoimmune conditions that can affect the bones, muscles or bones. Eventually, if not treated, these illnesses can also impact the skin, eyes, nervous system and internal organs. Dr. Metcalfe treats diseases similar to orthopedists but does not perform surgery. Often times, research is conducted to find potential alternatives for the patients illness.
Board Certification
Allergy and ImmunologyAmerican Board of Allergy and ImmunologyABAI
Internal MedicineAmerican Board of Internal MedicineABIM- Rheumatology
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Mast cells express connexins on their cytoplasmic membrane.
- Mast cell migratory response to interleukin-8 is mediated through interaction with chemokine receptor CXCR2/Interleukin-8RB.
- Murine mast cells exposed to mercuric chloride release granule-associated N-acetyl-beta-D-hexosaminidase and secrete IL-4 and TNF-alpha.
- Eotaxin potentiates antigen-dependent basophil IL-4 production.
- Receptor-mediated modulation of murine mast cell function by alpha-melanocyte stimulating hormone.
- Mast cell-T cell interactions.
- Demonstration that human mast cells arise from a progenitor cell population that is CD34(+), c-kit(+), and expresses aminopeptidase N (CD13).
- Frequency and characterization of antigen-specific IL-4- and IL-13- producing basophils and T cells in peripheral blood of healthy and asthmatic subjects.
- Demonstration that platelet-activating factor is capable of activating mast cells and inducing a chemotactic response.
- Human mast cells express the hyaluronic-acid-binding isoform of CD44 and adhere to hyaluronic acid.
- Analysis of the surface expression of c-kit and occurrence of the c-kit Asp816Val
- Mastocytosis complicating pregnancy.
- Mast cells in innate immunity.
- Differential diagnosis of the patient with unexplained flushing/anaphylaxis.
- Expression of a functional high-affinity IgG receptor, Fc gamma RI, on human mast cells: Up-regulation by IFN-gamma.
Dr. Dean D. Metcalfe M.D.'s Practice location
Dean Metcalfe
Nih 10 Center Dr 10/11c207 -Bethesda, MD 20892Get Direction
Dr. Dean D. Metcalfe M.D.'s reviews
Write ReviewRecommended Articles
![]()
Fibromyalgia May Have a Connection to Rheumatoid ArhritisThe latest research indicates that fibromyalgia and rheumatoid arthritis often coexist due to a variety of different reasons. They have some similarities in their genetic background, and females are more prone to both of them. Chronic stress also plays an important role with the development of these...
![]()
Foods to Eat if You Have Rheumatoid ArthritisWhat is rheumatoid arthritis? Rheumatoid arthritis is a progressive inflammatory disorder that can result in swollen and painful joints. There are no particular types of bacteria or types of viruses that cause this disease, because the culprit is the person's own immune system. The condition occurs...
![]()
Are There Risks to a Spinal Stenosis Surgery?Like any other surgical procedure, spinal stenosis surgery has its own risks and possible complications. However, if performed correctly by professional medical staff, the possibility of any complication after the surgery is low.The potential risks and possible complications following a spinal...
![]()
Tips: Managing Your Morning Stiffness with Rheumatoid ArthritisIf you are living with rheumatoid arthritis (RA), then you are likely familiar with stiff joints, particularly in the morning. And you are not alone. Recent reports show that around 90% of individuals with active RA who are not experiencing active RA. ...
![]()
Fibromyalgia: Change Your LifestyleLifestyle ChangesLong-term body pain and localized tenderness, as well as the many other symptoms of fibromyalgia can drastically change the lifestyle of an individual. It can affect a person’s mobility resulting in the need for a cane, walker or wheelchair. Individuals may also find that they...
![]()
Nick Cannon Discusses Feeling Guilty After Lupus FlaresEven though patients change their lifestyle, have a good diet, and exercise daily, they still may not experience any change in their chronic illness. The guilt that follows an unsuccessful change can be enormous for those with a chronic illness, and celebrities are not immune to this guilt as well. ...
Nearby Providers
![]()
Dr. Richard Wilson M.D.1647 Benning Rd NE Washington DC 20002![]()
Xiaochun Zhang Other2102 D Gallows Rd Vienna VA 22182![]()
Dr. Sharon Michelle Dowell MBBS2041 Georgia Ave Nw Washington DC 20060![]()
Dr. Shari B Diamond M.D.2021 K St Nw Washington DC 20006![]()
Dr. Jerome J Schnapp M.D.7300 Hanover Dr #201 Greenbelt MD 20770![]()
Dr. Ellen M Jenkins MD3022 Williams Dr Fairfax VA 22031
Nearest Hospitals
SIBLEY MEMORIAL HOSPITALl
5255 LOUGHBORO RD NW WASHINGTON DC 20016HOLY CROSS HOSPITALl
1500 FOREST GLEN ROAD SILVER SPRING MD 20910SUBURBAN HOSPITALl
8600 OLD GEORGETOWN ROAD BETHESDA MD 20814