Dr. Brett Graham MD, PHD
Pediatrician
550 UNIVERSITY BLVD INDIANAPOLIS IN, 46202About
Clinical Interests - Genetic Disorders and Metabolic Disorders. We are utilizing mouse embryonic stem (ES) cells that contain gene trap mutations in genes known to cause mitochondrial disease in human ...
Education and Training
Emory University School Of Medicine 1998
Board Certification
Medical GeneticsAmerican Board of Medical GeneticsABMG- Medical Biochemical Genetics
PediatricsAmerican Board of PediatricsABP
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Noninvasive, in vivo approaches to evaluating behavior and exercise physiology in mouse models of mitochondrial disease.
- The physiological properties of a novel family of VDAC-like proteins from Drosophila melanogaster.
- Genetic approaches to analyzing mitochondrial outer membrane permeability.
- Mitochondrial voltage-dependent anion channel gene family in Drosophila melanogaster: complex patterns of evolution, genomic organization, and developmental expression.
- Ménage-à-trois 1 is critical for the transcriptional function of PPARgamma coactivator 1.
- Fine-Lubinsky syndrome: sibling pair suggests possible autosomal recessive
- Intrauterine growth retardation and placental vacuolization as presenting features in a case of GM1 gangliosidosis.
- The mitochondrial 13513G>A mutation is associated with Leigh disease phenotypes independent of complex I deficiency in muscle.
- Genetic strategies for dissecting mammalian and Drosophila voltage-dependent anion channel functions.
- Two mtDNA mutations 14487T>C (M63V, ND6) and 12297T>C (tRNA Leu) in a Leigh syndrome family.
- Activin signaling: effects on body composition and mitochondrial energy metabolism.
- A syndrome of short stature, microcephaly and speech delay is associated with duplications reciprocal to the common Sotos syndrome deletion.
- Neurologic dysfunction and male infertility in Drosophila porin mutants: a new model for mitochondrial dysfunction and disease.
- Current molecular diagnostic algorithm for mitochondrial disorders.
- Structures and molecular mechanisms for common 15q13.3 microduplications involving CHRNA7: benign or pathological?
Professional Memberships
- Member American Society of Human Genetics
- Member Society of Inherited Metabolic Disorders
- Member Society for the Study of Inborn Errors of Metabolism
Fellowships
- Baylor College of Medicine, Molecular & Human Genetics 2003
- Molecular Genetics, Baylor College of Medicine, Houston, TX
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