Dr. Jesse E. Otero, MD
Orthopedist | Adult Reconstructive Orthopaedic Surgery
250 N Caswell Rd Suite 200A Charlotte NC, 28204About
Dr. Jesse Otero is an orthopaedic surgeon practicing in Charlotte, NC. Dr. Otero specializes in the diagnosis, treatment and rehabilitation of injuries, diseases and disorders of the hip and knee. As an arthroplasty specialist, Dr. Otero performs hip and knee replacement surgery. He specializes in robotic surgery, minimally invasive surgery, and revision surgery. He also has a special interest in taking care of patients with infection of the hip and knee joint.
Education and Training
Washington University M.D. 2011
Stanford University BS Biology 2004
Washington University in St. Louis School of Medicine MD, PhD 2011
Board Certification
American Board of Orthopaedic Surgery
MD License North Carolina - #2016-00057 - Active
MD License Iowa – #MD-43916 - Inactive
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Defective osteoclastogenesis by IKKbeta-null precursors is a result of receptor activator of NF-kappaB ligand (RANKL)-induced JNK-dependent apoptosis and impaired differentiation.
- IKKbeta activation is sufficient for RANK-independent osteoclast differentiation and osteolysis.
- Tyrosine phosphorylation is required for IkappaB kinase-beta (IKKbeta) activation
- Constitutively active canonical NF-κB pathway induces severe bone loss in mice.
- Swarm rat chondrosarcoma cells as an in vivo model: lung colonization and effects of tissue environment on tumor growth.
- Ubiquitin-like domain of IKKβ regulates osteoclastogenesis and osteolysis.
- Osteoclast inhibition impairs chondrosarcoma growth and bone destruction.
Areas of expertise and specialization
Faculty Titles & Positions
- Director of Hip and Knee Research OrthoCarolina Research Institute 2019 - Present
- Clinical Associate Professor Wake Forest School of Medicine 2020 - Present
- Research Assistant Palo Alto Veterans Affairs Hospital 2002 -
- Doctoral Candidate Medical Scientist Training Program – Washington University in St. Louis School of Medicine – Laboratory of Yousef Abu-Amer 2006 - 2009
- Orthopaedic Surgery Resident University of Iowa Hospitals and Clinics 2011 - 2016
- Orthopaedic Surgeon and Clinical Fellow Adult Hip and Knee Reconstruction OrthoCarolina, Charlotte 2016 - 2017
- Assistant Professor Orthopaedic Surgery in Adult Hip and Knee Reconstruction – Department of Orthopaedic Surgery - University of Iowa Hospitals and Clinics 2017 - 2019
- Associate Professor OrthoCarolina Hip and Knee Center, Atrium Health Musculoskeletal Institute 2019 - Present
- Teaching Assistant Washington University Medical School Curriculum 2006 -
Awards
- • Stanford Undergraduate Research Organization Fellowship (HHMI) 2003
- • Palo Alto Institute for Research and Education Grant 2002 – 2004 Year
- • Honors Distinction - Bachelors in Biological Sciences 2004 Stanford University
- • MD/PhD Candidate Year Medical Scientist Training Program Washington University 2005 – 2011
- • American Society for Bone and Mineral Research Young Investigator Travel Grant 2007
- • American Society for Bone and Mineral Research Young Investigator Award 2009
- • AΩA Medical Honor Society 2010
- • The Dr. John Esben Kirk Award for Scholastic Achievement in Medical School 2011
- • Selected participant AAOS ORS OREF Clinician Scholar Career Development Program 2013
- • Mid-America Orthopaedic Association Education Grant for Senior Residents 2016
- • Best Paper Award – One versus Two Stage Treatment for Prosthetic Joint Infection: A Prospective, Randomized Clinical Trial 2024 American Association of Hip and Knee Surgeons. Annual Meeting
- • Top Paper Award – Hip – One versus Two Stage Treatment for Prosthetic Joint Infection: A Prospective, Randomized Clinical Trial 2024 American Academy of Orthopaedic Surgeons Annual Meeting
- • Best Paper 2024 – One versus Two Stage Treatment for Prosthetic Joint Infection: A Prospective, Randomized Clinical Trial 2024 American Academy of Orthopaedic Surgeons Annual Meeting
Professional Memberships
- American Academy of Orthopaedic Surgeons
- American Association of Hip and Knee Surgeons
- Musculoskeletal Infection Society Member
- Reviewer - Journal of Arthroplasty
- Reviewer – Journal of Bone and Joint Surgery
- Reviewer – Journal of Bone and Joint Infection
- AAHKS Research Committee – 2017- Presen
- American Joint Replacement Registry Research Publications Committee - 2020 - present
Fellowships
- OrthoCarolina Adult Hip and Knee Reconstruction 2017
Charities and Philanthropic Endeavors
- Charlotte Area Habitat for Humanity
- Care Ring
Internships
- University of Iowa Hospitals and Clinics
Fellowships
- OrthoCarolina, Adult Hip & Knee Reconstruction - Fellowship
Professional Society Memberships
- American Academy of Orthopaedic Surgeons, Resident Member American Association of Hip and Knee Surgeons, Arthroplasty Surgeon in Training, Reviewer - Journal of Arthroplasty, Reviewer Journal of Bone and Joint Surgery, Reviewer Journal of Bone and Joint Surgery Reviews, Member AAHKS Research Committee 2017- Present
Articles and Publications
- more than 8- publications as he does lots of research
What do you attribute your success to?
- He attributes his success to his biggest driving force which are his patients and in his ability to be able to help them get out of pain and back on their feet again. He found his calling in the medical field while he was in college, as he had a lot of great mentors that helped guide him into the direction in which he found his calling as an orthopedic surgeon. He became the first in his family to become a doctor and he enjoys reading the Medical Journal of Bone and Joint Surgery and Journal of Arthroplasty in his spare time as he always works hard to ensure his patients that he is up to date with the latest advances so that he can treat them with the best of the best care that he can offer.
Teaching and speaking
- Attending Atrium Orthopedic residencyAttending OrthoCarolina Adult Hip and Knee Reconstruction Fellowship
Areas of research
Joint Replcement Outcomes
Periprosthetic Joint Infection
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Media Releases
Bringing Expertise in Advanced Orthopedic Techniques to OrthoCarolina Hip and Knee Center
A former fellow at OrthoCarolina, Dr. Otero brings a wealth of knowledge and expertise in adult hip and knee reconstruction to its esteemed Hip and Knee Center, having completed his residency in orthopedic surgery at the prestigious University of Iowa Hospitals and Clinics. He earned his medical degree from Washington University in St. Louis School of Medicine, establishing a strong foundation in orthopedic care.
In his clinical role, he specializes in a range of advanced procedures, including anterior hip replacement, total hip arthroplasty, and robotic-assisted knee surgeries. His commitment to patient-centered care is evident in his dedication to providing comprehensive treatment options for those suffering from hip and knee conditions. He also has significant experience in complex joint reconstruction, revision surgeries, and addressing prosthetic joint infections, making him a valuable addition to the OrthoCarolina team.
In his ongoing pursuit of excellence, Dr. Otero is actively involved in professional organizations. As a fellow of the American Academy of Orthopaedic Surgeons and member of the American Association of Hip and Knee Surgeons, he is committed to staying at the forefront of orthopedic advancements. Additionally, he serves as a reviewer for several renowned medical journals, including the Journal of Arthroplasty and the Journal of Bone and Joint Surgery, contributing to the ongoing dialogue and research in the field.
Dedicated to teaching and leadership within the orthopedic community, he is a faculty member in the Atrium Health orthopaedic residency program, and he trains fellows in adult hip and reconstruction at the OrthoCarolina Hip and Knee Center.. His involvement in these teaching activities demonstrates his commitment to fostering the next generation of orthopedic surgeons and promoting diversity within the field.
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