Dr. Stephen B Howell M.D.
Oncologist | Medical Oncology
3855 Health Sciences Dr Mail Code 0819 La Jolla CA, 92093About
Dr. Stephen Howell is an oncologist practicing in La Jolla, CA. Dr. Howell specializes in the care and treatment of patients with cancer. As an oncologist, Dr. Howell manages and oversees the treatment of a cancer patient after he or she has been diagnosed with the disease. Oncologists will care for their patients throughout the course of the disease. Types of oncologists include medical oncologists, surgical oncologists, radiation oncologists, gynecologic oncologists, pediatric oncologists and hematologist oncologists.
Education and Training
Harvard Medical School, Boston, Ma Medical Degree
Massachusetts General Hospital, Boston, MA Other Degree
Dana Farber Cancer Institute, Boston, MA Other Degree
Professor of Medicine Medical Degree
Board Certification
Internal MedicineAmerican Board of Internal MedicineABIM
Internal MedicineAmerican Board of Internal MedicineABIM- Medical Oncology
Provider Details
Expert Publications
Data provided by the National Library of Medicine- An open label trial of sustained-release cytarabine (DepoCyt) for the intrathecal treatment of solid tumor neoplastic meningitis.
- Intraperitoneal therapy for stage III ovarian cancer: a therapy whose time has come!
- The copper transporter CTR1 regulates cisplatin uptake in Saccharomyces cerevisiae.
- Identification of transdominant-negative genetic suppressor elements derived from hMSH2 that mediate resistance to 6-thioguanine.
- Acquisition of resistance to cisplatin is accompanied by changes in the cellular pharmacology of copper.
- Diazonamide A and a synthetic structural analog: disruptive effects on mitosis and cellular microtubules and analysis of their interactions with tubulin.
- The copper export pump ATP7B modulates the cellular pharmacology of carboplatin in ovarian carcinoma cells.
- Cross-resistance to cisplatin in cells with acquired resistance to copper.
- Increase in expression of the copper transporter ATP7A during platinum drug-based treatment is associated with poor survival in ovarian cancer patients.
- A Phase I and pharmacological study of the platinum polymer AP5280 given as an intravenous infusion once every 3 weeks in patients with solid tumors.
- Modulation of the cellular pharmacology of cisplatin and its analogs by the copper exporters ATP7A and ATP7B.
- The copper influx transporter human copper transport protein 1 regulates the uptake of cisplatin in human ovarian carcinoma cells.
- Confocal microscopic analysis of the interaction between cisplatin and the copper transporter ATP7B in human ovarian carcinoma cells.
- Increased expression of the copper efflux transporter ATP7A mediates resistance to cisplatin, carboplatin, and oxaliplatin in ovarian cancer cells.
- cDNA microarray-based identification of genes and pathways associated with oxaliplatin resistance.
Dr. Stephen B Howell M.D.'s Practice location
Stephen Howell
3855 Health Sciences Dr Mail Code 0819 -La Jolla, CA 92093Get Direction
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