Thomas Floyd Osborne MD
Radiologist | Diagnostic Radiology
781 Vista Point Cir Vista CA, 92084About
Dr. Thomas Osborne is a radiologist practicing in Vista, CA. Dr. Osborne specializes in diagnosing and treating injuries and diseases using medical imaging techniques such as X-Rays, magnetic resonance imaging and computed tomography exams. These techniques offer accurate visibility to the inside of the patients body and help to detect otherwise hidden illnesses so that they can be treated quickly and efficiently.
Board Certification
RadiologyAmerican Board of RadiologyABR- Neuroradiology
Provider Details
Expert Publications
Data provided by the National Library of Medicine- A critical role for cAMP response element-binding protein (CREB) as a Co-activator in sterol-regulated transcription of 3-hydroxy-3-methylglutaryl coenzyme A synthase promoter.
- Co-stimulation of promoter for low density lipoprotein receptor gene by sterol regulatory element-binding protein and Sp1 is specifically disrupted by the yin yang 1 protein.
- Different sterol regulatory element-binding protein-1 isoforms utilize distinct co-regulatory factors to activate the promoter for fatty acid synthase.
- Nutrient regulation of gene expression by the sterol regulatory element binding proteins: increased recruitment of gene-specific coregulatory factors and selective hyperacetylation of histone H3 in vivo.
- Sterol regulatory element-binding proteins (SREBPs): key regulators of nutritional homeostasis and insulin action.
- Conditional response of the human steroidogenic acute regulatory protein gene promoter to sterol regulatory element binding protein-1a.
- Transcriptional regulation of the murine acetyl-CoA synthetase 1 gene through multiple clustered binding sites for sterol regulatory element-binding proteins and a single neighboring site for Sp1.
- CREating a SCAP-less liver keeps SREBPs pinned in the ER membrane and prevents increased lipid synthesis in response to low cholesterol and high insulin.
- Red 25, a protein that binds specifically to the sterol regulatory region in the promoter for 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
- NF-I proteins from brain interact with the proenkephalin cAMP inducible enhancer.
- Single nucleotide resolution of sterol regulatory region in promoter for 3-hydroxy-3-methylglutaryl coenzyme A reductase.
- Identification of nucleotides responsible for enhancer activity of sterol regulatory element in low density lipoprotein receptor gene.
- Multiple sterol regulatory elements in promoter for hamster 3-hydroxy-3-methylglutaryl-coenzyme A synthase.
- Multiple genes encode nuclear factor 1-like proteins that bind to the promoter for 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
- Purification of a protein doublet that binds to six TGG-containing sequences in the promoter for hamster 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
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