Dr. Kwame Anyane-Yeboa, MD
Geneticist | Clinical Genetics (M.D.)
1000 10th Ave Suite 11a-Genetics New York NY, 10019About
Dr. Kwame Anyane-Yeboa practices Genetic Medicine in New York, NY. As a geneticist, Dr. Anyane-Yeboa performs experiments and analyzes data to interpret the inheritance of different traits in patients. A geneticist evaluates, diagnoses, and manages patients with hereditary conditions or congenital malformations, genetic risk calculations, and mutation analysis. Dr. Anyane-Yeboa carries out studies, tests, and counsels patients with genetic diseases.
Dr. Kwame Anyane-Yeboa, MD's Videos
Education and Training
University of Ghana / Medical School 1972
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Dr. Kwame Anyane-Yeboa, MD's Expert Contributions
Are all congenital disorders inherited?
Congenital muscular dystrophies are genetic but not always inherited. Most cases are inherited either from one parent or both parents. When it is from both parents, each of them carries one copy of an abnormal gene but are healthy. The affected child, male or female has 2 copies of the abnormal gene, one from each parents. Carrier parents are healthy and there will not be a family history of the condition in either side of the family. However parents have 1 in 4 chance in each pregnancy of having another affected child. In other situations the condition is inherited from an affected parent who has 50% chance of having another affected child with each pregnancy. The most common type of congenital muscular dystrophy called Duchenne muscular dystrophy is inherited from an asymptomatic Carrie mother and affects 50% of her sons. In about 1/3 of Duchenne dystrophy the gene is not carried by the mom but is a new mutation that appears for the 1st time in the son. Recurrence is very low for mothers sons in future pregnancies in that situation. Most of these conditions can be diagnosed by neurologist and geneticists with a combination of muscle biopsies and genetic testing of the affected child and parents. Recurrence can only be determined when a definitive genetic diagnosis has been made and parents adequately tested. Kwame Anyane-Yeboa MD READ MORE
Are there ways to test for Down syndrome?
There are very good ways of screening for Down syndrome. Best is through mother’s blood in early pregnancy. Contact your Obstetrician early in pregnancy so the test can be done for you. Taste is called NIPT- noninvasive prenatal test. Kwame Anyane-Yeboa READ MORE
Why does depression have a genetic factor?
There are strong genetic factors in depression, bipolar disease, and schizophrenia not all of which have been completely clarified as yet. There is a lot of ongoing research worldwide to better understand those genetic factors which hopefully may lead to better treatment or cure for some cases. Kwame Anyane-Yeboa READ MORE
How accurate are DNA kits like 23andMe?
Good for Ancestry determination. Not for health related issues. READ MORE
What are the various factors that cause cystic fibrosis?
Most frequent symptoms of CF are recurrent pulmonary and sinus infections. There are over 1800 genetic mutations in the CF gene. Severity of condition depends on which 2 mutations are passed to that individual. An individual with CF inherits 1 copy of the mutation from each parent. Late detection suggests that the mutations are most likely mutations that cause mild disease. Mutations can be detected by genetic testing. READ MORE
Is 23andMe accurate?
Ancestral history is accurate but not reliable for health information. READ MORE
Is there a way to understand if my child has any genetic issue during pregnancy?
There are now non-invasive genetic tests for early pregnancy, which are done with the mother's blood. These tests are screening tests, but highly accurate to detect Down syndrome and some other severe chromosome abnormalities. If positive, CVS or amniocentesis can be done for confirmation. READ MORE
What are the chances that my child will have sickle cell anemia?
The chance that your baby would have Sickle cell anemia is 25% (1 in 4). Sickle cell anemia can be detected in pregnancy by testing a piece of the placenta obtained through a procedure called CVS or amniocentesis. Both procedures, although invasive, are associated with minimal risk for a miscarriage. READ MORE
My son died of cystic fibrosis when he was a teenager. Is it possible for his brother to get it too?
Yes, cystic fibrosis is a very common genetic disorder. An affected individual has 2 mutations in the CF gene. Each gene is contributed from each parent. The risk that the fetus you carry could be born with CF if from the same father is 25%. If the father is different, he needs to be tested to find out if he carries a CF mutation. Genetic testing is available in pregnancy, and can be arranged for you by your obstetrician. READ MORE
Do I have to go to a geneticist for genetic testing?
Ask your physician to refer you to a genetic center for consultation with a genetic counselor who specializes in testing people at risk for cancer to determine your risk, and what test is available for the cancer in your family. READ MORE
Can doctors identify congenital heart disease while the baby is in the womb?
Yes, most congenital heart disease can be detected with ultrasound from about 14 weeks or earlier. Note that not all heart diseases are detected in pregnancy. Mild types the involve the the septum (curtain separating the left side of the heart from the right) may sometimes be difficult to detect in pregnancy. READ MORE
What conditions does gene therapy treat?
Currently gene therapy is very limited to a few conditions on research basis, however there is a lot of research going on with the technique called gene editing. This technology has potential to provide gene therapy in the future. If you are interested to know more about specific government-sponsored research for gene therapy visit www.clinicaltrials.gov. READ MORE
My daughter is going for genetic testing. What should I expect?
You will first meet with a genetic counselor who will take your family history and draw a pedigree (family tree), and then see a genetics doctor who will examine you doctor and determine the the best genetic tests available for your daughter. Sometimes genetic tests may not be indicated. Your daughter's symptoms will decide the genetic tests that should be performed. READ MORE
Can leukemia be genetic?
If you brother's leukemia was not linked to a genetic disease, the risk to his child would be negligible. If linked to a genetic disorder the nature of the disorder will determine the risk for his unborn child. READ MORE
What are the causes of congenital heart diseases?
Most congenital heart disease has a hereditary component. Most parents with children born with congenital heart disease have no history of congenital heart disease, but carry silent genes which can be passed to a child. Multiple mutated genes are required to cause congenital heart disease. In most cases the risk that a 2nd baby would be born with with heart disease is quite low-about 2-3% depending on the type of heart disease. Parents who were themselves born with heart disease have a much high recurrence, depending on the type of heart disease. Most heart disease is detectable in pregnancy with ultrasonography. READ MORE
Can diabetes cause heart failure?
Yes, poorly controlled diabetes can cause heart failure. READ MORE
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Get to know Pediatrician and Clinical Geneticist Dr. Kwame Anyane-Yeboa, who serves patients in New York, New York.
Dr. Yeboa is a board-certified pediatrician and clinical geneticist who has dedicated his career to the care of children and adults with genetic disorders, as well as pregnant women with concerns about the health of their children. He serves as a Professor of Pediatrics and Interim Director of the Division of Clinical Genetics, Department of Pediatrics at NewYork-Presbyterian/Columbia University Irving Medical Center in New York City, New York. He can also be found on staff at Morgan Stanley Children’s Hospital of NewYork-Presbyterian, a pediatric hospital located in New York City.
The doctor’s major expertise is in elucidating the underlying molecular basis for complex and very often rare, genetic disorders. Through his research, he has identified several previously undescribed, or inadequately described, genetic syndromes.
In the early days of his academic career, Dr. Yeboa earned his medical degree from the University of Ghana Medical School. Upon relocating to the United States, he completed his residency in pediatrics at Harlem Hospital Center. This was followed by a fellowship in medical genetics at Columbia University Vagelos College of Physicians and Surgeons.
Following his education, he became board-certified in pediatrics by the American Board of Pediatrics, an independent, nonprofit organization whose certification is recognized throughout the world as a credential signifying a high level of physician competence. He also earned board certification in clinical genetics by the American Board of Medical Genetics and Genomics, whose mission is to serve the public and the medical profession by promoting and assuring standards of excellence in medical genetics.
Pediatrics is the branch of medicine that involves the medical care of infants, children, and adolescents. As a pediatrician, Dr. Yeboa examines, diagnoses, and treats children of all ages with a wide variety of injuries and illnesses. He understands that children change rapidly and they must be approached with an appreciation for their stage of physical and mental development.
Medical genetics is the branch of medicine that involves the diagnosis and management of hereditary disorders. Clinical geneticists are medical doctors who specialize in treating and diagnosing conditions that have a genetic origin.
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