Dr. Thomas D Meek M.D.
Neurosurgeon
511 N Alleghaney Ave Odessa TX, 79761About
Dr. Thomas Meek practices Neurological Surgery in Odessa, TX. As a Neurological Surgeon, Dr. Meek prevents, diagnoses, evaluates, and treats disorders of the autonomic, peripheral, and central nervous systems. Neurological Surgeons are trained to treat such disorders as spinal canal stenosis, herniated discs, tumors, fractures, and spinal deformities, among many others.
Education and Training
Oh State Univ Coll of Med, Columbus Oh 1961
Board Certification
Neurological SurgeryAmerican Board of Neurological SurgeryABNS
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Mechanism of inhibition of cathepsin K by potent, selective 1, 5-diacylcarbohydrazides: a new class of mechanism-based inhibitors of thiol proteases.
- Identification of a novel aspartic protease (Asp 2) as beta-secretase.
- ASP1 (BACE2) cleaves the amyloid precursor protein at the beta-secretase site.
- Steady-state kinetic characterization of substrates and metal-ion specificities of the full-length and N-terminally truncated recombinant human methionine aminopeptidases (type 2).
- Inhibitors of HIV-1 protease.
- Use of protein unfolding studies to determine the conformational and dimeric stabilities of HIV-1 and SIV proteases.
- Solvent isotope partitioning: a new kinetic tool for the determination of desorption rates of reactant water from enzyme-substrate complexes in proteases.
- Human immunodeficiency virus type 1 protease inhibitors irreversibly block infectivity of purified virions from chronically infected cells.
- Kinetic and chemical mechanisms of the fabG-encoded Streptococcus pneumoniae beta-ketoacyl-ACP reductase.
- Drug-target residence time and its implications for lead optimization.
- Chemical mechanism of a cysteine protease, cathepsin C, as revealed by integration of both steady-state and pre-steady-state solvent kinetic isotope effects.
- Purification and biochemical characterization of recombinant simian immunodeficiency virus protease and comparison to human immunodeficiency virus type 1 protease.
- Human immunodeficiency virus-1 protease. 2. Use of pH rate studies and solvent kinetic isotope effects to elucidate details of chemical mechanism.
- Adaptation of the plasma renin radioimmunoassay for use with HIV-1 protease.
- Kinetic mechanism and rate-limiting steps of focal adhesion kinase-1.
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