Dr. Jason T Yustein M.D., PH.D.
Hematologist (Pediatric) | Pediatric Hematology-Oncology
14 N Chester St Baltimore MD, 21231About
Dr. Yustein's research interests include furthering the biological, molecular and genetic understanding of pediatric sarcomas, including osteosarcoma and Ewing's sarcoma, through the formation of nove ...
Board Certification
PediatricsAmerican Board of PediatricsABP- Pediatric Hematology-Oncology
DermatologyAmerican Board of DermatologyABD
Provider Details
Expert Publications
Data provided by the National Library of Medicine- KFC, a Ste20-like kinase with mitogenic potential and capability to activate the SAPK/JNK pathway.
- Comparative studies of a new subfamily of human Ste20-like kinases: homodimerization, subcellular localization, and selective activation of MKK3 and p38.
- Poly(ADP-ribose) polymerase 1 and Ste20-like kinase hKFC act as transcriptional repressors for gamma-2 herpesvirus lytic replication.
- High ALDH activity identifies chemotherapy-resistant Ewing's sarcoma stem cells that retain sensitivity to EWS-FLI1 inhibition.
- The adolescent and young adult with cancer: state of the art -- bone tumors.
- NKD2, a negative regulator of Wnt signaling, suppresses tumor growth and metastasis in osteosarcoma.
- Cross-species identification of a plasma microRNA signature for detection, therapeutic monitoring, and prognosis in osteosarcoma.
- Coamplification of Myc/Pvt1 and homozygous deletion of Nlrp1 locus are frequent genetics changes in mouse osteosarcoma.
- Loss of Runx2 sensitises osteosarcoma to chemotherapy-induced apoptosis.
- Glycolysis determines dichotomous regulation of T cell subsets in hypoxia.
- Secreted Frizzled-Related Protein 2 (sFRP2) promotes osteosarcoma invasion and metastatic potential.
- miR-130b directly targets ARHGAP1 to drive activation of a metastatic CDC42-PAK1-AP1 positive feedback loop in Ewing sarcoma.
- Detection of Plasma MicroRNA Signature in Osteosarcoma Patients.
- Metabolic modulation of Ewing sarcoma cells inhibits tumor growth and stem cell properties.
- Tyrosine kinase expression profiles of chicken erythro-progenitor cells and oncogene-transformed erythroblasts.
Treatments
- Cancer, Blood Disorders
Professional Memberships
- Member American Academy of Pediatrics
- Member American Society for Pediatric Hematology/Oncology,
Fellowships
- Pediatric Hematology and Oncology, Johns Hopkins University Hospital, Baltimore, MD Pediatric
- Johns Hopkins School of Medicine, Hematology-Oncology 2008
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