Dr. Joseph S Pagano MD
Infectious Disease Specialist | Infectious Disease
101 Manning Dr Chapel Hill NC, 27599About
Dr. Joseph Pagano is an infectious disease specialist practicing in Chapel Hill, NC. Dr. Pagano specializes in infections that are difficult to diagnose or unresponsive to treatments, such as HIV or airborne infections from a foreign country. Infectious disease specialists usually work with conditions that are not treatable by a primary physician but it is important to keep contact with the primary physician in order to receive information about the patients history and for deciding which diagnostic tests are appropriate.
Board Certification
Internal MedicineAmerican Board of Internal MedicineABIM- Infectious Disease- 1990
Internal MedicineAmerican Board of Internal MedicineABIM- 2000
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Phosphorylation of the Epstein-Barr virus (EBV) DNA polymerase processivity factor EA-D by the EBV-encoded protein kinase and effects of the L-riboside benzimidazole 1263W94.
- Structure and function of IRF-7.
- Viruses and lymphomas.
- Epstein-barr virus latent membrane protein 1 induces and causes release of fibroblast growth factor-2.
- New associations of human papillomavirus, Simian virus 40, and Epstein-Barr virus with human cancer.
- Epstein-Barr virus induces invasion and metastasis factors.
- Interferon regulatory factor 7 regulates expression of Epstein-Barr virus latent membrane protein 1: a regulatory circuit.
- Epstein-Barr virus activates beta-catenin in type III latently infected B lymphocyte lines: association with deubiquitinating enzymes.
- Transforming growth factor beta/Smad3 signaling regulates IRF-7 function and transcriptional activation of the beta interferon promoter.
- Mitosis-specific hyperphosphorylation of Epstein-Barr virus nuclear antigen 2 suppresses its function.
- The Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) K1 protein induces expression of angiogenic and invasion factors.
- Effects of maribavir and selected indolocarbazoles on Epstein-Barr virus protein kinase BGLF4 and on viral lytic replication.
- Multiple signal transducers and activators of transcription are induced by EBV LMP-1.
- Tumor viruses and cell signaling pathways: deubiquitination versus ubiquitination.
- Epstein-Barr virus latent membrane protein 1 induces synthesis of hypoxia-inducible factor 1 alpha.
Fellowships
- Karolinska Institute, Research Associate, Stockholm, Sweden 1962
- Wistar Institute, Research Associate, PA, USA 1960
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