Dr. Hugh O'brodovich M.D.

Treatments

• Asthma
• Birth Defects
• Chronic Obstructive Pulmonary Disease (copd)

Publications

• PediatricsA Genome-Wide Association Study (GWAS) for Bronchopulmory Dysplasia.2013
• SEMIRS IN PERITOLOGYProgress in understanding the genetics of bronchopulmory dysplasia2013
• PLoS OneHigh Quality Genome-Wide Genotyping from Archived Dried Blood Spots without D Amplification.2013
• Pediatric ResearchRisk of bronchopulmory dysplasia by second trimester materl serum levels of alpha-fetoprotein2012
• AMERICAN JOURL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGYLung-derived soluble mediators are pathogenic in ventilator-induced lung injury2011
• Am J Physiol Lung Cell Mol PhysiolLung-derived soluble mediators are pathogenic in ventilator-induced lung injury2011
• AMERICAN JOURL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGYLong-term terbutaline exposure stimulates alpha2010
• PEDIATRIC PULMONOLOGYNHLBI Training Workshop Report2010
• JOURL OF PEDIATRICSA Scientist Track Investigator Program to Support Early Career Outcomes for Clinician Scientists2009
• AMERICAN JOURL OF RESPIRATORY CELL AND MOLECULAR BIOLOGYGlobal and Gene-Specific Translatiol Regulation in Rat Lung Development2009
• PEDIATRIC RESEARCHGlucocorticoid-Mediated Repression of REDD1 mR Expression in Rat Fetal Distal Lung Epithelial Cells2009
• PEDIATRIC RESEARCHPulmory Neuroendocrine Cell-Secreted Factors May Alter Fetal Lung Liquid Clearance2009
• EXPERIMENTAL LUNG RESEARCHPROTEASE-ACTIVATED RECEPTOR2009
• MAGNETIC RESONCE IN MEDICINEVisualizing water clearance in the lung with MRI2008
• AMERICAN JOURL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGYAmiloride-insensitive + and fluid absorption in the mammalian distal lung2008
• AMERICAN JOURL OF RESPIRATORY CELL AND MOLECULAR BIOLOGYSteroid and oxygen effects on elF4F complex, mTOR, and EC translation in fetal lung epithelia2007
• PROTEIN EXPRESSION AND PURIFICATIONPurification and characterization of a recombint rat prohaptoglobin expressed in baculovirus2007
• AMERICAN JOURL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGYEffects of cardiogenic edema fluid on ion and fluid transport in the adult lung2007
• AMERICAN JOURL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGYThe role of alpha-, beta-2007
• PEDIATRIC PULMONOLOGYAmiloride-insensitive sal potential difference varies with the menstrual cycle in cystic fibrosis2007
• PEDIATRICSPerformance of a career development and compensation program at an academic health science center2007
• AMERICAN JOURL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGYThyroid hormone and +-K+-ATPase: more than simple transcription2007
• PEDIATRICSClinical and education workload measurements using persol digital assistant-based software2006
• AMERICAN JOURL OF RESPIRATORY CELL AND MOLECULAR BIOLOGYOxygen and glucocorticoids modulate alpha EC mR translation in fetal distal lung epithelium2006
• PAEDIATRIC RESPIRATORY REVIEWSFluid clearance from the lungs of newborns, infants and children2006
• AVIATION SPACE AND ENVIRONMENTAL MEDICINEFitness to fly in an infant with congenital lobar emphysema2005
• CURRENT OPINION IN PEDIATRICSPulmory edema in infants and children2005
• JOURL OF PEDIATRICSPediatric chairs of Cada: Academic pediatric workforce2004
• AMERICAN JOURL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGYExpression of epithelial sodium channel alpha-subunit mRs with altertive 5 '2004
• AMERICAN JOURL OF RESPIRATORY CELL AND MOLECULAR BIOLOGYDifferential translatiol efficiency of EC subunits during lung development2004
• PEDIATRICSLow expression of human epithelial sodium channel2004
• JOURL OF PEDIATRICSAcquisition of competencies during the pediatric residency: A Cadian perspective2004
• PEDIATRIC PULMONOLOGYAirspace fluid clearance in the normal and edematous newborn lung2004
• PEDIATRIC PULMONOLOGYDeficient + channel expression in newborn respiratory distress syndrome2004
• PEDIATRICSEvaluation of a peer-reviewed career development2003
• JOURL OF PHYSIOLOGY-LONDONPulmory oedema fluid induces non-alpha-EC-dependent + transport2002
• AMERICAN JOURL OF RESPIRATORY AND CRITICAL CARE MEDICINEPulmory interstitial glycogenosis - A new variant of neotal interstitial lung disease2002
• AMERICAN JOURL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGYPromoter alysis of the gene encoding the beta-subunit of the rat amiloride2002
• AMERICAN JOURL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGYPulmory edema fluid movement within the lung2001
• AMERICAN JOURL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGYTranslatiol activation2001
• JOURL OF PEDIATRICSCareer development and compensation2001
• AMERICAN JOURL OF RESPIRATORY CELL AND MOLECULAR BIOLOGYFetal lung liquid secretion - Insights using the tools of inhibitors2001
• AMERICAN JOURL OF RESPIRATORY AND CRITICAL CARE MEDICINEExpression of alpha-2001
• JOURL OF HEART AND LUNG TRANSPLANTATIONTransplant immunosuppression increases2000
• PEDIATRIC RESEARCHPreventing endotoxin-stimulated alveolar macrophages from decreasing epithelium + channel2000
• AMERICAN JOURL OF RESPIRATORY AND CRITICAL CARE MEDICINEEpithelial + channel (EC) expression in the developing normal and abnormal human perital lung2000
• AMERICAN JOURL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGYOxygen induction of epithelial + transport requires heme proteins2000
• PEDIATRIC RESEARCHHormol regulation and genomic organization of the human amiloride1999
• JOURL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITIONAlterte funding arrangements to compensate physicians at Academic Health Science Centers1999
• AMERICAN JOURL OF RESPIRATORY CELL AND MOLECULAR BIOLOGYStructure and hormone responsiveness of the gene encoding the alpha-subunit of the rat amiloride1999
• GENE THERAPYMetabolic instability of plasmid D in the cytosol: a potential barrier to gene transfer1999
• JOURL OF PHYSIOLOGY-LONDONRegulation of an amiloride-sensitive +-permeable channel by a beta(2)-adrenergic agonist1999
• JOURL OF MEMBRANE BIOLOGYRoles of Ca2+ and protein tyrosine kise1999
• AMILORIDE-SENSITIVE SODIUM CHANNELSInduction of epithelial sodium channel1999
• TURE MEDICINEHSC clinical trials controversy continues1999
• ANNUAL REVIEW OF PHYSIOLOGYSodium channels in alveolar epithelial cells: Molecular characterization, biophysical properties1999
• JOURL OF BIOLOGICAL CHEMISTRYInvestigation of the anticoagulant mechanisms of a covalent antithrombin-heparin complex1998
• JOURL OF BIOLOGICAL CHEMISTRYCovalent heparin cofactor II-heparin1998
• AMERICAN JOURL OF RESPIRATORY AND CRITICAL CARE MEDICINERelation between alpha, beta1998
• AMERICAN JOURL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGYO-2-induced EC expression is associated with NF-kappa B activation1998
• AMERICAN JOURL OF RESPIRATORY CELL AND MOLECULAR BIOLOGYInfluence of mechanical stretch on thrombin regulation by fetal mixed lung cells1998
• AMERICAN JOURL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGYLiposome-mediated transfection of fetal lung epithelial cells1998
• AMERICAN JOURL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGYEffect of a novel covalent antithrombin1998
• AMERICAN JOURL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGYModulation of aquaporin 41998
• ANLS OF MEDICINESignificance of ion transport during lung development and in respiratory disease of the newborn1998
• AMERICAN JOURL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGYInhibition of amiloride-sensitive sodium1998
• AMERICAN JOURL OF PHYSIOLOGY-CELL PHYSIOLOGYFemale gender hormones regulate mR levels and function of the rat lung epithelial channel1998
• GENE THERAPYComparison between intratracheal1998
• PROCEEDINGS OF THE TIOL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMDevelopment of an epithelium1997
• JOURL OF CLINICAL INVESTIGATIONLung disease in mice with cystic fibrosis1997
• JOURL OF BIOLOGICAL CHEMISTRYCovalent antithrombin-heparin complexes with high anticoagulant activity - Intravenous1997
• PFLUGERS ARCHIV-EUROPEAN JOURL OF PHYSIOLOGYThe effect of brefeldin A on terbutaline1997
• OBRODOVICH, H. M., Mullen, B., HANM, V. L., Goodman, B. E.Active -22(+) transport by the intact lung during early posttal life1997
• Current opinion in pediatricsThe present and future role of gene therapy in the newborn.1997
• JOURL OF PEDIATRICSRespiratory distress syndrome: The importance of effective transport1997
• PROCEEDINGS OF THE ASSOCIATION OF AMERICAN PHYSICIANSImmature epithelial t channel expression is one of the pathogenetic mechanisms leading to human1996
• AMERICAN JOURL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGYIncreased Po-2 alters the bioelectric properties of fetal distal lung epithelium1996
• AMERICAN JOURL OF PHYSIOLOGY-CELL PHYSIOLOGYLUNG EPITHELIAL CHANNEL SUBUNITS ARE DIFFERENTIALLY REGULATED DURING DEVELOPMENT AND BY STEROIDS1995
• INTERTIOL JOURL OF DEVELOPMENTAL BIOLOGYLUNG FLUID RESTRICTION AFFECTS GROWTH BUT NOT AIRWAY BRANCHING OF EMBRYONIC RAT LUNG1995
• AMERICAN JOURL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGYFETAL LUNG CELL-DERIVED MATRIX ALTERS DISTAL LUNG EPITHELIAL ION-TRANSPORT1995
• New horizons (Baltimore, Md.)The role of active + transport by lung epithelium in the clearance of airspace fluid.1995
• EMBO JOURLAN SH3 BINDING REGION IN THE EPITHELIAL + CHANNEL1994
• AMERICAN JOURL OF RESPIRATORY CELL AND MOLECULAR BIOLOGYTHROMBIN INHIBITION BY FETAL DISTAL LUNG EPITHELIUM IS DIFFERENT IN FETAL AND ADULT PLASMA1994
• AMERICAN JOURL OF PHYSIOLOGYENDOTOXIN-STIMULATED ALVEOLAR MACROPHAGES IMPAIR LUNG EPITHELIAL + TRANSPORT BY AN L1994
• AMERICAN JOURL OF RESPIRATORY CELL AND MOLECULAR BIOLOGYREGIOL EXPRESSION OF CFTR IN DEVELOPING HUMAN RESPIRATORY TISSUES1994
• AMERICAN JOURL OF PHYSIOLOGYCL- REGULATION OF A CA2+1994
• CADIAN JOURL OF PHYSIOLOGY AND PHARMACOLOGYWHOLE-CELL CL- CURRENTS IN A HUMAN PERIPHERAL AIRWAY EPITHELIAL-CELL LINE1993
• CADIAN JOURL OF PHYSIOLOGY AND PHARMACOLOGYACTIVATION OF CL- CURRENTS BY INTRACELLULAR CHLORIDE IN FIBROBLASTS STABLY EXPRESSING THE HUMAN1993
• AMERICAN JOURL OF PHYSIOLOGYEXPRESSION OF THE EPITHELIAL + CHANNEL IN THE DEVELOPING RAT LUNG1993
• JOURL OF PEDIATRICSEFFICACY OF ALBUTEROL ADMINISTERED BY NEBULIZER VERSUS SPACER DEVICE IN CHILDREN WITH ACUTE ASTHMA1993
• JOURL OF APPLIED PHYSIOLOGYHINDLIMB AND LUNG LYMPH FLOWS DURING PROLONGED EXERCISE1993
• AMERICAN JOURL OF PHYSIOLOGYNOVOBIOCIN FORMS CATION-PERMEABLE ION CHANNELS IN RAT FETAL DISTAL LUNG EPITHELIUM1993
• AMERICAN JOURL OF PHYSIOLOGYONTOGENY OF ALPHA-1-ISOFORMS AND BETA-1-ISOFORMS OF +-K+-ATPASE IN FETAL DISTAL RAT LUNG EPITHELIUM1993
• AMERICAN REVIEW OF RESPIRATORY DISEASEEXOGENOUS SURFACTANT RAPIDLY INCREASES PAO2 IN MATURE RABBITS WITH LUNGS THAT CONTAIN LARGE AMOUNTS1993
• AMERICAN JOURL OF PHYSIOLOGYFETAL LUNG EPITELIAL CELLS CONTAIN 2 POPULATIONS OF AMILORIDE-SENSITIVE + CHANNELS1993
• CADIAN JOURL OF PHYSIOLOGY AND PHARMACOLOGY5-(N-ETHYL-N-ISOPROPYL)AMILORIDE SENSITIVE + CURRENTS IN INTACT FETAL DISTAL LUNG EPITHELIAL-CELLS1993
• CADIAN JOURL OF PHYSIOLOGY AND PHARMACOLOGYEFFECT OF K-CHANNEL BLOCKERS ON BASAL AND BETA1993
• AMERICAN REVIEW OF RESPIRATORY DISEASEBICARBOTE CONCENTRATION IN RHESUS-MONKEY AND GUINEA-PIG FETAL LUNG LIQUID1992
• PEDIATRIC HEMATOLOGY AND ONCOLOGYALGESIA IN CHILDREN WITH SICKLE-CELL CRISIS1992
• BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONSCYTOSOLIC CA-2+-INDUCED MODULATION OF ION SELECTIVITY AND AMILORIDE SENSITIVITY OF A CATION CHANNEL1992
• BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONSEFFECTS OF INSULIN AND TYROSINE KISE INHIBITOR ON ION1992
• AMERICAN JOURL OF PEDIATRIC HEMATOLOGY ONCOLOGYOXYGEN-THERAPY IN SICKLE-CELL DISEASE1992
• PEDIATRIC RESEARCHARGININE VASOPRESSIN AND ATRIAL-TRIURETIC1992
• HUMAN PATHOLOGYFATAL PULMORY ARTERIAL OCCLUSIVE VASCULAR-DISEASE FOLLOWING CHEMOTHERAPY IN A 9-MONTH-OLD INFANT1991
• AMERICAN JOURL OF RESPIRATORY CELL AND MOLECULAR BIOLOGYSODIUM-CHANNEL BUT NEITHER +-H+ NOR -GLUCOSE SYMPORT INHIBITORS SLOW NEOTAL LUNG WATER CLEARANCE1991
• AMERICAN JOURL OF PHYSIOLOGYINFLUENCE OF FETAL PULMORY EPITHELIUM ON THROMBIN ACTIVITY1991
• AMERICAN JOURL OF PHYSIOLOGYEPITHELIAL ION-TRANSPORT IN THE FETAL AND PERITAL LUNG1991
• BIOCHIMICA ET BIOPHYSICA ACTACATION SELECTIVE CHANNEL IN FETAL ALVEOLAR TYPE-II EPITHELIUM1991
• AMERICAN JOURL OF PEDIATRIC HEMATOLOGY ONCOLOGYCARDIOPULMORY FUNCTION DURING LONG-TERM CENTRAL VENOUS CATHETERIZATION1991
• AMERICAN JOURL OF RESPIRATORY CELL AND MOLECULAR BIOLOGYA549 LUNG EPITHELIAL-CELLS SYNTHESIZE ANTICOAGULANT MOLECULES ON THE CELL1991
• JOURL OF PEDIATRICSBRONCHOPULMORY DYSPLASIA - IMPROVEMENT IN LUNG-FUNCTION BETWEEN 7 AND 10 YEARS OF AGE1991
• BIOLOGY OF THE NEOTEINFLUENCE OF GESTATIOL-AGE ON POTENTIAL DIFFERENCE ACROSS FETAL TYPE1991
• AMERICAN REVIEW OF RESPIRATORY DISEASEWHEN THE ALVEOLUS IS FLOODING, ITS TIME TO MAN THE PUMPS1990
• AMERICAN REVIEW OF RESPIRATORY DISEASEEFFECT OF PENTOXIFYLLINE ON HEMODYMICS, ALVEOLAR FLUID REABSORPTION1990
• BIOLOGY OF THE NEOTEEFFECT OF FIBRINOGEN DEGRADATION PRODUCTS AND LUNG GROUND SUBSTANCE ON SURFACTANT FUNCTION1990
• Cadian jourl of aesthesia = Jourl cadien d'anesthésieCation channels in apical membrane of fetal alveolar epithelium.1990
• AMERICAN JOURL OF PHYSIOLOGYBIOELECTRIC PROPERTIES OF FETAL ALVEOLAR EPITHELIAL MONOLAYERS1990
• JOURL OF APPLIED PHYSIOLOGYAMILORIDE IMPAIRS LUNG WATER CLEARANCE IN NEWBORN GUINEA-PIGS1990
• JOURL OF PEDIATRICSSEQUENTIAL PULMORY-FUNCTION MEASUREMENTS DURING TREATMENT OF INFANTILE CHRONIC INTERSTITIAL1990
• JOURL OF APPLIED PHYSIOLOGYSIMULTANEOUS MEASUREMENT OF LUNG CLEARANCE RATES FOR TC-DTPA AND IN1989
• CADIAN JOURL OF PHYSIOLOGY AND PHARMACOLOGYTHE RESPONSE OF THE PULMORY CIRCULATION TO EXERCISE DURING NORMOXIA AND HYPOXIA FOLLOWING1989
• AMERICAN JOURL OF HEMATOLOGYFETAL LAMB COAGULATION SYSTEM DURING BIRTH ASPHYXIA1988
• Jourl of thoracic imagingLung clearance of 99mTc-DTPA in patients with acute lung injury and pulmory edema.1988
• AMERICAN JOURL OF HEMATOLOGYFETAL LAMB COAGULATION SYSTEM DURING NORMAL BIRTH1988
• AMERICAN JOURL OF PHYSIOLOGYANGIOTENSIN-II PREVENTS HYPOXIC PULMORY-HYPERTENSION AND VASCULAR CHANGES IN RAT1988
• THROMBOSIS AND HAEMOSTASISTHE EFFECT OF HYPOXIA ON PLATELET SURVIVAL AND SITE OF SEQUESTRATION IN THE NEWBORN RABBIT1988
• AMERICAN REVIEW OF RESPIRATORY DISEASEAIRWAY EPITHELIAL DAMAGE IN PREMATURE-INFANTS WITH RESPIRATORY-FAILURE1988
• AMERICAN REVIEW OF RESPIRATORY DISEASEPULMORY CLEARANCE OF TC-99M-DTPA IN INFANTS WHO SUBSEQUENTLY DEVELOP BRONCHOPULMORY DYSPLASIA1988
• CLINICS IN PERITOLOGYLONG-TERM OUTCOME OF PRETERM INFANTS WITH RESPIRATORY-DISEASE1987
• JOURL OF APPLIED PHYSIOLOGYOPERATION EVEREST .2. COAGULATION SYSTEM DURING PROLONGED DECOMPRESSION TO 282 TORR1987
• AMERICAN REVIEW OF RESPIRATORY DISEASEASSESSMENT OF POSTMORTEM RESPIRATORY CILIARY MOTILITY AND ULTRASTRUCTURE1987
• JOURL OF NUCLEAR MEDICINEVENTILATION SCINTIGRAPHY WITH SUBMICRONIC RADIOAEROSOL AS AN ADJUNCT1987
• JOURL OF NUCLEAR MEDICINEEXTRAPULMORY RADIOACTIVITY IN LUNG PERMEABILITY MEASUREMENTS1987
• LUNGPULMORY CLEARANCE OF TC-99M-DTPA - A NONINVASIVE ASSESSMENT OF EPITHELIAL INTEGRITY1987
• RESPIRATIONPULMORY HEMODYMICS DURING EXERCISE AFTER LOW AND HIGH-DOSES OF ACETYLSALICYLIC-ACID IN SHEEP1987
• PEDIATRIC RESEARCHPULMORY DEPOSITION SITES OF AN INHALED RADIOLABELED SUBMICRONIC AEROSOL1986
• AMERICAN REVIEW OF RESPIRATORY DISEASEEFFECT OF EXERCISE ON LUNG LYMPH-FLOW IN UNESTHETIZED SHEEP WITH INCREASED PULMORY VASCULAR1986
• SEMIRS IN NUCLEAR MEDICINEMEASUREMENT OF PULMORY EPITHELIAL PERMEABILITY WITH TC-99M-DTPA AEROSOL1986
• JOURL OF APPLIED PHYSIOLOGYINCREASES IN FACTOR-VIII COMPLEX AND FIBRINOLYTIC-ACTIVITY ARE DEPENDENT ON EXERCISE INTENSITY1986
• JOURL OF APPLIED PHYSIOLOGYEFFECT OF INSPIRATORY RESISTANCE AND PEEP ON TC-99M-DTPA CLEARANCE1986
• PEDIATRIC PULMONOLOGYAEROSOL DELIVERY TO THE RABBIT LUNG WITH AN INFANT VENTILATOR0

Dr. Hugh O'brodovich M.D.'s Practice location