Iris Z Jaffe M.D.
Cardiologist | Cardiovascular Disease
750 Washington St Tufts-Nemc Boston MA, 02111About
Iris Zamir Jaffe, MD, PhD is an Assistant Professor of Medicine at Tufts University School of Medicine and a staff member of the Division of Cardiology at Tufts Medical Center. Dr. Jaffe received her ...
Education and Training
Univ of Pa Sch of Med, Philadelphia Pa 1999
Perelman School of Medicine University of Pennsylvania 1996
Board Certification
Internal MedicineAmerican Board of Internal MedicineABIM- Cardiovascular Disease
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Functional mineralocorticoid receptors in human vascular endothelial cells regulate intercellular adhesion molecule-1 expression and promote leukocyte adhesion.
- Aldosterone regulates vascular gene transcription via oxidative stress-dependent and -independent pathways.
- Mineralocorticoid receptors in vascular function and disease.
- Distinct effects of unfractionated heparin versus bivalirudin on circulating angiogenic peptides.
- Direct regulation of blood pressure by smooth muscle cell mineralocorticoid receptors.
- Mineralocorticoid receptor antagonism inhibits vein graft remodeling in mice.
- Mineralocorticoid receptor antagonism attenuates experimental pulmonary hypertension.
- Aldosterone increases early atherosclerosis and promotes plaque inflammation through a placental growth factor-dependent mechanism.
- Smooth muscle cell mineralocorticoid receptors: role in vascular function and contribution to cardiovascular disease.
- Direct contribution of vascular mineralocorticoid receptors to blood pressure
- Mineralocorticoid receptors in vascular disease: connecting molecular pathways to
- Smooth muscle cell mineralocorticoid receptors are mandatory for aldosterone-salt to induce vascular stiffness.
- Aldosterone promotes vascular remodeling by direct effects on smooth muscle cell mineralocorticoid receptors.
- Aldosterone and vascular mineralocorticoid receptors: regulators of ion channels beyond the kidney.
- Endothelial cell mineralocorticoid receptors: turning cardiovascular risk factors into cardiovascular dysfunction.
Fellowships
- Brigham & Women's Hospital, Fellow:Cardiovascular Diseases 2001
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