Dr. Michael R Knowles MD
Pulmonologist | Pulmonary Disease
300 Meadowmont Village Circle Chapel Hill NC, 27517About
Dr. Michael Knowles practices Pulmonology in Chapel Hill, NC. A pulmonologist is a physician who possesses specialized knowledge and skill in the diagnosis and treatment of pulmonary conditions and diseases. Dr. Knowles manages patients who need life support and mechanical ventilation, and is specially trained in diseases and conditions of the chest, particularly pneumonia, asthma, tuberculosis, emphysema, and complicated chest infections.
Board Certification
Internal MedicineAmerican Board of Internal MedicineABIM- 1974
Internal MedicineAmerican Board of Internal MedicineABIM- Pulmonary Disease- 1980
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Molecular differentiation of Renibacterium salmoninarum isolates from worldwide
- Recent advances in aerosol therapy.
- Effect of aerosolized uridine-5'-triphosphate on airway clearance with cough in patients with primary ciliary dyskinesia.
- Pulmonary epithelial sodium-channel dysfunction and excess airway liquid in pseudohypoaldosteronism.
- Correction of aberrant splicing of the cystic fibrosis transmembrane conductance regulator (CFTR) gene by antisense oligonucleotides.
- Safety and biological efficacy of a lipid-CFTR complex for gene transfer in the nasal epithelium of adult patients with cystic fibrosis.
- Lung disease associated with the IVS8 5T allele of the CFTR gene.
- A modified technique for measurement of nasal transepithelial potential difference in infants.
- Germline mutations in an intermediate chain dynein cause primary ciliary dyskinesia.
- Cystic fibrosis gene mutations and pancreatitis risk: relation to epithelial ion transport and trypsin inhibitor gene mutations.
- 'CFTR-opathies': disease phenotypes associated with cystic fibrosis transmembrane regulator gene mutations.
- Mutations in DNAI1 (IC78) cause primary ciliary dyskinesia.
- What is cystic fibrosis?
- Alterations of stress related proteins in genetically altered mice revealed by two-dimensional differential in-gel electrophoresis analysis.
- Increasing concentration of inhaled saline with or without amiloride: effect on mucociliary clearance in normal subjects.
Fellowships
- UNC Chapel Hill Med School, Pulmonary, NC, USA 1980
- University of North Carolina, Chapel Hill, NC, Pulmonary Diseases 1978
Dr. Michael R Knowles MD's Practice location
Practice At 101 Manning Dr
101 Manning Dr -Chapel Hill, NC 27599Get Direction
UNC Hospitals Pulmonary Specialty Clinic
300 Meadowmont Village Circle -Chapel Hill, NC 27517Get Direction
Dr. Michael R Knowles MD's reviews
Write ReviewRecommended Articles
![]()
What Are the Medications that Can Treat Pleurisy?Pleurisy is the inflammation of the pleural membranes that line your lungs and the inside of the chest wall. It is a very painful condition that is often exacerbated by deep inspiration. Most patients with pleurisy present a sharp, stabbing-like pain over one side of the chest that aggravates while...
![]()
These Young Adults with Cystic Fibrosis Raise Awareness Through their CareersTreatment and management of Cystic Fibrosis (CF) has come a long way. It used to result in children dying at very early ages, but now they can live much longer and even flourish well into adulthood. This is a result of novel treatment methods, enhanced specialized care, dietary changes, and overall...
![]()
Sexual and Reproductive Health Care in Young Women with Cystic FibrosisThe Journal of Cystic Fibrosis has published recent study results on research into the sexual and reproductive health care in young women with cystic fibrosis.This study compared the sexual and reproductive health (SRH) care of those with CF to the general U.S. population. Both groups of women were...
![]()
Persistent and Dry Cough: What to Do?There are two types of cough: dry and productive. When you cough and mucus or phlegm is expelled, then it is a productive cough. A dry cough, on the other hand, can be caused by a random tickle, allergy, or dry air. There are natural remedies that can be used to relieve a cough. Home Remedies for...
![]()
Pulmonary Tuberculosis: A Disease That Might Spread Beyond the LungsWhat is pulmonary tuberculosis?Pulmonary tuberculosis or (TB) indicates a contagious bacterial infection involving the lungs but can also spread to various parts of the human body.What are the symptoms of pulmonary tuberculosis?People suffering from this lung condition would commonly experience the...
![]()
What Is Asthma: Get the FactsAsthma is a lung condition where the lung bronchioles constrict and get filled with mucus, narrowing the passage for air to pass through. It is a non-curable condition. However, the symptoms can be suppressed with proper medication, exercise (as prescribed by the doctor, or else, doing inappropriate...
Nearby Providers
![]()
Dr. Maria P Rivera MD300 Meadowmont Village Circle Chapel Hill NC 27517![]()
Dr. Peadar G Noone MD300 Meadowmont Village Circle Chapel Hill NC 27517![]()
Dr. Scott H Donaldson MD300 Meadowmont Village Circle Chapel Hill NC 27517![]()
Dr. Michael Bradley Drummond M.D.300 Meadowmont Village Circle Chapel Hill NC 27517![]()
Dr. Lydia Hwei Chang M.D.300 Meadowmont Village Circle Chapel Hill NC 27517![]()
Dr. Barbara Lee Levarge M.D.300 Meadowmont Village Circle Chapel Hill NC 27517
Nearest Hospitals
DUKE UNIVERSITY HOSPITALl
PO BOX 3814 DUMC ERWIN RD DURHAM NC 27710UNIVERSITY OF NORTH CAROLINA HOSPITALl
101 MANNING DRIVE CHAPEL HILL NC 27514DUKE UNIVERSITY HOSPITALl
PO BOX 3814 DUMC ERWIN RD DURHAM NC 27710UNIVERSITY OF NORTH CAROLINA HOSPITALl
101 MANNING DRIVE CHAPEL HILL NC 27514