Irwin D Bernstein
Hematologist (Pediatric) | Pediatric Hematology-Oncology
4800 Sand Point Way Ne Seattle WA, 98105About
Irwin D. Bernstein, MD, is chief of the Division of Hematology/Oncology and Bone Marrow Transplant at Seattle Childrens Hospital and professor of pediatrics at the University of Washington School of Medicine. ...
Education and Training
New York Univ Sch of Med, New York Ny 1967
New York University School of Medicine 1967
Board Certification
PediatricsAmerican Board of PediatricsABP
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Selective ablation of acute myeloid leukemia using antibody-targeted chemotherapy: a phase I study of an anti-CD33 calicheamicin immunoconjugate.
- All-trans retinoic acid delays the differentiation of primitive hematopoietic precursors (lin-c-kit+Sca-1(+)) while enhancing the terminal maturation of committed granulocyte/monocyte progenitors.
- Phase I study of (131)I-anti-CD45 antibody plus cyclophosphamide and total body irradiation for advanced acute leukemia and myelodysplastic syndrome.
- All-trans retinoic acid enhances the long-term repopulating activity of cultured hematopoietic stem cells.
- Monoclonal antibodies to the myeloid stem cells: therapeutic implications of
- Monocytes express high amounts of Notch and undergo cytokine specific apoptosis following interaction with the Notch ligand, Delta-1.
- A phase I/II trial of iodine-131-tositumomab (anti-CD20), etoposide, cyclophosphamide, and autologous stem cell transplantation for relapsed B-cell lymphomas.
- Pluripotent, cytokine-dependent, hematopoietic stem cells are immortalized by constitutive Notch1 signaling.
- Immobilization of Notch ligand, Delta-1, is required for induction of notch signaling.
- Targeting of the CD33-calicheamicin immunoconjugate Mylotarg (CMA-676) in acute
- Immunosuppressive effects of (131)I-anti-CD45 antibody in unsensitized and donor antigen-presensitized H2-matched, minor antigen-mismatched murine transplant models.
- Multidrug-resistance phenotype and clinical responses to gemtuzumab ozogamicin.
- Loss of heterozygosity in childhood de novo acute myelogenous leukemia.
- The Notch ligand, Delta-1, inhibits the differentiation of monocytes into macrophages but permits their differentiation into dendritic cells.
- All-trans retinoic acid facilitates oncoretrovirus-mediated transduction of hematopoietic repopulating stem cells.
Irwin D Bernstein's Practice location
Practice At 4800 Sand Point Way Ne
4800 Sand Point Way Ne -Seattle, WA 98105Get Direction
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Douglas S Hawkins Other4800 Sand Point Way Ne Seattle WA 98105
Nearest Hospitals
SWEDISH MEDICAL CENTER / CHERRY HILLl
500 17TH AVENUE SEATTLE WA 98122GROUP HEALTH CENTRAL HOSPITALl
201 - 16TH AVENUE EAST SEATTLE WA 98112SEATTLE CHILDREN'S HOSPITALl
4800 SAND POINT WAY NE, PO BOX C-5371 SEATTLE WA 98105