Dr. Christopher T Denny M.D.
Hematologist (Pediatric) | Pediatric Hematology-Oncology
10833 Le Conte Ave 12-441 Mdcc Los Angeles CA, 90095About
Dr. Christopher Denny is a pediatric hematologist practicing in Los Angeles, CA. Dr. Denny specializes in treating children that have a blood disease or cancer. Such blood diseases include disorders of red blood cells, white blood cells and/or platelets. The types of cancers that Dr. Denny treats include leukemias, lymphomas and certain tumors. Dr. Denny can also treat bleeding disorders in children. Pediatric hematologists can be found in childrens hospitals, community hospitals, university medical centers and more.
Education and Training
Univ of Pa Sch of Med, Philadelphia Pa 1980
Board Certification
Emergency MedicineAmerican Board of Emergency MedicineABEM
DermatologyAmerican Board of DermatologyABD- 1990
PediatricsAmerican Board of PediatricsABP- 1986
Provider Details
Expert Publications
Data provided by the National Library of Medicine- TCL1 oncogene expression in AIDS-related lymphomas and lymphoid tissues.
- Divergent Ewing's sarcoma EWS/ETS fusions confer a common tumorigenic phenotype on NIH3T3 cells.
- EWS/ETS fusion genes induce epithelial and neuroectodermal differentiation in NIH 3T3 fibroblasts.
- Cross-contamination limits the use of recycled anion exchange resins for preparing plasmid DNA.
- EWS-FLI1, EWS-ERG, and EWS-ETV1 oncoproteins of Ewing tumor family all suppress transcription of transforming growth factor beta type II receptor gene.
- The COOH-terminal domain of FLI-1 is necessary for full tumorigenesis and transcriptional modulation by EWS/FLI-1.
- DNA binding domain-independent pathways are involved in EWS/FLI1-mediated oncogenesis.
- Biology of EWS/ETS fusions in Ewing's family tumors.
- Loss of p16 pathways stabilizes EWS/FLI1 expression and complements EWS/FLI1 mediated transformation.
- Focus on embryonal malignancies.
- PIM3 proto-oncogene kinase is a common transcriptional target of divergent EWS/ETS oncoproteins.
- Functional analysis of the EWS/ETS target gene uridine phosphorylase.
- Creation of a yeast artificial chromosome fragmentation vector based on lysine-2.
- Cooperative DNA binding with AP-1 proteins is required for transformation by EWS-Ets fusion proteins.
- Multiple aromatic side chains within a disordered structure are critical for transcription and transforming activity of EWS family oncoproteins.
Awards
- 2010-2012 Southern California Super Doctors
- 2009 Southern California Super Doctors 2008
- 2007 Los Angeles Super Doctors
Treatments
- Cancer
Fellowships
- Pediatrics/Hematology-Oncology, National Institutes of Health, The Clinical Center 1983
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