Dr. James D. Brooks M.D.

Awards

• Stanford University 2012 Keith and Jan Hurlbut Professor 
•  2004-2013 Best Doctors Inc. 
•  2010 Listing in Guide to America's Top Surgeons, Consumers' Research Counc 
• Stanford University School of Medicine 2002-2003 Leutje-Stubbs Faculty Scholar 
• Kidney Cancer Association 2000-2002 Eugene P. Schonfeld Medical Research Award 
• Doris Duke Foundation 1998-2002 Clinician Scientist Award 
•  1995-1997 Dornier Research Scholar, American Foundation for Urologic Disease 

Treatments

• Prostate Cancer

Fellowships

• Johns Hopkins University MD    1997
• Johns Hopkins University,Baltimore, Md, Usa   1997

Publications

• Pathologytionwide prevalence of lymph node metastases in Gleason score 3?+?3?=?6 prostate cancer.2014
• jourl of urologyProstate cancer risk profiles of asian-american men2014
• UrologyUtilization of rel mass biopsy in patients with rel cell carcinoma.2014
• jourl of urologyEpigenetic changes in histologically normal prostate tissues.2013
• jourl of urologyComprehensive gene expression changes associated with mouse posttal kidney development.2013
• CLINICAL CANCER RESEARCHUriry TMPRSS2:ERG and PCA3 in an Active Surveillance Cohort2013
• The Open Prostate Cancer JourlTreatment and mortality in men with localized prostate cancer2013
• Applied immunohistochemistry & molecular morphology : AIMM / official Identification and Characterization of 2 Testicular Germ Cell Markers, Glut3 and Cycli2.0
• ADVANCES IN ATOMIC PATHOLOGYA Model for the Design2013
• CancerMaging localized prostate cancer in the era of prostate-specific antigen screening.0
• Intertiol jourl of cancer. Jourl intertiol du cancerUtilization of cytoreductive nephrectomy and patient survival in the targeted therapy era.0
• BJU intertiolHigher rates of upgrading and upstaging0
• Genome biologyDifferential D methylation with age displays both common2013
• PLOS ONEmR-Seq of Single Prostate Cancer Circulating Tumor Cells Reveals Recapitulation of Gene Expression2012
• APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGYEvaluation of Putative Rel Cell Carcinoma Markers PAX-2, PAX-82012
• JOURL OF UROLOGYGene Expression Changes Induced by Unilateral Ureteral Obstruction in Mice2012
• JOURL OF MAGNETIC RESONCE IMAGINGMethods for registration of magnetic resonce images of ex vivo prostate specimens with histology2012
• BRITISH JOURL OF CANCEREven-skipped homeobox 1 is frequently hypermethylated in prostate cancer2012
• GENOME RESEARCHTranslatiol genomics: The challenge of developing cancer biomarkers2012
• Translatiol Andrology and UrologyPIVOT and the challenges of localized prostate cancer care0
• JOURL OF UROLOGYThe Potential Impact of Reproducibility of Gleason Grading2011
• GENOME RESEARCHD methylation profiling reveals novel biomarkers2011
• TUREIntegrated genomic alyses of ovarian carcinoma2011
• JOURL OF UROLOGYSmall Prostate Size and High Grade Disease-Biology or Artifact?2011
• UROLOGIC ONCOLOGY-SEMIRS AND ORIGIL INVESTIGATIONSComparison of prostate cancer tumor volume2011
• MODERN PATHOLOGYSpecificity of brachyury in the distinction of chordoma from clear cell rel cell carcinoma2011
• Intertiol jourl of urology : official jourl of the Japanese UrologicalLength of site-specific positive surgical margins as a risk factor for biochemical recurrence0
• HUMAN PATHOLOGYThe distribution of PAX-2 immunoreactivity in the prostate gland, semil vesicle2010
• UROLOGYCary Prostate Active Surveillance Study2010
• Genes & cancerMolecular Stratification of Clear Cell Rel Cell Carcinoma by Consensus Clustering2010
• The Open Prostate Cancer JourlGene expression changes induced by genistein in the prostate cancer cell line LNCaP2010
• The Open Prostate Cancer JourlAdjuvant docetaxel and abbreviated androgen deprivation therapy2010
• UROLOGIC ONCOLOGY-SEMIRS AND ORIGIL INVESTIGATIONSPrognostic significance of prostate cancer origiting from the transition zone2009
• BMC GENOMICSDisorders of sex development expose transcriptiol autonomy of genetic sex and androgen2009
• PLOS ONEAlteration of Gene Expression Sigtures of Cortical Differentiation2009
• JOURL OF MOLECULAR MEDICINE-JMMApolipoprotein D (APOD) is a putative biomarker of androgen receptor function in androgen2009
• AMERICAN JOURL OF CLINICAL PATHOLOGYRecommendations for the Reporting of Surgically Resected Specimens of Rel Cell Carcinoma2009
• INTERTIOL JOURL OF CANCERInhibition of prostaglandin synthesis and actions by genistein2009
• HUMAN PATHOLOGYRecommendations for the reporting of surgically resected specimens of rel cell carcinoma The2009
• INTERTIOL JOURL OF RADIATION ONCOLOGY BIOLOGY PHYSICSSTEREOTACTIC BODY RADIOTHERAPY FOR LOCALIZED PROSTATE CANCER2009
• BMC clinical pathologyCD 9 and vimentin distinguish clear cell from chromophobe rel cell carcinoma.2009
• TUREComprehensive genomic characterization defines human glioblastoma genes and core pathways2008
• PROSTATEIdentification of candidate prostate cancer genes through comparative expression-profiling of semil2008
• INTERTIOL JOURL OF RADIATION ONCOLOGY BIOLOGY PHYSICSPostoperative prostate2008
• AMERICAN JOURL OF SURGICAL PATHOLOGYhCAP-D3 expression marks a prostate cancer subtype with favorable clinical behavior and androgen2008
• The Open Prostate Cancer JourlThe impact of tumor volume on outcomes after radical prostatectomy2008
• CANCER RESEARCHGenomic profiling reveals altertive genetic pathways of prostate tumorigenesis2007
• AMERICAN JOURL OF SURGICAL PATHOLOGYPlacental S100 (S100P) and GATA32007
• CANCER LETTERSEndothelin-1 promotes cell survival in rel cell carcinoma through the ETA receptor2007
• JOURL OF UROLOGYSelenomethionine induced transcriptiol programs in human prostate cancer cells2007
• JOURL OF CELLULAR PHYSIOLOGYDistinctive gene expression of prostatic stromal cells cultured from diseased versus normal tissues2007
• JOURL OF MOLECULAR MEDICINE-JMMCell-line and tissue-specific sigtures of androgen receptor-coregulator transcription2006
• OMICS-A JOURL OF INTEGRATIVE BIOLOGYApplication of genomic technologies to human prostate cancer2006
• PLOS MEDICINEGene expression profiling predicts survival in conventiol rel cell carcinoma2006
• JOURL OF CLINICAL ONCOLOGYPreoperative PSA velocity is an independent prognostic factor2005
• PROSTATEGenome-wide characterization of gene expression variations2005
• JOURL OF PEDIATRIC SURGERYJuvenile posttraumatic high-flow priapism: current magement dilemmas2005
• PLOS BIOLOGYA transcriptiol profile of aging in the human kidney2004
• JOURL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGYMolecular activity of 12004
• INTERTIOL JOURL OF RADIATION ONCOLOGY BIOLOGY PHYSICSRadiotherapy after radical prostatectomy: Does transient androgen suppression improve outcomes?2004
• JOURL OF UROLOGYLower body mass index is associated with a higher prostate cancer detection rate2004
• PROSTATEAlysis of vitamin D-regulated gene expression in LNCaP human prostate cancer cells using cD2004
• UROLOGIC ONCOLOGY-SEMIRS AND ORIGIL INVESTIGATIONSTime trends in pathologic features of radical prostatectomy - impact of family history2004
• MOLECULAR BIOLOGY OF THE CELLGene expression in the normal adult human kidney assessed by complementary D microarray2004
• MOLECULAR BIOLOGY OF THE CELLDiverse effects of methylseleninic acid on the transcriptiol program of human prostate cancer cells2004
• PROCEEDINGS OF THE TIOL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMGene expression profiling identifies clinically relevant subtypes of prostate cancer2004
• PROCEEDINGS OF THE TIOL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMGene expression patterns in human embryonic stem cells and human pluripotent germ cell tumors2003
• AMERICAN JOURL OF PATHOLOGYGene expression patterns in rel cell carcinoma assessed by complementary D microarray2003
• AMERICAN JOURL OF SURGICAL PATHOLOGYExpression of FKBP12 in benign2003
• Current opinion in urologyMicroarray alysis in prostate cancer research.2002
• JOURL OF BIOLOGICAL CHEMISTRYNovel pathways associated with bypassing cellular senescence in human prostate epithelial cells2002
• EUROPEAN UROLOGYAtomy of the rectourethralis muscle2002
• GENOME BIOLOGYTranscriptiol programs activated by exposure of human prostate cancer cells to androgen0
• PathologyNationwide prevalence of lymph node metastases in Gleason score 3?+?3?=?6 prostate cancer.2014
• journal of urologyProstate cancer risk profiles of asian-american men2014
• UrologyReply.2014
• UrologyUtilization of renal mass biopsy in patients with renal cell carcinoma.2014
• The ProstateIncreased expression of GCNT1 is associated with altered O-glycosylation of PSA, PAP0
• Applied immunohistochemistry & molecular morphologyEvaluation of SF-1 Expression in Testicular Germ Cell Tumors2013
• journal of urologyEpigenetic changes in histologically normal prostate tissues.2013
• journal of urologyComprehensive gene expression changes associated with mouse postnatal kidney development.2013
• CLINICAL CANCER RESEARCHUrinary TMPRSS2:ERG and PCA3 in an Active Surveillance Cohort2013
• ONCOGENEIncreased expression of NuSAP in recurrent prostate cancer is mediated by E2F12013
• The Open Prostate Cancer JournalTreatment and mortality in men with localized prostate cancer2013
• Applied immunohistochemistry & molecular morphology : AIMM / official Identification and Characterization of 2 Testicular Germ Cell Markers, Glut3 and CyclinA2.0
• ADVANCES IN ANATOMIC PATHOLOGYA Model for the Design2013
• CancerManaging localized prostate cancer in the era of prostate-specific antigen screening.0
• International journal of cancer. Journal international du cancerUtilization of cytoreductive nephrectomy and patient survival in the targeted therapy era.0
• BJU internationalHigher rates of upgrading and upstaging0
• Genome biologyDifferential DNA methylation with age displays both common2013
• PLOS ONEmRNA-Seq of Single Prostate Cancer Circulating Tumor Cells Reveals Recapitulation of Gene2012
• APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGYEvaluation of Putative Renal Cell Carcinoma Markers PAX-2, PAX-82012
• JOURNAL OF UROLOGYGene Expression Changes Induced by Unilateral Ureteral Obstruction in Mice2012
• ONCOGENERecurrent deletion of CHD1 in prostate cancer with relevance to cell invasiveness2012
• JOURNAL OF MAGNETIC RESONANCE IMAGINGMethods for registration of magnetic resonance images of ex vivo prostate specimens with histology2012
• BRITISH JOURNAL OF CANCEREven-skipped homeobox 1 is frequently hypermethylated in prostate cancer2012
• UROLOGYPerformance Characteristics of Prostate2012
• CANCER RESEARCHDeficiency in Mammalian Histone H2B Ubiquitin Ligase Bre1 (Rnf202012
• King, C. R., Brooks, J. D., Gill, H., Presti, J. C.LONG-TERM OUTCOMES FROM A PROSPECTIVE TRIAL OF STEREOTACTIC BODY RADIOTHERAPY FOR LOW2012
• GENOME RESEARCHTranslational genomics: The challenge of developing cancer biomarkers2012
• Translational Andrology and UrologyPIVOT and the challenges of localized prostate cancer care0
• JOURNAL OF UROLOGYThe Potential Impact of Reproducibility of Gleason Grading2011
• GENOME RESEARCHDNA methylation profiling reveals novel biomarkers2011
• NATUREIntegrated genomic analyses of ovarian carcinoma2011
• JOURNAL OF UROLOGYSmall Prostate Size and High Grade Disease-Biology or Artifact?2011
• PLOS ONEA Tri-Marker Proliferation Index Predicts Biochemical Recurrence after Surgery for Prostate Cancer2011
• UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONSComparison of prostate cancer tumor volume2011
• MODERN PATHOLOGYSpecificity of brachyury in the distinction of chordoma from clear cell renal cell carcinoma2011
• International journal of urology : official journal of the Japanese UrLength of site-specific positive surgical margins as a risk factor for biochemical recurrence0
• Urologic oncologySmoking and adverse outcomes at radical prostatectomy.0
• HUMAN PATHOLOGYThe distribution of PAX-2 immunoreactivity in the prostate gland, seminal vesicle2010
• UROLOGYCanary Prostate Active Surveillance Study2010
• Genes & cancerMolecular Stratification of Clear Cell Renal Cell Carcinoma by Consensus Clustering Reveals2010
• The Open Prostate Cancer JournalGene expression changes induced by genistein in the prostate cancer cell line LNCaP2010
• The Open Prostate Cancer JournalAdjuvant docetaxel and abbreviated androgen deprivation therapy2010
• UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONSPrognostic significance of prostate cancer originating from the transition zone2009
• BMC GENOMICSDisorders of sex development expose transcriptional autonomy of genetic sex and androgen2009
• PLOS ONEAlteration of Gene Expression Signatures of Cortical Differentiation2009
• JOURNAL OF MOLECULAR MEDICINE-JMMApolipoprotein D (APOD) is a putative biomarker of androgen receptor function in androgen2009
• PROSTATEProstatic Soy Isoflavone Concentrations Exceed Serum Levels After Dietary Supplementation2009
• AMERICAN JOURNAL OF CLINICAL PATHOLOGYRecommendations for the Reporting of Surgically Resected Specimens of Renal Cell Carcinoma2009
• INTERNATIONAL JOURNAL OF CANCERInhibition of prostaglandin synthesis and actions by genistein2009
• HUMAN PATHOLOGYRecommendations for the reporting of surgically resected specimens of renal cell carcinoma The2009
• INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICSSTEREOTACTIC BODY RADIOTHERAPY FOR LOCALIZED PROSTATE CANCER2009
• PROSTATETemporal Changes in Gene Expression Induced by Sulforaphane in Human Prostate Cancer Cells2009
• BMC clinical pathologyCD 9 and vimentin distinguish clear cell from chromophobe renal cell carcinoma.2009
• NATUREComprehensive genomic characterization defines human glioblastoma genes and core pathways2008
• PROSTATEIdentification of candidate prostate cancer genes through comparative expression2008
• INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICSPostoperative prostate2008
• AMERICAN JOURNAL OF SURGICAL PATHOLOGYhCAP-D3 expression marks a prostate cancer subtype with favorable clinical behavior and androgen2008
• The Open Prostate Cancer JournalThe impact of tumor volume on outcomes after radical prostatectomy2008
• BMC GENOMICSIntrinsic androgen-dependent gene expression patterns revealed by comparison of genital fibroblasts2007
• CANCER RESEARCHGenomic profiling reveals alternative genetic pathways of prostate tumorigenesis2007
• AMERICAN JOURNAL OF SURGICAL PATHOLOGYPlacental S100 (S100P) and GATA32007
• NUCLEIC ACIDS RESEARCHA promoting role of androgen receptor in androgen-sensitive and -insensitive prostate cancer cells2007
• MODERN PATHOLOGYA variant TMPRSS2 isoform2007
• CANCER LETTERSEndothelin-1 promotes cell survival in renal cell carcinoma through the ETA receptor2007
• JOURNAL OF UROLOGYSelenomethionine induced transcriptional programs in human prostate cancer cells2007
• JOURNAL OF CELLULAR PHYSIOLOGYDistinctive gene expression of prostatic stromal cells cultured from diseased versus normal tissues2007
• JOURNAL OF MOLECULAR MEDICINE-JMMCell-line and tissue-specific signatures of androgen receptor-coregulator transcription2006
• OMICS-A JOURNAL OF INTEGRATIVE BIOLOGYApplication of genomic technologies to human prostate cancer2006
• UROLOGYReliability of small amounts of cancer in prostate biopsies to reveal pathologic grade2006
• UROLOGYRefractory hematuria from amyloidosis successfully treated by splenectomy2006
• BMC CANCERModest induction of phase 2 enzyme activity in the F-344 rat prostate2006
• PLOS MEDICINEGene expression profiling predicts survival in conventional renal cell carcinoma2006
• CANCER RESEARCHThe retinoic acid synthesis gene ALDH1a2 is a candidate tumor suppressor in prostate cancer2005
• JOURNAL OF CLINICAL ONCOLOGYPreoperative PSA velocity is an independent prognostic factor2005
• PROSTATEGenome-wide characterization of gene expression variations2005
• JOURNAL OF PEDIATRIC SURGERYJuvenile posttraumatic high-flow priapism: current management dilemmas2005
• CLINICAL CANCER RESEARCHReg IV: A promising marker of hormone refractory metastatic prostate cancer2005
• CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTIONResveratrol-induced gene expression profiles in human prostate cancer cells2005
• PROSTATEMolecular targets of Doxazosin in human prostatic stromal cells2005
• UROLOGYPositive family history of prostate cancer not2005
• Cancer genomics & proteomicsMicroarray Data Mining for Potential Selenium Targets in Chemoprevention of Prostate Cancer.2005
• PLOS BIOLOGYA transcriptional profile of aging in the human kidney2004
• UROLOGYVascular invasion predicts recurrence after radical prostatectomy2004
• JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGYMolecular activity of 12004
• INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICSRadiotherapy after radical prostatectomy: Does transient androgen suppression improve outcomes?2004
• JOURNAL OF UROLOGYLower body mass index is associated with a higher prostate cancer detection rate2004
• PROSTATEAnalysis of vitamin D2004
• UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONSTime trends in pathologic features of radical prostatectomy - impact of family history2004
• UROLOGYBiochemical remission after resection of prostate cancer lung metastasis2004
• MOLECULAR BIOLOGY OF THE CELLGene expression in the normal adult human kidney assessed by complementary DNA microarray2004
• MOLECULAR BIOLOGY OF THE CELLDiverse effects of methylseleninic acid on the transcriptional program of human prostate cancer2004
• PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OGene expression profiling identifies clinically relevant subtypes of prostate cancer2004
• PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OGene expression patterns in human embryonic stem cells and human pluripotent germ cell tumors2003
• AMERICAN JOURNAL OF PATHOLOGYGene expression patterns in renal cell carcinoma assessed by complementary DNA microarray2003
• UROLOGYBiochemical recurrence without PSA progression characterizes a subset of patients after radical2003
• GENOME BIOLOGYDifferential gene-expression patterns in genital fibroblasts of normal males and 462003
• AMERICAN JOURNAL OF SURGICAL PATHOLOGYExpression of FKBP12 in benign2003
• CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTIONIdentification of potential prostate cancer preventive agents through induction of quinone reduct2002
• PROSTATEPolymorphisms in the androgen receptor and type II 5 alpha2002
• Current opinion in urologyMicroarray analysis in prostate cancer research.2002
• PROSTATESilencing of pi-class glutathione S-transferase in MDA PCa 2a and MDA PCa 2b cells2002
• JOURNAL OF BIOLOGICAL CHEMISTRYNovel pathways associated with bypassing cellular senescence in human prostate epithelial cells2002
• EUROPEAN UROLOGYAnatomy of the rectourethralis muscle2002
• GENOME BIOLOGYTranscriptional programs activated by exposure of human prostate cancer cells to androgen0

Experience & Accolades

• MemberMembership Committee
• Member2004 - 2008 Society for Basic Urologic Research
• Vice Chair 2014 - 2014 Department of Urology
• Member2013 - 2014 Associate Dean, Academic Affairs, Stanford University School of Medicine
• Member2012 - 2014 Chief, Urologic Oncology, Department of Urology
• Associate Chair 2010 - 2014 Prostate Cancer Working Group EDRN
• Member2008 - 2014 Editor-in-Chief, The Open Prostate Cancer Journal
• Member2011 - 2014 Editorial Board, Andrology
• Member2010 - 2014 Editorial Board, Prostate Cancer
• Member2000 - 2014 Editorial Board, The Prostate
• Acting Chair2012 - 2012 Department of Urology

Dr. James D. Brooks M.D.'s Practice location