Dr. Randall J Kimple M.D. PH.D.
Radiation Oncologist | Radiation Oncology
1111 Highland Ave Wimr 3148 Madison WI, 53705About
Dr. Randall Kimple practices Radiation Oncology in Madison, WI. Radiation oncology is a medical specialty that involves treating cancer with radiation. Dr. Kimple specializes in treating cancer with radiation, using radiation therapy to treat a wide variety of cancers. Radiation therapy uses carefully targeted and regulated doses of high-energy radiation to kill cancer cells.
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Expert Publications
Data provided by the National Library of Medicine- RGS12 and RGS14 GoLoco motifs are G alpha(i) interaction sites with guanine nucleotide dissociation inhibitor Activity.
- Structural determinants for GoLoco-induced inhibition of nucleotide release by Galpha subunits.
- Translation of polarity cues into asymmetric spindle positioning in Caenorhabditis elegans embryos.
- Established and emerging fluorescence-based assays for G-protein function: heterotrimeric G-protein alpha subunits and regulator of G-protein signaling (RGS) proteins.
- Established and emerging fluorescence-based assays for G-protein function: Ras-superfamily GTPases.
- Guanine nucleotide dissociation inhibitor activity of the triple GoLoco motif protein G18: alanine-to-aspartate mutation restores function to an inactive second GoLoco motif.
- The GoLoco motif: heralding a new tango between G protein signaling and cell division.
- Return of the GDI: the GoLoco motif in cell division.
- Purification and in vitro functional analyses of RGS12 and RGS14 GoLoco motif peptides.
- RGS14 is a mitotic spindle protein essential from the first division of the mammalian zygote.
- G-protein signaling: back to the future.
- D2 dopamine receptor activation of potassium channels is selectively decoupled by Galpha-specific GoLoco motif peptides.
- G alpha selectivity and inhibitor function of the multiple GoLoco motif protein GPSM2/LGN.
- Structure-based protocol for identifying mutations that enhance protein-protein binding affinities.
- Regulator of G-protein signaling 14 (RGS14) is a selective H-Ras effector.
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