Dr. Frank Milton Balis M.D.
Hematologist (Pediatric) | Pediatric Hematology-Oncology
3401 Civic Center Blvd Children's Hospital Philadelphia PA, 19104About
As director of Clinical Cancer Research for the Division of Oncology and interim chief of the Division of Oncology at The Children's Hospital of Philadelphia, I facilitate the clinical research of man ...
Education and Training
Vanderbilt Univ Sch of Med, Nashville Tn 1975
Vanderbilt University School of Medicine 1975
Board Certification
PediatricsAmerican Board of PediatricsABP- Pediatric Hematology-Oncology
DermatologyAmerican Board of DermatologyABD
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Intraventricular concentration times time (C x T) methotrexate and cytarabine for patients with recurrent meningeal leukemia and lymphoma.
- Pharmacokinetics of oral zidovudine entrapped in biodegradable nanospheres in rabbits.
- 2'-beta-fluoro-2',3'-dideoxyadenosine, lodenosine, in rhesus monkeys: plasma and cerebrospinal fluid pharmacokinetics and urinary disposition.
- Effect of P-glycoprotein modulation with cyclosporin A on cerebrospinal fluid penetration of doxorubicin in non-human primates.
- Methotrexate distribution within the subarachnoid space after intraventricular and intravenous administration.
- Proton magnetic resonance spectroscopic imaging in children with recurrent primary brain tumors.
- Effect of fluconazole on the pharmacokinetics of doxorubicin in nonhuman
- Real-time fluorescence assay for O6-alkylguanine-DNA alkyltransferase.
- Clinical trials in childhood cancers.
- Plasma and cerebrospinal fluid pharmacokinetics of O6-benzylguanine and analogues in nonhuman primates.
- Probe calibration in transient microdialysis in vivo.
- Comparison of one-, two-, and three-dimensional measurements of childhood brain tumors.
- Effect of probenecid on ventricular cerebrospinal fluid methotrexate pharmacokinetics after intralumbar administration in nonhuman primates.
- A phase I trial and pharmacokinetic study of 9-cis-retinoic acid (ALRT1057) in pediatric patients with refractory cancer: a joint Pediatric Oncology Branch, National Cancer Institute, and Children's Cancer Group study.
- Synthesis and fluorescence characterization of pteridine adenosine nucleoside analogs for DNA incorporation.
Awards
- 2008 NIH Award of Merit for successful clinical development of glucarpidase
- 2003 NIH Award of Merit for outstanding contributions as Clinical Director
- 2001 NCI Mentor of Merit Award
- 2000 Public Health Service Outstanding Service Medal
- 1998 Division of Clinical Sciences Director's Award
- 1990 Public Health Service Unit Commendation
- 1988 Society for Pediatric Research
- 1978 Amos Christie Award in Pediatrics
- 1974 Alpha Omega Alpha
- 1970 Phi Beta Kappa
Treatments
- Bone Cancer
- Leukemia
- Dermal Aesthetics
- Extra Corporeal Shockwave Therapy
Professional Memberships
- Member Children's Oncology Group
- Member American Society of Clinical Oncology
- Member American Association for Cancer Research
- Member Society for Translational Oncology
- Member Society for Pediatric Research
- Member Developmental Therapeutics Committee
Fellowships
- Pediatric Oncology Research - The Children's Orthopedic Hospital and Medical Center, Seattle, WA
Experience & Accolades
- Member2010 - 2014eIRB Smartform version 2 Advisory Committee
- Member2009 - 2014 CCCR Clinical Research Quality Assurance Committee
- Member2009 - 2014 CCCR Pediatric Protocol Review Committee
- Member2009 - 2014 Pediatric Subcommittee of the Oncological Drugs Advisory Committee, FDA
- Member2009 - 2014 CCCR Cancer Leadership Group
- Member2009 - 2014 University of Pennsylvania Cancer Center Strategy Group
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