Virginia C Broudy
Hematologist-Pathologist | Hematology
Harborview Medical Center 325 9th Ave Seattle WA, 98104About
Dr. Virginia Broudy is a hematology pathologist practicing in Seattle, WA. Dr. Broudy specializes in reviewing blood samples and interpreting laboratory results. These results give them an idea of whether certain diseases are malignant or not, in order for them to properly determine what exact treatment is needed. Hematology pathologists are normally experts in leukemia, lymphoma, anemia, hemophilia and many other blood diseases.
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Expert Publications
Data provided by the National Library of Medicine- Deletion of the extracellular membrane-distal cytokine receptor homology module of Mpl results in constitutive cell growth and loss of thrombopoietin binding.
- Successful nonmyeloablative allogeneic hematopoietic stem cell transplant in an acute leukemia patient with chemotherapy-induced marrow aplasia and progressive pulmonary aspergillosis.
- Tyrosine 462 of the membrane-proximal F'-G' loop of murine Mpl is not essential for high-affinity binding of thrombopoietin.
- Do the preclinical effects of thrombopoietin correlate with its in vitro properties?
- Basis of hematopoietic defects in platelet-derived growth factor (PDGF)-B and PDGF beta-receptor null mice.
- Soluble Kit receptor blocks stem cell factor bioactivity in vitro.
- Identification and characterization of an isoform of murine Mpl.
- Familial and congenital polycythemia in three unrelated families.
- Absence of abnormalities of c-kit or its ligand in two patients with Diamond-Blackfan anemia.
- Further phenotypic characterization and isolation of human hematopoietic progenitor cells using a monoclonal antibody to the c-kit receptor.
- Nonhematopoietic tumor cell lines express stem cell factor and display c-kit receptors.
- AMG531 stimulates megakaryopoiesis in vitro by binding to Mpl.
- Characterization of the structure of the erythropoietin receptor by ligand blotting.
- Erythropoietin receptor characteristics on primary human erythroid cells.
- Muramyl dipeptide induces production of hemopoietic growth factors in vivo by a mechanism independent of tumor necrosis factor.
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