David Anthony Dichek
Cardiologist | Cardiovascular Disease
University Of Washington Medical Ctr 1959 Ne Pacific St Seattle WA, 98195About
Dr. Dichek is a UW professor of medicine in the Division of Cardiology and the division's associate director of research. He holds the John L. Locke Jr. Family Endowed Chair in Cardiovascular Research ...
Education and Training
Univ of Ca, Los Angeles, Ucla Sch of Med, Los Angeles Ca 1984
University of California 1984
Board Certification
Internal MedicineAmerican Board of Internal MedicineABIM- Cardiovascular Disease
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Adventitial delivery minimizes the proinflammatory effects of adenoviral vectors.
- Seeding of intracoronary stents with endothelial cells: current status and future prospects.
- Optimizing vascular gene transfer of plasminogen activator inhibitor 1.
- Retroviral vector-mediated expression of hirudin by human vascular endothelial cells: implications for the design of retroviral vectors expressing biologically active proteins.
- A mouse model of arterial gene transfer: antigen-specific immunity is a minor determinant of the early loss of adenovirus-mediated transgene expression.
- Expression of Fas ligand in arteries of hypercholesterolemic rabbits accelerates atherosclerotic lesion formation.
- Cardiovascular overexpression of transforming growth factor-beta(1) causes abnormal yolk sac vasculogenesis and early embryonic death.
- Second-generation adenoviral vectors do not prevent rapid loss of transgene expression and vector DNA from the arterial wall.
- Receptor-mediated regulation of plasminogen activator function: plasminogen activation by two directly membrane-anchored forms of urokinase.
- Germline incorporation of a replication-defective adenoviral vector in mice does not alter immune responses to adenoviral vectors.
- Plasminogen activator inhibitor type 1 increases neointima formation in balloon-injured rat carotid arteries.
- Inclusion of the E3 region in an adenoviral vector decreases inflammation and neointima formation after arterial gene transfer.
- Increased expression of urokinase during atherosclerotic lesion development causes arterial constriction and lumen loss, and accelerates lesion growth.
- Optimization of retroviral vector-mediated gene transfer into endothelial cells in vitro.
- Macrophage-targeted overexpression of urokinase causes accelerated atherosclerosis, coronary artery occlusions, and premature death.
Treatments
- Heart Disease
- Coronary Artery Disease (cad)
- Pain
Fellowships
- Johns Hopkins University SOM
- Massachusetts General Hospital
- National Institutes of Health
David Anthony Dichek's Practice location
Practice At University Of Washington Medical Ctr 1959 Ne Pacific St
University Of Washington Medical Ctr 1959 Ne Pacific St -Seattle, WA 98195Get Direction
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Nearby Providers
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Jason A. Talavera M.D.12728 19TH AVE SE EVERETT WA 98208![]()
Jason Trust1959 NE Pacific St Seattle WA 98195![]()
Timothy Dewhurst M.D.125 16TH AVE E SEATTLE WA 98112![]()
Michael G. Hegewald M.D.2011 Nw Myhre Pl Silverdale WA 98383![]()
Stephanie G Cooper MD325 9th Ave Seattle WA 98104![]()
William J Stanley MD21616 76th Ave W Edmonds WA 98026
Nearest Hospitals
SWEDISH MEDICAL CENTERl
747 BROADWAY SEATTLE WA 98122GROUP HEALTH CENTRAL HOSPITALl
201 - 16TH AVENUE EAST SEATTLE WA 98112SEATTLE CHILDREN'S HOSPITALl
4800 SAND POINT WAY NE, PO BOX C-5371 SEATTLE WA 98105