Dr. Arthur Edward Frankel MD
Hematologist-Oncologist | Hematology & Oncology
328 W Main Lewisville TX, 75057About
Dr. Arthur Frankel is a hematologist oncologist practicing in Lewisville, TX. Dr. Frankel specializes in the diagnosis, treatment and prevention of blood diseases such as anemia, hemophilia, sickle-cell disease, leukemia and lymphoma. Hematologist Oncologists are also trained in the study of cancer and its attack on other organs.
Board Certification
Internal MedicineAmerican Board of Internal MedicineABIM
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Effective targeted cytotoxicity of neuroblastoma cells.
- A diphtheria toxin-interleukin 3 fusion protein is cytotoxic to primitive acute myeloid leukemia progenitors but spares normal progenitors.
- Increased sophistication of immunotoxins.
- New HER2-directed therapies for breast cancer. Commentary re: C. I. Spiridon et al., Targeting multiple Her-2 epitopes with monoclonal antibodies results in improved antigrowth activity. Clin. Cancer Res., 8: 1720-1730, 2002.
- Peptide toxins directed at the matrix dissolution systems of cancer cells.
- Diphtheria fusion protein therapy of chemoresistant malignancies.
- The majority of children and adolescents with acute myeloid leukemia have detectable anti-DT388-GMCSF IgG concentrations, but at concentrations that should not preclude in vivo activity.
- Receptor upregulation enhances cell surface receptor targeted therapies.
- The diphtheria toxin/urokinase fusion protein (DTAT) is selectively toxic to CD87 expressing leukemic cells.
- DAB389EGF fusion protein therapy of refractory glioblastoma multiforme.
- Apoptosis by leukemia cell-targeted diphtheria toxin occurs via receptor-independent activation of Fas-associated death domain protein.
- A diphtheria toxin-epidermal growth factor fusion protein is cytotoxic to human glioblastoma multiforme cells.
- Growth factor receptor expression varies among high-grade gliomas and normal brain: epidermal growth factor receptor has excellent properties for interstitial fusion protein therapy.
- Recombinant toxin DAB389EGF is cytotoxic to human pancreatic cancer cells.
- Novel protein targeted therapy of metastatic melanoma.
Dr. Arthur Edward Frankel MD's Practice location
DALLAS, TX 75390Get Direction
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