Dr. Michael Carol Snyderman M.D.
Oncologist | Medical Oncology
515 Abbott Road Suite 102 Buffalo New York, 14220About
He has practiced guideline based hematology-oncology and participated in the SUNY Buffalo training program for medical students and residents. He is focused on finding a coherent, unifying approach to cancer, inflammation and autoimmunity.
Dr. Michael Carol Snyderman M.D.'s Videos
Education and Training
Temple University
Temple Univ Sch of Med, Philadelphia Pa 1967
Temple University School of Medicine 1967
Board Certification
American Board of Internal Medicine - Internal Medicine
Medical Oncology
Hematology
Internal MedicineAmerican Board of Internal MedicineABIM- Hematology
Provider Details
Dr. Michael Carol Snyderman M.D.'s Expert Contributions
if I am anemic will i Have to have a series of blood transfusions?
Your Hematologist will look for correctable issues. It is unusual to need "a series of transfusions." READ MORE
Does fibromyalgia make you ineligible to donate stem cells?
Fibromyalgia and Chronic Fatigue Syndrome overlap quite a bit. Chronic Fatigue Syndrome may be caused by activation of viruses such as Epstein-Barr virus or Herpesvirus 6. Donating stem cells would also donate these viruses so yes, donating stem cells might be unwise. READ MORE
Cancer Anxiety
You are in the lowest risk category possible. If you still are fearful, you might consider that a manifestation of an anxiety disorder that can and should be treated. READ MORE
Can local anesthesia be used for a bone marrow biopsy?
When I did marrow biopsies I put in local anesthesia with lidocaine. I told patients it might help to take acetaminophen an hour prior. I myself had a marrow aspiration and a biopsy without much of the above. There was only brief discomfort which was bearable and I was pleased it wasn't worse than that. READ MORE
What sedation is used for bone marrow biopsy?
I have had both a bone marrow aspiration and biopsy, one immediately after the other at the Cleveland Clinic. Although it wasn't recreational, it wasn't terrible and a good local anesthetic and perhaps some acetaminophen prior should be adequate for most people. READ MORE
What condition do I have?
Most of what you have posted could be explained by your immune system being overactive and probably causing excess inflammation. In other words, you may have a disorder in the same basic category as lupus and rheumatoid arthritis rather than a blood disease. The bleeding could be related to medications such as aspirin, ibuprofen, fish oil and antidepressants. What causes the underlying overactive immune system is the subject of ongoing research so there may be treatment in the near future. READ MORE
I'm 75 With Lupus, Should I Get The Booster?
It is likely that the number of immune cells prepared to respond to an infection is less in people with autoimmune disorders such as Lupus. Some of the treatments reduce this number further. So yes, getting a booster could be lifesaving. READ MORE
Please help re: metastatic disease?
HPV has been associated with cancer of the colon and rectum, but it is not common. HPV is not looked for except in cancer of the cervix and anus (not the rectum) and cancer of the oral cavity. The original rectal cancer specimen could be tested for HPV but that would not be covered by insurance and would cost several hundred dollars. If HPV was proven to be present in the rectal cancer, unfortunately there would be a lot of skepticism that it caused the cancer. Metastasis refers to the cancer being spread, not to the virus. READ MORE
Does leukemia cause fatigue in children?
Your daughter may have Cancer-Related Fatigue (CRF), which is a common problem. There are clinics for CRF at cancer centers, and some report partial improvement. Research as to the cause of CRF is ongoing and hopefully this will lead to better treatment by the end of this year. READ MORE
What causes lymphoma to develop in adults?
The virus that causes mononucleosis, Epstein-Barr virus, is known to cause some lymphoma and closely related viruses have also been implicated. READ MORE
Stage 4 liver cancer?
If the liver cancer was caused by hepatitis C or hepatitis B, there may be some options. This is an area considered "experimental," but there is published data that shows antiviral drug treatment improves cancer outcomes. READ MORE
Can HPV cause skin cancer?
It is accepted that HPV can cause squamous cell cancer of the vulvar area. There are reports in the literature that HPV can also be found in squamous cell cancer of the skin, basal cell cancer of the skin, and even in melanoma. The HPV subtypes here may not be the same as those that classically cause squamous cell cancer of the anogenital and oropharyngeal areas. READ MORE
What can I do to control my persistent tiredness?
There is a name for what you are experiencing: Cancer-Related Fatigue (CRF). The etiology appears to be a disturbance in multiple parts of the immune system with resulting inflammation that spills over into the brain. As the cause of this immune disturbance isn't clear, there is no established treatment. Some people with CRF will benefit from s-adenosylmethionine (SAMe) 400 mg twice a day. SAMe can shut down bad genes but doesn't work in everyone and is OTC and pricey. A prescription med that is also used in lupus and Rheumatoid Arthritis, Plaquenil (hydroxychloroquine) 200 mg twice a day sometimes helps CRF. A retinal specialist has to OK this medication as there is a very small chance of retinal damage. READ MORE
Can cancer cause short-term memory loss?
Cancer can be associated with "Cancer-Related Fatigue," which includes cognitive changes. This is worsened by chemotherapy and is then called "chemo-brain." There is ongoing research as to whether these problems are caused by viruses, because we have medications to fight viral infection. Additionally, a B12 deficiency is common in cancer patients and can surprisingly be a difficult diagnosis to make. The serum B12 level is unreliable and the physician has to test the levels of homocysteine and methylmalonic acid, check the balance (Romberg sign) and examine the blood smear. READ MORE
Should I take certain vitamins or supplements after being diagnosed with pancreatic cancer? Which ones?
Vitamin D deficiency in epidemiological studies has worsened outcomes in cancer so it is reasonable to supplement it. 2000 u/day is safe, but clear this with your primary physician. The other vitamins are problematical. In tissue culture, s-adenosylmethionine (SAMe) shuts down cancer genes but although this is available as a supplement, it has never entered clinical trial so we don't know if it would work with cancer patients. READ MORE
Expert Publications
Data provided by the National Library of Medicine- Disseminated intravascular coagulation in Rocky Mountain spotted fever.
- Immune complexes in breast cancer patients as detected by C1q binding.
- Immune complexes in breast cancer patients as detected by C1q binding.
- Characterization of immune complexes from the pleural effusion of a breast cancer patient.
- Characterization of immune complexes from the pleural effusion of a breast cancer patient.
Areas of expertise and specialization
Faculty Titles & Positions
- Assistant Clinical Professor of Medicine, SUNY Buffalo, 1990-2011 -
- Attending, Mercy Hospital of Buffalo, Catholic Hospital System of WNY -
- Past Chief of Hematology and Oncology, Mercy Hospital of Buffalo, 1978-2005 -
- Medical Grand Rounds and Presentations at Meetings and Hospital Research Symposium -
Awards
- Best Teaching Attending, Mercy Hospital/SUNY Buffalo Residents, 1983, 1990, 2005
- Love Award for Outstanding Service, Mercy Hospital of Buffalo, 2012
Internships
- Temple University
Fellowships
- Roswell Park Medical Institute (Medical Oncology); Temple University (Hematology)
Professional Society Memberships
- American Society of Clinical Oncology, American Oncology Association Honorary Medical Society
Articles and Publications
- Two articles on Clonal T-Cells and Anti-retroviral Drugs, published in the American Society of Clinical Oncology Journal
What do you attribute your success to?
- He will consider himself successful only if he can stimulate further research and treatment in what he considers his life's work.
Areas of research
- Viral Oncology and the Immunology of Cancer. He is working with two scientists, Judy Mikovits and her mentor, Francis Ruscetti who co-discovered HTLV1. He is looking up antibody to murine leukemia Env and the presence of clonal T-cell expansion and monocytosis. The goal is to help improve cancers with antiretroviral drug therapy. They are actively looking for collaboration with other scientists and clinicians in academia.
Hobbies / Sports
- Music, Art
Areas of research
Viral Oncology and the Immunology of Cancer. He is working with two scientists, Judy Mikovits and her mentor, Francis Ruscetti who co-discovered HTLV1. He is looking up antibody to murine leukemia Env and the presence of clonal T-cell expansion and monocytosis. The goal is to help improve cancers with antiretroviral drug therapy. They are actively looking for collaboration with other scientists and clinicians in academia.Dr. Michael Carol Snyderman M.D.'s Practice location
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