Mrs. Karen Dezelan OTR
Occupational Therapist
8820 ANCHOR BAY CT INDIANAPOLIS IN, 46236About
Dr. Karen Dezelan practices Occupational Medicine in INDIANAPOLIS, IN. Dr. Dezelan evaluates the interaction between work and health. Occupational medicine physicians have general knowledge of worksite operations and are familiar with the toxic properties of materials used by employees and the potential hazards and stressors of work processes; in addition to being qualified to determine an employees physical and emotional fitness for work; diagnosing and treating occupational diseases; handling work related injuries; and having an understanding of rehabilitation methods, health education techniques, sanitation, and workers compensation laws.
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Susceptibilities of Mycobacterium tuberculosis and Mycobacterium avium complex to
- Antimycobacterial activities of 2,4-diamino-5-deazapteridine derivatives and effects on mycobacterial dihydrofolate reductase.
- Synthesis and antifolate evaluation of the aminopterin analogue with a bicyclo.
- Hydroxy derivates of S-2-(3-aminopropylamino)ethyl dihydrogen phosphorothioate and related compounds as antiradiation agents.
- Synthesis and antifolate evaluation of 10-ethyl-5-methyl-5,10- dideazaaminopterin
- Synthesis and antifolate evaluation of the 10-propargyl derivatives of 5-deazafolic acid, 5-deazaaminopterin, and 5-methyl-5-deazaaminopterin.
- Mobility of the spin-labeled side chains of some novel antifolate inhibitors in their complexes with dihydrofolate reductase.
- Tetrahydrohomofolate polyglutamates as inhibitors of thymidylate synthase and glycinamide ribonucleotide formyltransferase in Lactobacillus casei.
- Hydrolytic cleavage of methotrexate gamma-polyglutamates by folylpolyglutamyl hydrolase derived from various tumors and normal tissues of the mouse.
- Syntheses and antifolate activity of 5-methyl-5-deaza analogues of aminopterin, methotrexate, folic acid, and N10-methylfolic acid.
- Folylpolyglutamate synthetase inhibition and cytotoxic effects of methotrexate analogs containing 2,omega-diaminoalkanoic acids.
- Folate analog nonsubstrates and inhibitors of folylpolyglutamate synthetase as potential cancer chemotherapy drugs.
- Inhibition of glycinamide ribonucleotide formyltransferase and other folate enzymes by homofolate polyglutamates in human lymphoma and murine leukemia cell extracts.
- Structural design, biochemical properties, and evidence for improved therapeutic activity of 5-alkyl derivatives of 5-deazaaminopterin and 5-deazamethotrexate compared to methotrexate in murine tumor models.
- Synthesis and antifolate activity of 5-methyl-5,10-dideaza analogues of aminopterin and folic acid and an alternative synthesis of 5,10-dideazatetrahydrofolic acid, a potent inhibitor of glycinamide ribonucleotide formyltransferase.
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