David Zolezzi PA-C
Physician Assistant | Medical
1501 W PECAN ST STE 102 PFLUGERVILLE TX, 78660About
David Zolezzi is a physician assistant practicing in PFLUGERVILLE, TX. David specializes in preventing and treating human illness and injury by providing a broad range of care under the supervision of a physician. A physician assistant's work can include physical exams, ordering and interpreting tests, performing procedures and prescribing medication. Often times, they can assist in surgery but the scope of practice can vary according to jurisdiction or health care setting.
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Expert Publications
Data provided by the National Library of Medicine- The ligandin (non-substrate) binding site of human Pi class glutathione transferase is located in the electrophile binding site (H-site).
- Structure and function of the bacterial mechanosensitive channel of large conductance.
- Macromolecular crystallography as a tool for investigating drug, enzyme and receptor interactions.
- Structures of thermolabile mutants of human glutathione transferase P1-1.
- Valine 10 may act as a driver for product release from the active site of human glutathione transferase P1-1.
- Crystallization of two glutathione S-transferases from an unusual gene family.
- Structural biology and its applications to the health sciences.
- The crystal structures of glutathione S-transferases isozymes 1-3 and 1-4 from Anopheles dirus species B.
- Structural flexibility modulates the activity of human glutathione transferase P1-1. Influence of a poor co-substrate on dynamics and kinetics of human glutathione transferase.
- The three-dimensional structure of the human Pi class glutathione transferase P1-1 in complex with the inhibitor ethacrynic acid and its glutathione conjugate.
- Multifunctional role of Tyr 108 in the catalytic mechanism of human glutathione transferase P1-1. Crystallographic and kinetic studies on the Y108F mutant enzyme.
- The structures of human glutathione transferase P1-1 in complex with glutathione
- The glutathione conjugate of ethacrynic acid can bind to human pi class glutathione transferase P1-1 in two different modes.
- Solution structure of glutathione bound to human glutathione transferase P1-1: comparison of NMR measurements with the crystal structure.
- Evidence for an induced-fit mechanism operating in pi class glutathione transferases.
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