Dr. James Earl Franzbrooke D.O.
Family Practitioner
10465 MELODY DR NORTHGLENN CO, 80234Rating
4/5
About
Dr. James Franzbrooke is a family practitioner practicing in NORTHGLENN, CO. Dr. Franzbrooke specializes in comprehensive health care for people of all ages. In addition to diagnosing and treating illnesses, family practitioners also put focus on preventative care with routine checkups, tests and personalized coaching on how to maintain a healthy lifestyle. Dr. Franzbrooke possesses immense general knowledge on maintaining health and today, family practitioners provide more care for the underserved and rural populations than any other medical specialty.
Board Certification
Family MedicineAmerican Board of Family MedicineABFM
Provider Details
Expert Publications
Data provided by the National Library of Medicine- Activation of extracellular signal-regulated kinase is involved in mechanical strain inhibition of RANKL expression in bone stromal cells.
- The role of nitric oxide in the mechanical repression of RANKL in bone stromal cells.
- The PPARγ ligand rosiglitazone attenuates hypoxia-induced endothelin signaling in vitro and in vivo.
- The Nox4 inhibitor GKT137831 attenuates hypoxia-induced pulmonary vascular cell proliferation.
- Peroxisome proliferator-activated receptor gamma (PPARγ) regulates thrombospondin-1 and Nox4 expression in hypoxia-induced human pulmonary artery smooth muscle cell proliferation.
- Hypoxia downregulates PPARγ via an ERK1/2-NF-κB-Nox4-dependent mechanism in human pulmonary artery smooth muscle cells.
- Chronic hypoxia promotes pulmonary artery endothelial cell proliferation through H2O2-induced 5-lipoxygenase.
- Peroxisome proliferator-activated receptor gamma depletion stimulates Nox4 expression and human pulmonary artery smooth muscle cell proliferation.
- Targeting mitochondrial reactive oxygen species to modulate hypoxia-induced pulmonary hypertension.
- Smooth Muscle-Targeted Overexpression of Peroxisome Proliferator Activated Receptor-γ Disrupts Vascular Wall Structure and Function.
- Time-dependent PPARγ Modulation of HIF-1α Signaling in Hypoxic Pulmonary Artery Smooth Muscle Cells.
- Peroxisome Proliferator-Activated Receptor γ Regulates the V-Ets Avian Erythroblastosis Virus E26 Oncogene Homolog 1/microRNA-27a Axis to Reduce Endothelin-1 and Endothelial Dysfunction in the Sickle Cell Mouse Lung.
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Nearby Providers
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Dr. Debra Salter M.D.10268 W Centennial Rd Ste 204 Littleton CO 80127![]()
Dr. Gregory Dean Smith D.O.19515 E 54TH PL DENVER CO 80249![]()
Patricia Horvath NP9116 W Bowles Ave Littleton CO 80123![]()
Dr. Kristen Harvey Other1650 28TH ST UNIT 1232 BOULDER CO 80301![]()
Dr. Arlyn LaBair MD8289 E LOWRY BLVD DENVER CO 80230![]()
Dr. Michael B Keller M.D.1700 Marion Street Denver CO 80218
Nearest Hospitals
ST ANTHONY NORTH HEALTH CAMPUSl
14300 ORCHARD PARKWAY WESTMINSTER CO 80023GOOD SAMARITAN MEDICAL CENTERl
200 EXEMPLA CIRCLE LAFAYETTE CO 80026