

John F. Wagener, MD, FACC, FSCAI
Cardiologist | Interventional Cardiology
4520 W 69th St Sioux Falls SD, 57108About
Dr. John F. Wagener is a board-certified interventional cardiologist with specialized training in structural heart intervention, who diagnoses and treats patients at North Central Heart Institute at Avera Heart Hospital in Sioux Falls, SD. As a structural interventional cardiologist, Dr. Wagener specializes in the catheter-based treatment of both coronary artery and structural heart diseases. His expertise covers transcatheter aortic valve replacement (TAVR), balloon aortic valvuloplasty, transcatheter edge-edge valvular repair (MitraClip, TriClip), transcatheter mitral valve replacement, transcatheter tricuspid valve replacement, balloon mitral valvuloplasty, paravalvular leak closure, alcohol septal ablation, PFO closure, atrial septal defect closure, ventricular septal defect closure, pulmonary vein stenting, left atrial appendage occlusion (WATCHMAN), coronary artery angioplasty and stenting, coronary atherectomy, and mechanical circulatory support (Impella).
John F. Wagener, MD, FACC, FSCAI's Videos
Education and Training
University of North Dakota School of Medicine and Health Sciences MD 2012
Board Certification
American Board of Internal Medicine; Internal Medicine
American Board of Internal Medicine; Cardiovascular Disease Medicine
American Board of Internal Medicine; Interventional Cardiology
American Board of Nuclear Medicine; Nuclear Medicine
Provider Details
Areas of expertise and specialization
Faculty Titles & Positions
- Associate Clinical Professor of Medicine University of South Dakota 2020 - Present
- Medical Director Avera Heart Hospital 2022 - Present
- Medical Director of Cardiovascular Disease Avera McKennan University Hospital 2022 - Present
- Cardiologist Avera Heart Hospital and North Central Heart - Present
- Cardiologist Avera Heart Hospital and North Central Heart - Present
Professional Memberships
- American College of Cardiology
- American Heart Association
- Society for Cardiovascular Angiography and Interventions
Fellowships
- Cleveland Clinic interventional cardiology 2020
- Cleveland Clinic cardiovascular medicine 2018
Fellowships
- Cleveland Clinic Foundation - Cardiology and Interventional/Structural Cardiology fellowship
Professional Society Memberships
- ACC, SCAI, AHA
Professional Affiliations
- Fellow of the American College of Cardiology (ACC)Fellow of the Society of Cardiac Angiography and Interventions (SCAI)
John F. Wagener, MD, FACC, FSCAI's Practice location
North Central Heart Institute
4520 W 69th St -Sioux Falls, SD 57108Get Direction
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Dedicated to Heart Health and Patient-Centered Excellence in Sioux Falls, South Dakota
Dr. John F. Wagener is a highly skilled interventional cardiologist passionate about providing exceptional cardiovascular care at Avera Heart Hospital and North Central Heart, a division of Avera Heart Hospital in Sioux Falls, South Dakota. He is committed to patient comfort and expertise and is dedicated to serving individuals of all ages facing heart-related health challenges.
"Serving patients is my favorite part of my job. When something is wrong with your cardiovascular system, it can be scary, so being a source of comfort and expertise is rewarding," Dr. Wagener expressed. His compassionate approach ensures patients receive the highest medical care and the emotional support they need during difficult times.
Dr. Wagener specializes in diagnosing and treating various heart diseases and related conditions. His comprehensive services include lifestyle modification consultations, angiograms, cardiac catheterizations, and advanced interventions tailored to address various heart and vascular illnesses. His expertise extends to numerous cutting-edge procedures, including transcatheter aortic valve replacement, balloon aortic valvuloplasty, MitraClip procedures, and more.
Dr. Wagener, a graduate of the University of North Dakota School of Medicine and Health Sciences, completed his prestigious Duke University Medical Center residency. He further honed his skills through fellowships in cardiovascular medicine and interventional/structural cardiology at the renowned Cleveland Clinic Foundation. This extensive training equips him with the knowledge and skills to provide the highest standard of cardiovascular care.
With a commitment to professional excellence, Dr. Wagener is board-certified in internal medicine, cardiovascular disease, and interventional cardiology by the American Board of Internal Medicine. He also holds board certification in nuclear cardiology from the American Board of Nuclear Medicine. He is a proud Fellow of the American College of Cardiology (FACC) and the Society for Cardiovascular Angiography and Interventions (FSCAI).
With a focus on providing comprehensive, compassionate care, Dr. John F. Wagener is poised to impact the Sioux Falls community's cardiovascular health significantly. Patients seeking expert care for heart conditions can trust Dr. Wagener to guide them to better health.
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Nearest Hospitals
SANFORD USD MEDICAL CENTERl
1305 W 18TH ST POST OFFICE BOX 5039 SIOUX FALLS SD 57117AVERA HEART HOSPITAL OF SOUTH DAKOTAl
4500 W 69TH ST SIOUX FALLS SD 57108