Daniel Soffer, MD

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Get to know Interventional Cardiologist Dr. Daniel Soffer, who serves patients in Jacksonville, Florida.

Dr. Soffer is an associate professor of medicine and director of endovascular cardiology at UF Health Jacksonville Florida and board certified in Cardiovascular Disease, Interventional Cardiology and Endovascular medicine. He performs coronary, peripheral and structural heart interventions including TAVR, Mitraclip (TMVR) and Watchman procedures as well as PFO, ASD and VSD closures. In 2019 he performed the first two trans-caval TAVRs in the entire North Florida region at UF Health in Jacksonville.

Dr Soffer completed his medical school with high honors at the Ben Gurion University in Beer Sheva, Israel followed by one year of rotating internship at the Sheba Medical Center in Tel Hashomer, the largest hospital in Israel. He then moved to NYC after meeting his wife Osi in Israel and completed 3 years of internal medical residency and received excellent cardiovascular fellowship training at Lenox Hill hospital from 1994 to 2000. He then moved his family with three small children to Michigan and completed a two-year interventional cardiology, peripheral and structural heart fellowship at William Beaumont hospital in Royal Oak, under the world-renowned interventional cardiologists William O’Neill and Cindy Grines. After completing his interventional fellowship, he joined a private group in Greenville, NC which was affiliated with East Carolina University where he developed a carotid stent program at Pitt County Memorial Hospital, working with interventional radiologists and vascular surgeons.

After spending 2 years in NC Dan was recruited by his mentor, Dr Gary Roubin to join him and his team at Lenox Hill Hospital in NYC as the associate director of the interventional cardiology fellowship program. From 2004 to 2011 he was a member of the coronary, peripheral and structural heart interventional teams at Lenox Hill Hospital, working with world renowned interventional cardiologists. He then decided to move to Mount Sinai Hospital in NYC and from 2011 to 2015 he worked at as the Co-director of the Carotid endovascular Services and as the Director of the vascular medicine laboratory at the Mount Sinai Heart and Vascular center in midtown Manhattan.

After 11 years in NYC Dan decided to move to Florida and over the last 8 years at UF Health he developed a robust endovascular program, training interventional fellows in diagnostic and peripheral interventions, performing over 350 endovascular procedures annually, many of them in patients with critical limb ischemia. Over the last few years he developed and expanded the non-invasive vascular lab, performing over 800 vascular studies annually including ABI’s, carotid duplex, arterial ultrasound and venous mapping. He also developed the structural heart interventional program training his fellows with over 150 structural heart interventions annually. In addition to endovascular and structural heart interventions He performs over 150 coronary procedures annually including high risk and complex coronary interventions using the Impella LV assist device.

Over the last 23 years he performed thousands of coronary and peripheral interventions and hundreds of structural heart and carotid stent procedures as well as limb salvage procedures using cutting edge technology. He trained dozens of national and international interventional fellows at Lenox Hill Hospital, Mount Sinai Hospital in NYC and for the last 8 years at the University of Florida in Jacksonville. He is a fellow of the American College of Cardiology and the Society for Cardiac Angiography and Interventions.

In addition to his clinical work Dr Soffer has been a principle and co-investigator in numerous clinical trials assessing new pharmacologic therapies and regimens during coronary interventions and new techniques and devices in the coronary, carotid, peripheral as well as structural heart interventional arenas. Recently one of his philanthropic patients donated a significant amount of money in his honor to start an advanced fellowship (PGY-8) in Endovascular and structural heart interventions beginning in the summer of 2024.

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