Amosy Ephreim M\'Koma, M.D., Ph.D., M.S., Surgeon
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Amosy Ephreim M\'Koma, M.D., Ph.D., M.S.

Surgeon

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About

Dr. Amosy M'Koma is a colon and rectal surgeon and physician-scientist in Nashville, TN.  Dr. M'Koma is specialized in diseases of the colon, rectum and anus. As a colon and rectal surgeon, Dr. M'Koma often treated colonic conditions like inflammatory bowel disease (IBD), rectal cancer, colon cancer, hemorrhoids, anal fissures, fistulae, and diverticulitis. Patients with colon and rectal conditions are referred to specialists by their gastroenterologists for evaluation and possible surgical intervention. Dr. M'Koma's research constitutes the development of a point-of-care, rapid, and accurate diagnosis of IBD that potentially qualifies as NIH-FDA-defined “Diagnostic” “Prognostic” and Monitoring” biomarker(s) [PMID: 22729569].

Education and Training

Kharkov Medical Institute MD 1984

Karolinska Nobel Institute Residency, Surgery 1990

Karolinska Nobel Institute Licentiate, Surgery 1999

Karolinska Nobel Institute PhD, Surgery 2001

Mayo Clinic, Rochester, MN Clinical Research Fellow 2004

Vanderbilt Un Medical Center Postdoctoral Clinical Fellow 2007

Board Certification

Surgery (Physician Specialties)

Provider Details

Male English, Russian

Areas of expertise and specialization

Diseases of the colon, rectum and anus, especially inflammatory bowel disease (IBD).

Faculty Titles & Positions

  • Professor Meharry Medical College and Vanderbilt University Medical Center 2022 - Present

Awards

  • Methods for Diagnosing and Treating Inflammatory Bowel Disease 2022 US Patent Bureau 
  • Targeted DEFA5 Antibody Assay Methods for Diagnosing and Treating. Inflammatory | US Patent Bureau. Appl. | 2018 2018 US Patent Bureau. Appl. 

Professional Memberships

  • The American Society of Colon and Rectal Surgeons  
  • The American Gastroenterological Association  
  • Vanderbilt Digestive Disease Research Center  
  • Vanderbilt Colorectal Research Center  
  • Vanderbilt-Ingram Cancer Center  
  • International Society of University Colon and Rectal Surgeons  
  • NIH/NCI: Early Detection Research Network [EDRN], and Data Management Center [DMCC].  

Charities and Philanthropic Endeavors

  • The American African Health Team, LLC - https://americanafricanhealthteam.com/

Treatments

  • Diseases of the colon, rectum and anus, especially surgical treatment of Ulcerative colitis (UC) and Familial adenomatous polyposis (FAPC).

Fellowships

  • Clinical Research Fellow, Colon and Rectal Surgery, Mayo Clinic, Rochester, Minnesota, United States, 2004.

Professional Society Memberships

  • The American Society of Colon and Rectal Surgeons (ASCRS); The American Gastroenterological Association (AGA); International Society of University Colon and Rectal Surgeons (ISUCRS); Vanderbilt Digestive Disease Research Center [VDDRC]; Vanderbilt Colorectal Research Center (VCRC); Vanderbilt-Ingram Cancer Center (VICC); Swedish Medical Association [SMA]; Surgical Research Society [SRS].

Professional Affiliations

  • School of Medicine, Meharry Medical College and Vanderbilt University Medical Center

Articles and Publications

  • https://www.ncbi.nlm.nih.gov/sites/myncbi/amosy.m'koma.1/bibliography/43900962/public/?sort=date&dire

What do you attribute your success to?

  • My mother and IBD patients

Areas of research

  • Pathophysiology of inflammatory bowel disease (IBD) and to develop a diagnostic tool in IBD appealing to hospitals, clinics, diagnostic laboratories and others

Awards

  • *American Society of Colon and Rectal Surgeons [ASCRS], The New England Society of Colon and Rectal Surgeons, Regional Society Receiving Award for Best Clinical Podium Presentation, 2016. *Research Foundation, American Society of Colon, and Rectal Surgeons, Grant LPG-086, 2009. *American Society of Colon and Rectal Surgeons [ASCRS], The New Jersey Society of Colon and Rectal Surgeons, Regional Society Receiving First Award for Best Scientific Presentation, 2009.

Teaching and speaking

  • Medical students (MD program), Clinical skills, Postdoctoral fellows, Graduate students (PhD program). Invited guest speaker to national and international scientific meetings,

Favorite Place to Vacation

  • North America, Europe and Africa.

Hobbies / Sports

  • Soccer, Boxing and Tennis

Favorite professional publications

  • https://www.ncbi.nlm.nih.gov/sites/myncbi/amosy.m'koma.1/bibliography/43900962/public/?sort=date&dire

Areas of research

Inflammatory bowel disease (IBD). The research aims to develop a gold standard diagnostic tool, an unmet gap  to assist IBD healthcare personnel and patients worldwide, especially in low-middle-income nations with a non-invasive test that shows promise for changing the landscape of IBD diagnostics and could be used in doctor’s office labs, clinics, or hospitals. IBD is increasingly evolving worldwide and has become a global emerging emergent disease. IBD, which includes Crohn's disease (CD) and ulcerative colitis (UC), has been considered a problem in industrial-urbanized societies and attributed largely to a Westernized lifestyle and other associated environmental factors. Its incidence and prevalence in low-middle-income countries are steadily rising and have been attributed to the rapid modernization and Westernization of the population. There is a need to reconcile the most appropriate treatment for these patient populations from disease presentation and cost perspectives.

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Media Releases

Unveiling the Pathophysiology of IBD and Advancements in Diagnostics and Surgical Management

Nashville, Tennessee - Dr. Amosy Ephreim M'Koma, an oncologist and distinguished Professor of Surgery, Surgical Sciences, Pathology and Cancer Biology at Meharry Medical College, and adjunct Professor of Surgery specialized in Colon and Rectal Surgery at Vanderbilt University Medical Center has been at the forefront of innovative research in the field of IBD. With a career spanning over three decades, Dr. M'Koma’s unwavering commitment to advancing diagnostic methodologies and surgical treatments for colonic conditions such as ulcerative colitis and familial adenomatous polyposis has garnered international recognition.

Dr. M'Koma’s journey in the medical field began with his Medical Degree from Kharkov Medical Institute in Ukraine, followed by postgraduate studies and a surgical residency program at Karolinska University Hospital, Huddinge, Stockholm, in Sweden. Having been Board Certified in General Surgery by The Swedish Board of Health and Welfare, Dr. M'Koma furthered his academic pursuits with a Licentiate of Medical Science Degree and a Ph.D. in Surgery from the prestigious Karolinska Nobel Institute.

Upon relocating to the United States, Dr. M'Koma honed his expertise at the Mayo Clinic in Rochester, Minnesota, where he collaborated with leading experts in Colon and Rectal Surgery. This invaluable experience laid the foundation for his groundbreaking research on predominantly colonic IBD, emphasizing the importance of molecular diagnostic methodologies and surgical interventions in the management.

Dr. M'Koma’s current research focuses on the restorative physiology of intestinal continuity post-surgical procedures for IBD, particularly pouch surgery, the restorative proctocolectomy. Leveraging cutting-edge technologies such as MALDI-mass spectrometry, proteomics, and recombinant single-chain antibodies, his work aims to identify peptides that offer precise diagnostic tools for IBD as “Gold Standard”. There is a pressing unmet need to develop noninvasive or minimally invasive novel biomarkers with improved performance to address the diagnostic challenges facing IBD patients to provide optimal patient care and develop new drug candidates. No single diagnostic gold standard is available for the distinction of IBD colitis and this uncertainty has not changed over the past 60 years and that IBD incidence is now acknowledged as a global emergent disease affecting a much younger population, a serious concern.

In addition to his academic contributions, Dr. M'Koma is an esteemed member of various professional organizations including the American Society of Colon and Rectal Surgeons, the American Gastroenterological Association, the Vanderbilt Digestive Disease Research Center, the Vanderbilt Colorectal Research Center, the Vanderbilt-Ingram Cancer Center, the International Society of University Colon and Rectal Surgeons. His dedication to collaborative research is underscored by his involvement with the NIH/NCI Early Detection Research Network and Data Management Center.

Reflecting on his success, Dr. M’Koma attributes his achievements to unwavering focus, relentless dedication, and a collaborative spirit. His commitment to improving patient outcomes and advancing the field of gastrointestinal surgery is evident in his extensive bibliography and long-standing affiliations with esteemed institutions.

For more information about Dr. Amosy Ephreim M'Koma’s research and publications, please visit: https://www.ncbi.nlm.nih.gov/sites/myncbi/amosy.m'koma.1/bibliography/43900962/public/?sort=date&dire 

Beyond his professional endeavors, Dr. M'Koma finds joy in sports, particularly soccer and tennis, and enjoys exploring diverse cultures through travel, with a particular fondness for North America, Europe, and Africa.

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