Diane Smith Pilch P.T.
Physical Therapist
729 Cedar Hill Rd Ambler PA, 19002About
Diane Pilch is a physical therapist practicing in Ambler, PA. Diane Pilch specializes in physical treatment to help a patient reduce pain, restore mobility, rehabilitate an injury, or increase movement and overall function. As a physical therapist, Diane Pilch can treat multiple conditions with exercises, ultrasound, electrical stimulation, joint mobilization, heat, ice, massage, laser or light therapy and more. Diane Pilch will create a treatment plan based on the patients specific injury or condition, and might target a specific body part or body system based on the individual.
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Expert Publications
Data provided by the National Library of Medicine- The thermodynamics of polyamide-DNA recognition: hairpin polyamide binding in the minor groove of duplex DNA.
- DNA sequence context modulates the impact of a cisplatin 1,2-d(GpG) intrastrand cross-link on the conformational and thermodynamic properties of duplex DNA.
- Aminoglycoside binding in the major groove of duplex RNA: the thermodynamic and electrostatic forces that govern recognition.
- Heterocyclic bibenzimidazole derivatives as topoisomerase I inhibitors.
- Human topoisomerase I poisoning by protoberberines: potential roles for both drug-DNA and drug-enzyme interactions.
- 2"-Substituted 5-phenylterbenzimidazoles as topoisomerase I poisons.
- Site-specific topoisomerase I-mediated DNA cleavage induced by nogalamycin: a potential role of ligand-induced DNA bending at a distal site.
- A spectrophotometric study of the pH-dependent and DNA binding properties of topotecan.
- A structural model for the ternary cleavable complex formed between human topoisomerase I, DNA, and camptothecin.
- Calorimetry of nucleic acids.
- Ligand-induced formation of nucleic acid triple helices.
- The thermodynamics of DNA structures that contain lesions or guanine tetrads.
- Nucleic acid hybridization: triplex stability and energetics.
- Binding of a hairpin polyamide in the minor groove of DNA: sequence-specific enthalpic discrimination.
- Influence of cisplatin intrastrand crosslinking on the conformation, thermal stability, and energetics of a 20-mer DNA duplex.
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