Bruce Edward Clurman
Oncologist | Medical Oncology
University Of Washington Medical Ctr 1959 Ne Pacific St Seattle WA, 98195About
Dr. Bruce Clurman is an oncologist practicing in Seattle, WA. Dr. Clurman specializes in the care and treatment of patients with cancer. As an oncologist, Dr. Clurman manages and oversees the treatment of a cancer patient after he or she has been diagnosed with the disease. Oncologists will care for their patients throughout the course of the disease. Types of oncologists include medical oncologists, surgical oncologists, radiation oncologists, gynecologic oncologists, pediatric oncologists and hematologist oncologists.
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Expert Publications
Data provided by the National Library of Medicine- Proteasomal turnover of p21Cip1 does not require p21Cip1 ubiquitination.
- Nup50, a nucleoplasmically oriented nucleoporin with a role in nuclear protein export.
- Characterization and targeted disruption of murine Nup50, a p27(Kip1)-interacting component of the nuclear pore complex.
- Identification of oncogenes collaborating with p27Kip1 loss by insertional mutagenesis and high-throughput insertion site analysis.
- Npap60/Nup50 is a tri-stable switch that stimulates importin-alpha:beta-mediated nuclear protein import.
- p53 and p21 form an inducible barrier that protects cells against cyclin E-cdk2 deregulation.
- Cycling without CDK2?
- Multisite phosphorylation by Cdk2 and GSK3 controls cyclin E degradation.
- The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation.
- Recognition of phosphodegron motifs in human cyclin E by the SCF(Fbw7) ubiquitin ligase.
- Notch activation induces endothelial cell cycle arrest and participates in contact inhibition: role of p21Cip1 repression.
- A nucleolar isoform of the Fbw7 ubiquitin ligase regulates c-Myc and cell size.
- N-acetylation and ubiquitin-independent proteasomal degradation of p21(Cip1).
- The SV40 large T antigen contains a decoy phosphodegron that mediates its interactions with Fbw7/hCdc4.
- Cyclin E in normal and neoplastic cell cycles.
Bruce Edward Clurman's Practice location
Practice At University Of Washington Medical Ctr 1959 Ne Pacific St
University Of Washington Medical Ctr 1959 Ne Pacific St -Seattle, WA 98195Get Direction
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Nearby Providers
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Dr. Stephen H. Culp M.D.1959 Ne Pacific St Seattle WA 98195![]()
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Dr. Maciej Mrugala MD PHD MPH1959 Ne Pacific St Seattle WA 98195![]()
Dr. Cheryl A Carlson MD1959 Ne Pacific St Seattle WA 98195![]()
Dr. Nandita Khera MD1959 Ne Pacific St Seattle WA 98195
Nearest Hospitals
SWEDISH MEDICAL CENTERl
747 BROADWAY SEATTLE WA 98122GROUP HEALTH CENTRAL HOSPITALl
201 - 16TH AVENUE EAST SEATTLE WA 98112SEATTLE CHILDREN'S HOSPITALl
4800 SAND POINT WAY NE, PO BOX C-5371 SEATTLE WA 98105