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Desloratadine(antihistamine) and pseudoephedrine(decongestant) is a combination drug used for the treatment of nasal congestion, sneezing, and runny nose. This combination drug works by preventing the effects of histamine such as itching, sneezing, runny nose, and watery eyes. 

Also, the pseudoephedrine causes narrowing of blood vessels leading to clearance of nasal congestion. This drug combination requires a prescription. 

Serious or possibly life-threatening side effects have been associated with the use of this drug to children under 4 years of age.

 

Before taking this drug, the risks and benefits for your body should be discussed with your healthcare provider. Inform your healthcare provider for any allergic reactions to these drugs or any other drugs, foods, dyes, preservatives, or animals. 

Carefully read the label of non-prescription drugs for any possible allergic reaction or contraindications. This drug is not recommended for use in children under 12 years of age. Studies have not determined whether this drug combination works exactly the same way in the elderly as compared to younger adults.  

Elderly patients have increased sensitivity to the effects of this drug. Adverse effects have been reported in animalsbut there are no adequate studies in pregnant women animals. Studies are still inadequate regarding infant risk when taking this drug combination during breastfeeding. 

Discuss with your healthcare professional the potential risks and benefits before taking this drug while breastfeeding. 

Drugs should not be taken together to prevent any interactions but in necessary cases inquire your healthcare provider regarding the adjustments in dosage or any other necessary precautions to prevent any unwanted side effects. 

Inform your healthcare professional if you are taking any other drugs such as Dihydroergotamine, Furazolidone, Iproniazid, Isocarboxazid, Linezolid, Methylene Blue, Moclobemide, Nialamide, Phenelzine, Procarbazine, Rasagiline, Safinamide, Selegiline, Tranylcypromine, Guanethidine, Iobenguane I 123, Methyldopa, or Midodrine. Intake of specific food or using alcohol or tobacco with magnesium is associated with an increased risk of certain side effects. 

Your healthcare professional can give you special instructions about the use of food, alcohol, or tobacco. To prevent any other conditions from getting worse, inform your healthcare provider for any other medical problems such as diabetes mellitus, enlarged prostate or urinary tract blockage or difficult urination, glaucoma, heart or blood vessel diseases, hypertension, kidney or liver diseases or overactive thyroid.

This drug must be taken exactly as prescribed by your doctor to reduce the chances of any side effects. When taking this drug combination, refrain from taking over-the-counter antihistamines and decongestants. Do not crush, break, or chew the extended-release form of this drug combination. The dose of this drug will be variable for different patients. 

The directions on the label or the prescription by your healthcare professional should be followed. The dosage of this drug you take depends on the medical problem for which you are using this drug.  

Adults and teenagers with nasal congestion or rhinorrhea are given extended-release tablets once or two times depending on the dose, taken with or without a meal while use and dose in children 4 years of age and older must be determined by your healthcare professional. Use in children and infants up to 4 years of age is not recommended.

A missed dose should be taken as soon as possible. However, skip the missed dose and go back to your regular dosing schedule if it is almost time for your next dose. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. 

Keep from freezing. Keep out of the reach of children. Dispose any outdated or expired drugs and ask your healthcare professional for the proper disposal of the drugs

This drug may cause dryness of the mouth, nose, and throat. Use sugarless candy or gum, melt bits of ice in your mouth, or use a saliva substitute for relief. 

Consult with your dentist if your mouth continues to feel dry for more than 2 weeks as this may increase the chance of dental disease, including tooth decay, gum disease, and fungal infections.

Side effects may vary for each individual and prompt medical attention should be given if they occur. Inform you healthcare provider immediately if you experience symptoms such as abdominal or stomach pain, chills, clay-colored stools, cough, dark urine, difficult or labored breathing, difficulty swallowing, dizziness, elevated liver enzymes, fast heartbeat fast, pounding, or irregular heartbeat or pulse, fever, general tiredness and weakness, headache, hives, irregular heartbeat, itching, light-colored stools, loss of appetite, nausea, puffiness or swelling of the eyelids or around the eyes, face, lips or tongue, rash, redness of skin, shortness of breath, skin rash, swelling, tightness in chest, unpleasant breath odor, unusual tiredness or weakness, upper right abdominal pain, vomiting of blood, vomiting, welts, wheezing ,yellow eyes or skin, increased heart rate, sleepiness or unusual drowsiness. Some side effects may occur that usually do not need medical attention. 

As your body adjusts to the medicine, the side effects will slowly disappear. Ask your healthcare professional about ways to prevent or reduce some of these side effects. If any of the following side effects persists, or are inconvenient, or if you notice any other effects, or if you have any questions about them, consult with your health care professional. 

If any of the following side effects persists, or are inconvenient, or if you notice any other effects, or if you have any questions about them, consult with your health care professional. Report any side effects to the FDA hotline at 1-800-FDA-1088.