Integrilin

1 What is Integrilin?

Brand: Integrilin

Generic: Eptifibatide

Integrilin is an anti-platelet drug used for the prevention of blood clots from forming in the arteries of the heart after certain types of chest pain and heart attacks. This drug can also be used for cardiovascular procedures such as coronary angioplasty. This drug is to be given only by or under the direct supervision of a healthcare professional.

2 What to Know Before Using

If you are about to start Integrilin, speak with your doctor about what you need to know.

Before taking this drug, the risks and benefits for your body should be discussed with your healthcare provider. Inform your healthcare provider for any allergic reactions to these drugs or any other drugs, foods, dyes, preservatives, or animals. Carefully read the label of non-prescription drugs for any possible allergic reaction or contraindications.

Studies in children regarding the the correlation of age to the effects of eptifibatide injection have not been performed whiel safety and efficacy have not been established. Studies in the elderly have not reported any geriatric-specific problems that would limit the utility of eptifibatide injection.

Caution is required for elderly patients taking this drug since they are more likely to have bleeding problems. No data is suggesting harm to the fetus of animal while studies in pregnant women or animals are still inadequate.

This drug has not been shown to cause any risk to the fetus. Infant risk is still undetermined when taking this drug during breastfeeding. Discuss with your healthcare professional about the risks and benefits of this drug before breastfeeding. Drugs should not be taken together to prevent any interactions but in necessary cases inquire your healthcare provider regarding the adjustments in dosage or any other necessary precautions to prevent any unwanted side effects.

Inform your healthcare professional if you are taking any other drugs such as:

  • Abciximab
  • Tirofiban
  • Aceclofenac
  • Acemetacin
  • Alipogene
  • Tiparvovec
  • Alteplase
  • Amtolmetin
  • Guacil
  • Anagrelide
  • Apixaban
  • Ardeparin
  • Argatroban
  • Aspirin
  • Bivalirudin
  • Bromfenac
  • Bufexamac
  • Celecoxib
  • Certoparin
  • Choline Salicylate
  • Cilostazol
  • Citalopram
  • Clonixin
  • Clopidogrel
  • Dabigatran
  • Etexilate
  • Dalteparin
  • Danaparoid
  • Desirudin
  • Desvenlafaxine
  • Dexibuprofen
  • Dexketoprofen
  • Diclofenac
  • Diflunisal
  • Dipyridamole
  • Dipyrone
  • Droxicam
  • Duloxetine
  • Edoxaban
  • Enoxaparin
  • Escitalopram
  • Etodolac
  • Etofenamate
  • Etoricoxib
  • Felbinac
  • Fenoprofen
  • Fepradinol
  • Feprazone
  • Floctafenine
  • Flufenamic Acid
  • Fluoxetine
  • Flurbiprofen
  • Fluvoxamine
  • Fondaparinux
  • Heparin
  • Ibuprofen
  • Ibuprofen Lysine
  • Indomethacin
  • Ketoprofen
  • Ketorolac
  • Lepirudin
  • Levomilnacipran
  • Lornoxicam
  • Loxoprofen
  • Lumiracoxib
  • Meclofenamate
  • Mefenamic Acid
  • Meloxicam
  • Milnacipran
  • Morniflumate
  • Nabumetone
  • Nadroparin
  • Naproxen
  • Nefazodone
  • Nepafenac
  • Niflumic Acid
  • Nimesulide
  • Oxaprozin
  • Oxyphenbutazone
  • Parecoxib
  • Parnaparin
  • Paroxetine
  • Phenindione
  • Phenprocoumon
  • Phenylbutazone
  • Piketoprofen
  • Piroxicam
  • Prasugrel
  • Proglumetacin
  • Propionic Acid
  • Propyphenazone
  • Proquazone
  • Protein C
  • Reviparin
  • Rivaroxaban
  • Rofecoxib
  • Salicylic Acid
  • Salsalate
  • Sodium Salicylate
  • Sulfinpyrazone
  • Sulindac
  • Tenoxicam
  • Tiaprofenic Acid
  • Ticagrelor
  • Ticlopidine
  • Tinzaparin
  • Tolfenamic Acid
  • Tolmetin
  • Treprostinil
  • Valdecoxib
  • Venlafaxine
  • Vilazodone
  • Vortioxetine
  • or Warfarin

Intake of specific food or using alcohol or tobacco with this drug is associated with an increased risk of certain side effects. Your healthcare professional can give you special instructions about the use of food, alcohol, or tobacco.

Inform your healthcare provider for any other medical problems such as:

3 Proper Usage

Proper usage of Integrilin requires strict adherence to your doctor’s orders.

A trained healthcare professional will be the only to give you this drug. This drug is administered intravenously through a needle placed into one of your veins. This drug can be used with as aspirin or heparin. You will receive a continuous infusion of this drug over a period of up to 4 days. You will be monitored closely to check if the drug is working and if it is not causing unwanted side effects.

4 Precautions to Take

In using Integrilin, you must be careful and take some precautions as advised by your doctor.

Regular visits should be made to your healthcare provider to track your progress and to monitor the effectiveness of the drug. Unwanted effects can be screened using blood tests. Avoid injuries until the effects of this drug have worn off as this drug may cause you to bleed and bruise more easily. The effects can last for up to 2 or 3 days.

Seek advice from your healthcare professional immediately if you notice any unusual bleeding or bruising, black, tarry stools, blood in the urine or stools, or pinpoint red spots on your skin.

Avoid picking or blowing you nose. You may be advised to use a soft toothbrush or to shave with an electric razor for a few days after being prescribed with this drug to reduce the risk of bleeding. Watch for any bleeding from open areas such as sites of needle punctures for drawing blood, giving shots, or putting in a catheter for a heart catheterization or angioplasty.

Inform your healthcare professional if you notice blood in your urine or stool. Consult with your healthcare professional before taking any other prescription or non-prescription drugs, and herbal or vitamin supplements.

5 Potential Side Effects

As with many medications, there are several potential side effects associated with Integrilin.

Side effects may vary for each individual and prompt medical attention should be given if they occur. Seek advice from your healthcare professional immediately if you experience any unusual symptoms such as:

  • Abdominal
  • Stomach pain
  • Swelling
  • Back pain or backaches
  • Bleeding from the bladder
  • Bleeding gums
  • Blood in the urine
  • Bloody or black, tarry stools
  • Blurred vision
  • Confusion
  • Constipation
  • Coughing up blood
  • Difficulty with breathing or swallowing
  • Dizziness
  • Faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • Headache
  • Increased menstrual flow or vaginal bleeding
  • Nausea and vomiting
  • Nosebleeds
  • Paralysis
  • Prolonged bleeding from cuts
  • Red or black, tarry stools
  • Red or dark brown urine
  • Severe stomach pain
  • Shortness of breath
  • Sweating
  • Unusual tiredness or weakness
  • Vomiting of blood or material that looks like coffee grounds
  • Weakness
  • Pinpoint red spots on the skin
  • Cough
  • Difficulty with swallowing
  • Fast heartbeat
  • Hives
  • Itching
  • Puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • Skin rash
  • Tightness in the chest
  • Wheezing
  • Difficulty with speaking
  • Double vision
  • Inability to move the arms, legs, or facial muscles
  • Inability to speak, or slow speech

Ask your healthcare professional about ways to prevent or reduce some of these side effects. If any of the following side effects persists, or are inconvenient, or if you notice any other effects, or if you have any questions about them, consult with your health care professional. Report any side effects to the FDA hotline at 1-800-FDA-1088.

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